Decongestant for stuffy nose can provide much-needed relief when you're feeling under the weather. In 2025, the market offers a variety of effective options that can help clear nasal passages and ease breathing. From over-the-counter medications to natural remedies, these decongestants work by reducing swelling in the nasal tissues and promoting drainage. Whether you prefer a pill, spray, or herbal solution, there’s a decongestant tailored to your needs. Explore the top choices to find the best fit for your symptoms and regain your comfort.
SALE
−$2.52
Vicks Sinex SEVERE Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Stuffy Nose due to Cold or Allergy, & Nasal Congestion, Sinus Pressure Relief, 265 Sprays x 2
- Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses
- Breathe better all day or all night long with Vicks Sinex Severe. For instant, 12-hour, nasal congestion and sinus pressure relief
- This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell, Not intended for daily use
- Unlike nasal decongestant tablets, Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes
- Vicks Sinex Severe Nasal Spray is HSA and FSA eligible, Check with your provider for more details
$14.97
Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays
- Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses
- Breathe better all day or all night long with Vicks Sinex Severe. For instant, 12-hour, nasal congestion and sinus pressure relief
- This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell, Not intended for daily use
- Unlike nasal decongestant tablets, Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes
- Vicks Sinex Severe Nasal Spray is HSA and FSA eligible, Check with your provider for more details
$10.46
Vicks Sinex Severe Nasal Spray, Moisturizing Ultra Fine Mist with Aloe, Decongestant Medicine, Relief from Stuffy Nose Due to Cold or Allergy, Nasal Congestion & Sinus Pressure Relief, 265 Sprays x 2
- INSTANT SINUS RELIEF: Vicks Sinex Severe Nasal Spray clears your stuffy nose in seconds and works 6x faster vs. nasal decongestant tablets.
- LAST 12 HOURS: Breathe freely with powerful sinus and congestion relief day or night
- WORKS AT THE SOURCE: Targets nasal congestion at the source to help you breathe easier
- POWERFUL VICKS VAPORS: Vicks vapors provide soothing and comforting relief of your congestion
- MOISTURIZING: Contains hints of aloe
$17.49
Hyland's Kids Stuffy Nose and Sinus Tablets, Cold Medicine for Children Ages 2 and up, Headache Relief and Nasal Decongestant, Quick Dissolving Tablets, 50 Count
- Temporarily relieves symptoms of stuffy nose and sinus in children including: nasal congestion, sinus pressure, and headache
- Hyland's Kids medicines are made with natural active ingredients, and created especially for kids ages 2 to 12
- EASY TO TAKE: Quick-dissolving tablets that melt in your mouth almost instantly
- KEEPING FAMILIES HEALTHY: Hyland’s is a leading consumer health brand with more than a century of history making high quality products to help people live healthier and happier lives.
- Made in the USA
$10.67
SALE
−$1.42
Afrin Children's Extra Moisturizing Nasal Mist, Non-Drowsy, Fast-Acting Decongestant for up to 12 Hour Stuffy Nose Relief, Children Ages 2 to 6, .5 fl oz (Pack of 2)
- Ridiculously Fast Relief: Unblock your child's nose in seconds with Children's Afrin Extra Moisturizing Nasal Mist, a fast-acting, non-drowsy nasal spray providing up to 12-hour nasal congestion relief and moisturizing for dry noses in a convenient twin pack
- Effective for Nasal Congestion due to Colds and Allergies: Formulated for young children, this kids' nasal decongestant provides quick and effective relief from nasal congestion due to common colds, hay fever, and upper respiratory allergies
- Specially Formulated for Young Kids: Designed for children ages 2 to under 6 years, this nasal spray is gentle yet effective, ensuring safe and comfortable children's relief that unblocks stuffy noses fast
