OTC probiotic options have gained immense popularity for their potential to support gut health and overall well-being. In 2025, the market is brimming with top-rated over-the-counter probiotics that cater to various health needs, from digestive support to immune enhancement. These products are formulated with diverse strains of beneficial bacteria, ensuring that consumers can find the right match for their specific requirements. Whether you're looking for a daily supplement or something to address occasional digestive discomfort, the best OTC probiotics of 2025 offer effective solutions for everyone.
SALE
−$0.70
Nature's Bounty Acidophilus Probiotic, Daily Probiotic Supplement, Supports Digestive Health, 1 Pack, 120 Tablets
- PROVIDES FRIENDLY BACTERIA: Designed to provide friendly bacteria to both your digestive & immune systems, Nature’s Bounty Acidophilus Probiotic contains 100 million active Lactobacillus Acidophilus cultures that are guaranteed through expiration (1)
- CONTAINS LACTOBACILLUS ACIDOPHILUS LA_14: This probiotic strain is naturally found within the intestinal tract
- ONE-PER-DAY PROBIOTIC SUPPLEMENT: Simply take one tablet daily, preferably with a meal, to provide your gut with friendly bacteria (1)
- GLUTEN, DAIRY, AND WHEAT FREE: Nature’s Bounty Acidophilus Probiotic is gluten free, dairy free, wheat free, and is suitable for vegetarians
- UNSURPASSED QUALITY AND VALUE: Using the latest breakthroughs in nutritional science and the finest ingredients, Nature’s Bounty provides supplements of unsurpassed quality and value
$7.76
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−$5.50
Rephresh Pro-B Probiotic Supplement for Women, 30 Oral Capsules
- Gynecologist Recommended brand
- Helps maintain feminine health
- Just one capsule per day
- Developed by doctors
$22.99
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−$1.80
Culturelle Daily Probiotic Gummies for Women & Men, Berry Flavor, 52 Count, Naturally-Sourced Daily Probiotic + Prebiotic for Digestive Health, Non-GMO & Vegan
- PROBIOTIC FOR DIGESTIVE HEALTH: Culturelle probiotics are naturally sourced and formulated to keep your digestive system in balance; restocking good bacteria in your gastrointestinal microbiome
- PROVEN EFFECTIVE STRAINS: Culturelle Daily Probiotic Gummies for Men & Women are formulated with 2 billion CFUs of good bacteria, these naturally flavored gummies work to restore good bacteria and support digestive & immune health
- PROBIOTIC/PREBIOTIC POWER: Your gut microbiome is essential to overall health; The bacteria that live in your gut are linked to digestive health, cognition, mood, & your immune system; Culturelle Daily Probiotic Gummies support a healthy microbiome
- SAFE & EASY TO TAKE: Enjoy two (2) delicious berry-flavored gummies daily with or without food
- INGREDIENTS YOU CAN FEEL GREAT ABOUT: Gummies are made specifically with the strains that survive in a gummy & maintain their potency within the bottle; Colors are from fruits & vegetables; no sugary coating; store in a cool, dry place away from sunlight
$13.99
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−$13.29
Nature's Bounty Probiotic 10 Daily Probiotic Supplement for Digestive, Immune, and Upper Respiratory Support, Ultra Strength, 30 Capsules 1 Pack
- GUT HEALTH + IMMUNE SUPPORT: Our Probiotic 10 nutritional supplement support digestive and immune system; promoting overall well-being with clinically studied strains for digestive balance and immune health support (1)
- MULTI-STRAIN PROBIOTIC: Each capsule includes a probiotic complex with 10 unique strains; help supplement your GI microbiome's diversity for optimal digestion and wellness (1)
- 20 BILLION CFU PER CAPSULE: Get 20 billion live probiotics per capsule that support your digestive system (1)
- EASY ONE-PER-DAY FORMULA: Take one probiotic capsule daily with a meal to support digestive, immune, and upper respiratory health, providing optimal wellness through gut health supplements (1)
- TRUSTED QUALITY & RESEARCH: With over 20 years of research, our Nature's Bounty Probiotic 10 is backed by 50 years of trusted quality; providing a reliable supplement (1)
$12.80
Florastor Probiotics for Digestive and Immune Health, 100 Capsules, Probiotics for Women & Men, Helps Flush Out Bad Bacteria, Boosts The Good with Our Unique Strain Saccharomyces Boulardii
