OTC eye drops for dry eyes are essential for providing relief and comfort to those suffering from this common condition. In 2025, the market offers a variety of effective options that cater to different needs, including preservative-free formulas, gel drops for longer-lasting moisture, and those enriched with soothing ingredients. These eye drops can help alleviate symptoms such as irritation, redness, and discomfort, making daily activities more enjoyable. Whether you prefer a simple drop or a more advanced formulation, there’s an ideal choice for everyone.
SALE
−$1.05
Refresh Tears, Lubricant Eye Drops, 2 Bottles .5 fl oz (15 ml)
- IMMEDIATE DRY EYE RELIEF: Quickly alleviates dryness, irritation, and discomfort by replenishing moisture to the eyes.
- MIMICS NATURAL TEARS: Formulated to closely resemble natural tears, providing soothing and effective hydration.
- CONTACT LENS COMPATIBLE: Safe for use with contact lenses, making it convenient for individuals with corrective eyewear.
- GENTLE DAILY FORMULA: Non-irritating and suitable for frequent use to maintain eye comfort throughout the day.
- PROTECTIVE MOISTURE BARRIER: Helps shield eyes from further dryness and irritation caused by environmental factors.
$14.70
Systane Ultra Lubricant Eye Drops, Artificial Tears for Dry Eye, Twin Pack, 10-mL Each
- #1 Dr Recommended Brand of Artificial Tears*, packaging may vary
- Extended Protection
- Fast Long-Lasting Dry Eye Symptom Relief.Store at room temperature
- Reduces both the signs and symptoms of dry eye
- Quickly soothe irritated eyes wherever you are
$16.93
LUMIFY Redness Reliever Eye Drops, For Whiter & Brighter Looking Eyes, 0.25 Fl Oz (7.5 mL)
- Eye Drops for Red Eyes: LUMIFY significantly reduces redness to help reveal your eyes' natural radiance. From the eye care experts at Bausch and Lomb, LUMIFY works in 1 minute and lasts up to 8 hours
- LUMIFY is different: The only OTC drop to contain brimonidine. It selectively targets redness, alleviating some potential side effects associated with other redness relief drops, when used as directed
- LUMIFY contains no bleach or dyes. It’s Doctor recommended redness reliever (data on file)
- Eye Care Experts at Bausch and Lomb: For over 150 years, we have focused on innovation and quality in eye care products, from contact lenses and solutions to eye drops, ointments, eye vitamins, and more
- Amazing Looking Eyes: We understand how important eyes are. And despite all the eye creams, mascara, eyeliners and eyeshadows, if your eyes are red, you won’t look your best
$21.74
Clear Eyes Triple Relief Eye Drops, Relieves Redness & Calms Irritation, 0.5 Fl Oz
- Clear Eyes Triple Action Lubricant Eye Drops relieve redness, irritation, & lubricates mild dry eyes
- Contains 2 types of lubricants to soothe and moisturize dry eyes
- Relieves redness due to minor irritations
- Helps protect against further irritations
- From the #1 selling brand of eye drops
$3.92
SALE
−$1.01
Systane Ultra Lubricant Eye Drops,0.14 Fl Oz (Pack of 1)
- Dr Recommended Brand of Artificial Tears
- Extended Protection
- Fast Long-Lasting Dry Eye Symptom Relief
- Reduces both the signs and symptoms of dry eye
- Quickly soothe irritated eyes wherever you are
$5.48
SALE
−$1.06
LUMIFY Redness Reliever Eye Drops, For Whiter & Brighter Looking Eyes, 0.08 Fl Oz (2.5 mL)
- EYE DROPS FOR RED EYES: LUMIFY redness reliever eye drops significantly reduce redness to help reveal your eyes' natural radiance. From the eye care experts at Bausch + Lomb, LUMIFY works in 1 minute & lasts up to 8 hours.
- LUMIFY IS DIFFERENT: LUMIFY eye drops are one of a kind. LUMIFY is the only over-the-counter drop that contains the active ingredient brimonidine, which works to selectively target redness, alleviating some of the potential side effects associated with other redness relievers, when used as directed.
- FDA APPROVED: LUMIFY contains no bleach or dyes and is FDA approved. LUMIFY eye drops significantly reduce redness to help eyes appear whiter, brighter, and more radiant. It's the #1 Eye Doctor recommended redness reliever (based on IQVIA survey)
- WHAT CAUSES EYE REDNESS? Eye redness, unrelated to infection or injury, is a common condition that can be caused by eye fatigue, dryness or dust, overexposure to the sun, allergies, swimming in chlorinated pools, or contact lenses.
- AMAZING LOOKING EYES: We understand how important eyes are. And despite all the eye creams, mascara, eye-liners and shadows, if your eyes are red, you won't look your best.
$11.93
SALE
−$1.73
Blink Eye Drops for Dry Eyes, Triple Care Lubricant Eye Drops, Instantly Soothing, Moisturizing & Extra Long-Lasting Hydrating Eye Care for Moderate to Severe Dry Eye Symptom Relief, 0.34 fl oz
- Relief with every Blink: Experience extended dry eye symptom relief with Blink Triple Care Lubricating Eye Drops. This 3-in-1 formula instantly soothes, gives extra long-lasting hydration, and seals in moisture.
- Dry Eye Lubricant: Discover what makes Blink Triple Care Lubricating Eye Drops different from other eye drops. Our drops for dry eyes have a dual-action moisture seal to lock in moisture for instant, long-lasting relief.
- Long-Lasting Hydration: Blink Triple Care Lubricating Eye Drops are formulated with hyaluronate - also found in your eyes - to boost hydration. Hydrate like your tears for extra long-lasting comfort
- Reduce Everyday Discomfort: These dops for dry eyes deliver extended relief for moderate to severe dry eye symptoms
- Trusted Brand: Blink has a range of products to meet your eye and contact lens care needs, from drops for dry eyes to lock in moisture, to preservative-free formulas; and contact lens drops to keep your contacts clean and hydrated.
$13.26
SALE
−$7.89
OCuSOFT Retaine MGD Ophthalmic Emulsion - Complete Dry Eye Relief - Soothes Red & Irritated Eyes - 30 Count Preservative-Free Single-Use Containers - 0.01 Fl Oz
- Retained mgd is a revolutionary preservative-free ophthalmic emulsion that moisturizes, lubricates and protects moderate to severe dry eyes
- Provides long-lasting relief utilizing nova orb,
- Proprietary cationic oil emulsion technology that effectively delivers ingredients through electrostatic attraction between positively charged droplets and the negatively charged ocular surface
- Retained MGD is a revolutionary preservative-free ophthalmic emulsion that moisturizes, lubricates and protects moderate to severe dry eyes.
- The hypo tonicity of the emulsion adds moisture by lowering the salt concentration of tears while the lipid component lubricates and protects the surface of the eye.
$22.11
SALE
−$4.00
Refresh Optive MEGA-3 Lubricant Eye Drops Preservative-Free Artificial Tears, 0.01 fl oz (0.4 mL), 30 Single-Use Containers
- FAST-ACTING: Rapid relief to comfort dry, irritated eyes
- LASTING RELIEF: Soothes and prevents further irritation
- TRIPLE-ACTION FORMULA: Lubricates, hydrates, and protects tears from evaporating
- PRESERVATIVE-FREE: Enhanced with antioxidants and plant-based Flaxseed Oil (inactive ingredients) which contains omega-3s
- ADVANCED HYDRATION: Innovated with patented HydroCell technology that enables rehydration
$17.99
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API