- Extra Moisturizing Formula: This nasal spray for children helps moisturize and soothe dry nasal passages, offering an effective nasal moisturizer and relief from stuffy noses
- Doctor & Pharmacist Recommended: Trust the #1 doctor and pharmacist recommended nasal spray brand (Pharmacy Times Survey) to deliver safe and effective nasal congestion relief and moisturization of dry noses for children ages 2 to under 6 years
$18.74
TUKOL Max Action Nasal Spray, Oxymetazoline Nasal Decongestant Spray for Adults, Fast Stuffy Nose & Sinus Congestion Relief, 12-Hour Nose Spray Decongestant, 0.5 fl oz
- [ POWERFUL NASAL SPRAY DECONGESTANT ]: Fast-acting oxymetazoline nasal spray for adults; provides 12-hour nasal congestion relief and stuffy nose relief due to common cold, hay fever and upper respiratory allergies
- [ FAST-ACTING NASAL CONGESTION RELIEF ]: Oxymetazoline nasal spray decongestant starts working in 10 minutes for quick stuffy nose relief for adults
- [ MOISTURIZING NASAL SPRAY FOR COMFORT ]: Oxymetazoline formula helps soothe nasal passages while delivering fast relief
- [ ACTIVE INGREDIENTS ]: Formulated with oxymetazoline hydrochloride for powerful decongestion, providing fast relief for sinus congestion and post nasal drip. Ideal for adults needing nasal care
- [ EASY DOSAGE ]: Adults and children over 12, use 2-3 sprays in each nostril every 10-12 hours. Do not exceed 2 doses in 24 hours. This nasal spray provides relief for sinus and cold symptoms
$6.49
Mucinex Children's Liquid - Stuffy Nose & Cold Mixed Berry 4 oz. (Packaging May Vary)
- MULTI-SYMPTOM RELIEF: Mucinex Children’s Stuffy Nose & Chest Congestion thins and loosens mucus, relieves chest congestion and stuffy nose
- #1 PEDIATRICIAN RECOMMENDED: Mucinex Children’s is the #1 Pediatrician Recommended Brand among Non-Homeopathic Children’s Cough / Cold OTC products
- EXPECTORANT: Contains Guaifenesin that thins and loosens mucus; relieves chest congestion
- NASAL DECONGESTANT: Contains Phenylephrine HCl that provides relief for nasal congestion, sinus congestion and pressure
- FLAVOR: Available in Very Berry Flavor
$9.97
Frida Baby NoseFrida Saline Mist Nasal Inhaler, Nasal Decongestant Spray for Congestion Relief & Allergy Relief for Babies + Kids, Nasal Saline Spray, Soothes Stuffy Nose & Sore Throat, Includes Mask
- TARGETED RELIEF: The NoseFrida Saline Mist Inhaler provides targeted relief for babies experiencing congestion and sore throat. Its inhalable saline micro-mist moisturizes the upper airways, soothing scratchy throats and addressing respiratory discomfort.
- MORE VALUE: Enjoy the convenience of 1.5 hours of continuous fine-mist, lasting 50% longer than comparable products, ensuring longer-lasting relief for your baby's symptoms.
- NO FUSS: The design of the saline mist inhaler allows for hassle-free application. Use it with or without the mask to ensure proper administration. This user-friendly feature makes it easier for babies to breathe in relief without resistance.
- SAFE + GENTLE: Rest assured knowing that the formula used in the saline mist inhaler is extra-gentle, containing only salt and water, making it safe for daily use with infants and children, without the worry of harsh chemicals or additives.
- COMPREHENSIVE RELIEF: Expand your options to address your baby's respiratory discomfort. Frida's congestion portfolio now includes the NoseFrida Saline Mist Inhaler, which targets the upper respiratory tract to soothe the throat and alleviate congestion.
$19.97
Nostrilla Nasal Decongestant Spray, Stuffy Nose Relief, 0.5 oz (3 Pack)
- Nostrilla Nasal Decongestant Spray provides fast relief for stuffy noses up to 12 Hours
- Shrinks swollen membranes and helps clear nasal passages up to 12 Hours
- Each pump from the spray delivers a measured dose of medication each time
- Effective relief of nasal congestion due to: common colds, hay fever, and allergies
$17.77
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API