- Dual action support: Florastor probiotic helps strengthen digestive support; probiotics for women and men help flush bad bacteria and allow good bacteria to flourish; helps provide immune support and improve digestion by breaking down carbs and sugars*
- Unique strain: These probiotic supplements contain 250mg of the exclusive probiotic strain Saccharomyces boulardii CNCM I-745 for overall gut health; this effective probiotic supplement strain has over 65 years of use and research*
- Daily probiotics for digestive health: To build digestive health and support immunity, take 2 capsules 1-2 times daily*
- Shelf stable: 3-year shelf life; no refrigeration required; exposure to heat or sunlight may lead to melting or damage to the product
- The probiotics of choice: The number 1 selling probiotic in its class worldwide; Florastor formulas are made with ingredients that are vegetarian, gluten-free, titanium dioxide-free and appropriate for lactose intolerance
$62.06
NATURE TARGET Probiotics for Women, 100 Billion CFUs Probiotic with Digestive Enzymes & Prebiotics, Vaginal Probiotics with Cranberry for Urinary Tract Health, pH Balance, 90 Veggie Capsules
- Gut Health Support: Combine the power of 100 Billion CFUs probiotics from 31 strains, prebiotics, enzymes, women's health blend, and multivitamins to create an all-in-one gut health solution that’s easy and effective. High-potency probiotics offer 90 capsules in a shelf-stable bottle and 50 Billion CFUs in each capsule, you can adjust the dosage if you need, so the servings up to 45 days and even more. Nurture your gut health with our cost-effective probiotic solution.
- Complete Digestive Health: Digestive enzymes help break down food to turn into energy, boost nutrient absorption, and relieve gas & bloating. Probiotics help replenish the gut flora aid in digestion balance, reduce constipation & diarrhea. Prebiotic fibers produce short-chain fatty acids and promote probiotic growth. Probiotics and prebiotics with enzymes work together make your digestion in top shape.
- Maintain Vaginal & Urinary Tract Health: D-mannose sticks impurities and detoxifies, Cranberry stops bad flora adherence, Hibiscus and Dandelion increase flow to flush away, probiotics for pH balance. Fivefold action works fast to relieve burning, itchiness, and odors. A superior formulation restores proper balance and cleanliness in women's intimate area. No sugar, calories, or preservatives that are safe to take daily for boosting wellness.
- Skin & Immune Support: Mix cranberry, hibiscus and honeysuckle, along with multivitamins that are rich in fiber and antioxidants into a probiotic capsule to support skin care and immune support for menopause. They work together to fight against free radical-induced aging, detox cleanses, and improve your body’s immune response.
- Our Advantage: Advanced enteric-coated capsules boast an acid-resistant coating that won't irritate the stomach lining. Delayed-release properties ensure optimal strain delivery to the intestine and vagina, maximizing effectiveness. Formulated with all-natural, dairy-free, and Non-GMO ingredients. No refrigeration required. We stand behind our probiotics' potency until the expiration date and offer a return policy if it does not meet your expectations.
$17.49
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−$7.81
Physician's CHOICE Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics - Immune, Digestive & Gut Health - Supports Occasional Constipation, Diarrhea, Gas & Bloating - for Women & Men - 60ct
- Max Strength General Probiotic 2 Month Supply (60ct) : Our probiotic is designed to support digestive health & gut health. A great choice for those looking to support a diverse healthy microbiome w/ 60B CFU - Probiotics for Women & Men alike. Same great product you love, with a new look. Packaging May Vary!
- Support Your Gut: Our probiotic contains 10 diverse high-quality probiotic strains and organic prebiotics - synergistically working together to support your gut health. Expertly crafted to support occasional constipation, diarrhea, gas & bloating!
- Survives the Gut: From start to finish - this probiotic is designed to survive the gut & maximize the colonization of our strains. We use a shelf-stable bottle, acid-resistant capsules, and 60 Billion Colony forming units (CFU) to achieve this!
- Backed By Science - Our probiotics are crafted based on scientific research. We have partnered with a network of expert physicians to help review our products & research. We strive to educate & help you with informed decisions regarding your health.
