Folate supplement options are essential for those looking to enhance their nutritional intake and support overall health. In 2025, the market offers a variety of high-quality folate supplements that cater to different needs, ensuring that individuals can find the right product for their lifestyle. From natural sources to synthetic forms, these supplements provide vital support for cellular function and can be particularly beneficial for pregnant women and those planning to conceive. With a focus on bioavailability and effectiveness, the best folate supplements of the year stand out for their purity and potency.
SALE
−$2.20
Nature Made Folic Acid 400 mcg (665 mcg DFE), Dietary Supplement for Nervous System Function, 250 Tablets, 250 Day Supply
- Nervous system support supplement: contains one 250 count bottle of Nature Made Folic Acid 400 mcg (665 mcg DFE) Tablets for a 250-day supply
- This Folic Acid supplement contains an important B vitamin for women of childbearing age and pregnant women
- These Folic acid supplements support nervous system function, and play a critical role in the proper development of the baby's nervous system
- Adults take one of these Folic Acid tablets daily with water and a meal
- These gluten free Folic Acid vitamins for women have no color added, no artificial flavors and no preservatives
$4.79
Life Extension BioActive Folate & Vitamin B12, Promotes Heart, Brain & GI Tract Health, Non-GMO, Gluten-Free, Vegetarian, 90 Capsules
- Folate in the body – 5-MTHF is the metabolically active form of folic acid and supports healthy DNA function, helps maintain normal homocysteine levels, and supports GI and immune function.
- Benefits of vitamin B12 – B12 is a vital member of the vitamin B family. The biologically active form of B12, methylcobalamin, supports cognitive health, nerve cell growth and metabolism.
- The importance of vitamin B – These two biologically active forms of B9 and B12 ensure that you are covering your bases and getting the many benefits of these forms of vitamin B.
- Ingredients matter – We use the finest raw ingredients with the quality and purity you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one.
- Live your healthiest life – We believe the answers to a healthier life are in reach, and that scientific research is the key to getting there. That’s why so many of our formulas feature specific ingredients and amounts based on scientific studies.
$9.00
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−$6.34
Doctor's Best Fully Active Folate with Quatrefolic400 mcg, Healthy Mood, Memory, Circulation, Well-Being, 90 VC
- Quatrefolic contains the natural form of folic acid. It is the most bioavailable form of folate that provides greater stability and water solubility.
- Quatrefolic is the metabolically active folate, making it more efficient than folic acid for maximized benefits.
- Folate is an essential vitamin to support DNA
- Helps support cardiovascular, mental, and emotional well-being
$8.65
SALE
−$8.53
NOW Foods Supplements, Methyl Folate 1,000 mcg, Metabolically Active Folate*, Co-Enzyme B Vitamin, 90 Tablets
- CO-ENZYME B VITAMIN/1,000 mg TABLETS: Methylfolate is the biologically active, naturally occurring form of folate that is used for fundamental body functions like normal cell division and the synthesis of neurotransmitters and DNA.
- METABOLICALLY ACTIVE FOLATE/SUPERIOR BIOAVAILABLITY: Quatrefolic is a patented form of methylfolate that has demonstrated bioavailability superior to that of folate from dietary sources.
- CERTIFICATIONS/CLASSIFICATIONS: Non-GMO, Vegan/Vegetarian
- GMP Quality Assured: NPA A-rated GMP certification means that every aspect of the NOW manufacturing process has been examined, including our laboratory/testing methods (for stability, potency, and product formulation).
- Packaged in the USA by a family owned and operated company since 1968
$13.46
THORNE 5-MTHF - Methylfolate (Active B9 Folate) Supplement - Supports Cardiovascular Health, Fetal Development, Nerve Health, Methylation, and Homocysteine Levels* - 60 Capsules - 5-MTHF 1mg
- Healthy Methylation: A breakthrough in active folate supplementation for healthy methylation*
- Positivity: Supports a healthy outlook*
- Nerves & Circulation: Supports healthy blood vessel and nerve function*
- Cardiovascular Support: Providing the nutritional cofactors for optimal homocysteine metabolism supports cardiovascular health*
- Trusted: Thorne is chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of 11 U.S. Olympic Teams
$24.00
4 TOP CARE Folate Dietary Supplement, 1,333 mcg DFE, 400 Count
- Dosage form : Capsule
- Flavor : Unflavored
- Item form : Tablet
- Item dimensions : 2.5 inches
- Primary supplement type : Prenatal Vitamins, Letter Vitamins
$12.95
Life Extension Optimized Folate – L-methylfolate – Heart & Brain Support, Healthy Homocysteine Levels – Non-GMO, Gluten-Free, Vegetarian – 1700 mcg DFE, 100 Vegetarian Tablets
- Get a brain boost – Stay proactive about your brain health and support optimal cognitive function with this folate supplement. This 1700 mcg vitamin B formula helps maintain healthy cognition—especially as you age.