- Safety Assured Standard of Quality: Our 60B probiotic is 3rd-party tested for purity and potency. Each bottle is manufactured with love & care in the USA with strict quality control - using imported and domestic ingredients.
$33.27
Probiotics 150 Billion CFU - 40 Strain Probiotics for Women, Probiotics for Men and Adults - Shelf Stable Probiotic with Organic Prebiotic - Acidophilus Probiotic - 150 Capsules - Made in USA
- ✅ 150 BILLION CFU, 40 STRAIN – Here comes the ultimate probiotics for adults with natural prebiotics & essential digestive enzymes. MOM NUTRIX probiotic contains 150 billion CFU per serving with 40 strain probiotic for women and men to maintain overall wellbeing.
- ✅ IMMUNITY & DIGESTION SUPPORT - This 150 billion CFU vegan probiotic supplement contains 40 strain of all essential probiotics like Lactobacillus acidophilus, paracasei, brevis and bulgaricus as well as Bifidobacterium lactis and longum to support digestive health & and immune system.
- ✅ PURE, POTENT & SHELF STABLE – MOM NUTRIX probiotic capsules formulated with 100% pure natural Ingredients and independently tested in 3rd Party Labs in USA. The shelf stable formula ensures the perfect potency till the expiry date without refrigeration.
- ✅ DELAYED & TARGETED RELEASE - Our unique TARGETED RELEASE formula helps the Probiotics pills survive stomach acids and reach your intestinal track. All natural probiotics provides support for the establishment and maintenance of favorable intestinal flora.
- ✅ BUY WITH CONFIDENCE - With confidence and pride we stand behind our product. Our own laboratory is GMP and ISO certified, which will give you idea about our strict quality control. Still if we fall short of your expectations, feel free to contact us. You will get 100% moneyback without any question asked. Hit the BUY NOW with confidence!
$29.95
Align Probiotic, Bloating Relief + Food Digestion, Probiotics for Women and Men, Probiotic Helps Soothe Occasional Bloating*, With Vitamin B12 to Help Break Down Food into Cellular Energy*,60 Gummies
- #1 DOCTOR RECOMMENDED PROBIOTIC BRAND. Align Probiotic is the #1 probiotic brand recommended by doctors for over 10 years running and is recommended nearly 2X more than any other probiotic brand.
- HELPS SOOTHE OCCASIONAL BLOATING*. Align Bloating Relief + Food Digestion Gummies adds good bacteria to your gut to help soothe occasional bloating and promote a healthy digestive system.*
- DIGESTION AID*. Align Bloating Relief + Food Digestion Gummies contain Vitamin B12 to help promote the breakdown of fats and proteins in food into cellular energy.*
- GREAT TASTING STRAWBERRY FLAVOR AND CONVENIENT. Align Bloating Relief + Food Digestion Gummies are easy to chew, don’t require water to take, and packed with delicious strawberry flavor.
- MONEY BACK GUARANTEE. We proudly stand behind the performance of Align. However, if you are not satisfied with your experience, we offer a Money Back Guarantee. Try Align Bloating Relief + Food Digestion Gummies risk-free today!***
$24.98
Florastor Advanced Gas and Bloat Probiotic, Digestive Enzymes and Botanicals, Plus Probiotics for Digestive Health, 30 Capsules
- Our proprietary blend: Florastor's Dual Action Probiotic with digestive enzymes and botanicals to help protect against occasional gas, bloating, and diarrhea; provides bloating relief for women and men.*
- Unique strain: This supplement contains the clinically studied probiotic strain Saccharomyces boulardii CNCM I-745 for overall gut health; this effective strain has over 70 years of safe use and research*
- Targeted ingredients: Probiotics with digestive enzyme blend of Amylase, Protease, Cellulase and Lipase, as well as botanicals ginger, fennel seed and peppermint leaf to provide bloating and gas relief for adults*
- Daily enzymes for digestion: To support digestive health and immunity, take 2 capsules 1-2 times daily with meals *
- The probiotics of choice: The number 1 selling probiotic strain in its class worldwide; Florastor formulas are made with ingredients that are vegetarian, gluten-free, titanium dioxide-free and appropriate for lactose intolerance
$28.97
Last update on 2025-05-03 / Affiliate links / Images from Amazon Product Advertising API