- Pump up the heart health – This 5-MTHF supplement is a cardiovascular health superstar! Folate helps maintain already-normal homocysteine levels, an important cardiovascular health marker. Folate is a great way to keep heart health in check.
- Metabolically active form – 5-MTHF, the metabolically active form of folate, is good for your heart and brain health. But not everyone can convert the dietary form of folate (known as folic acid) into 5-MTHF. This supplement provides folate’s 5-MTHF form.
- Ingredients matter – We use only the finest raw ingredients with the purity and potency you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one.
- Live your healthiest life – We believe the answers to a healthier life are within reach, and that scientific research is the key to getting us there. That’s why so many of our formulas feature specific ingredients and amounts based on scientific studies.
$11.25
Pure Encapsulations Folate 1000 - Metafolin L-5-MTHF - Heart Health Supplement* - Folate Supplement - Non-GMO & Gluten Free - 90 Capsules
- Heart Health Ally: Pure Encapsulations Folate is a universally metabolized form of folate, supporting cardiovascular, cellular, and neurological well-being*
- Folate Supplement: Each folate capsule contains 1,667 mcg DFE (1,000 mcg L-5-MTHF) Metafolin, making it an optimal MTHF supplement*
- Benefits All Users: This heart health supplement provides all of the benefits of folic acid regardless of MTHFR genetic variations
- Suggested Use: As a dietary supplement, take 1 Pure Encapsulations Folate capsule daily, with a meal; formula is non-GMO, vegan, and gluten free
- Pure Difference: What we leave out matters, too; Pure Encapsulations products are FREE FROM common allergens, artificial or unnecessary ingredients, and GMOs
$33.00
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−$9.82
Solgar Folate 1000 mcg, 120 Tablets - 1000 mcg Bio-active Metafolin - Heart Health - Vegan, Gluten Free, Dairy Free, Kosher - 120 Servings
- BODY READY – In order for the body to use Folic Acid, it must undergo a series of biochemical steps. The active folate in Solgar Folate is Metafolin (L-methyfolate) which is bioidentical to the bioactive form, which means no conversion by the body.
- BENEFITS – The active folate in this formulation helps in promoting heart health as well as providing support for a healthy nervous system as well as the formulation of healthy red blood cells.
- SUITABLE FOR VEGANS – All capsules are non-GMO and certified gluten free. They are also free of wheat, dairy, soy, yeast, sugar, sodium, artificial flavors, sweeteners, preservatives and colors.
- The Gold Standard; For over 70 years, Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials
$23.17
Methylfolate 1,000mcg, 120 Capsules (Third Party Tested Methyl Folate Supplement) Methylated Folate is a More Active Form of Folate Than Folic Acid (Non-GMO, Vegan Safe) by Double Wood
- MORE ACTIVE FORM OF FOLATE: Recent research suggests that Methylfolate is a more active form of folate when compared to Folic Acid. Folic Acid is the synthetic form of Folate
- METABOLICALLY ACTIVE 5-MTHF (OPTIMIZED FOLATE): Methylfolate is the biological and active form of Folate. It is more immediately absorbed into the bloodstream and requires little processing by the body
- METHYLFOLATE vs METHYL B12: Methylfolate (known as B9) and Methyl B12 are the active forms of Folate and B12 and are readily used by the body compared to non-methylated forms of the same vitamins
- ROOTED IN QUALITY: Manufactured and Tested in the USA from Globally Sourced Ingredients. Double Wood's Methylfolate is manufactured and tested for microbes and heavy metals right here in the USA from Globally Sourced Ingredients. Plus,it is vegetarian, Non-GMO and gluten-free
- WE BOTTLE WELLNESS: At Double Wood we provide pure, potent supplements that deliver exceptional value, all backed by careful sourcing and rigorous third-party testing
$7.95
Last update on 2025-05-03 / Affiliate links / Images from Amazon Product Advertising API