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10 Best decongestant for cold (2025) - Joe's Italian Restaurant & Pizza

10 Best decongestant for cold (2025)

Decongestant for cold can provide much-needed relief during the uncomfortable days of a cold. These medications work by narrowing the blood vessels in the nasal passages, reducing swelling and congestion. In 2025, several options stand out for their effectiveness and user satisfaction. From oral tablets to nasal sprays, the best decongestants can help clear your sinuses and make breathing easier. Whether you prefer a fast-acting solution or a longer-lasting option, there’s a decongestant that can meet your needs.

SALE −$3.03

Tylenol Sinus Severe Daytime Cold & Flu Relief Medicine Caplets, Non-Drowsy Pain Reliever, Fever Reducer Expectorant & Decongestant, Acetaminophen, Guaifenesin & Phenylephrine HCl, 24 ct

  • 24-count of Tylenol Sinus Severe Daytime Medicine Caplets for non-drowsy relief of symptoms due to the common cold, flu, hay fever or other respiratory allergies such as mucus and sinus congestion
  • Pain reliever, fever reducer, decongestant and expectorant medicine temporarily relieves minor aches and pains as well as symptoms of chest congestion, nasal congestion, sinus headache and pressure
  • Each caplet contains 325 milligrams of acetaminophen to reduce fever and pain; 5 milligrams of nasal decongestant phenylephrine HCl to help clear nasal passages; and 200 milligrams of the expectorant guaifenesin to help make coughs more productive
  • The non-drowsy formula of this sinus decongestant medicine provides effective daytime symptom relief by promoting sinus drainage, decongesting sinus openings and passages, and thinning bronchial secretions to help make coughs more productive
  • From the #1 doctor recommended pain relief brand, these severe sinus relief caplets are suitable for adults and children ages 12 years and older for powerful daytime cold symptom relief

$7.64

Coricidin HBP Decongestant-Free Cough and Cold Medicine - Specially Designed Relief for High Blood Pressure, Cough, Runny Nose, Sneezing and Cold Symptoms (16 Count)

  • The no.1 brand that gives powerful cold symptom relief without raising your blood pressure
  • Provides fast, powerful cold relief for people with high blood pressure
  • Cold and cough medicine for adults that relieves cough, runny nose, and sneezing
  • Decongestant free, cough cold medicine
  • Cold medicine comes in tablet form

$8.99

Coricidin HBP Maximum Strength Cold & Flu Day & Night Sugar-Free Liquid Twinpack, Decongestant-Free Cold Medicine for Adults with High Blood Pressure -12 Fl Oz (Pack of 2)

  • Suitable for people with diabetes* *sugar free and alcohol free
  • HBP ADULT COLD MEDICINE: Decongestant-free Coricidin cold & flu medicine relieves symptoms without elevating blood pressure
  • BODY ACHES AND PAIN RELIEF: Acetaminophen reduces fever and relieves pain, including sore throat, headaches and body aches
  • COUGH RELIEF: A cough suppressant and expectorant temporarily relieves coughs and loosens congestion
  • MAXIMUM STRENGTH RELIEF: Coricidin HBP cold, cough & flu maximum strength medicine provides fast relief of symptoms for up to 4 hours
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$19.99

Coricidin HBP, Decongestant-Free Cold Symptom Relief for People with High Blood Pressure, Maximum Strength, Flu & Chest Congestion Liquid Gels, 24 Count

  • Coricidin is the #1 brand that gives powerful cold symptom relief that's specially designed for people with high blood pressure. *Based on unit sales.
  • Powerful cold & flu brand with maximum strength formula for people with high blood pressure*
  • Flu, chest congestion and cold medicine for adults that relieves sore throat, chest congestion, fever, body aches & pains, and headache
  • Cold flu, and chest congestion medicine comes in a concentrated liquid gel form
  • Coricidin HBP is a decongestant free cold, chest congestion and flu medicine

$10.46
SALE −$3.48

Coricidin HBP, Decongestant-Free Cold Symptom Relief for People with High Blood Pressure, Maximum Strength Cold & Flu Day + Night Liquid Gels, 24 Count

  • The #1 doctor recommended brand that gives fast powerful cold symptom relief that's specially designed for people with high blood pressure.
  • Powerful cold medicine with maximum strength formula for people with high blood pressure
  • Coricidin provides daytime cold and flu relief of sore throat, chest congestion, fever, body aches & pains, and headache.
  • Provides nighttime cold and flu relief of sore throat, cough, fever, runny nose, sneezing, body aches & pains, and headachee relief of sore throat, cough, fever, runny nose, sneezing, body aches & pains, and headache
  • Cold medicine comes in a concentrated liquid gel form
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$7.01
SALE −$6.00

Tylenol Cold + Flu Severe Medicine Caplets for Cold & Flu Symptom Relief, Fever Reducer, Pain Reliever, Cough Suppressant, Nasal Decongestant & Expectorant with Acetaminophen, 2 pks of 24 ct ea, 48 ct

  • Twin 2 Pack of 24-count of Tylenol Cold + Flu Severe Pain Reliever & Fever Reducer Medicine Caplets provide effective relief of multiple symptoms due to the flu and common cold
  • This severe cold & flu medicine helps relieve fever, headache, minor aches and pains, sore throat, nasal congestion, and cough. It also helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.
  • Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches & pains, as well as 10 mg of the cough suppressant dextromethorphan HBr to help quiet coughs
  • Each caplet also contains 5 mg of the nasal decongestant phenylephrine HCl to help relieve congestion and 200 mg of the expectorant guaifenesin to help loosen phlegm (mucus) and make coughs more productive
  • From the #1 doctor-recommended pain relief brand, this cold & flu medicine is suitable for use by adults and children 12 years and older for powerful multi-symptom relief

$15.34
SALE −$2.52

Vicks Sinex SEVERE Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Stuffy Nose due to Cold or Allergy, & Nasal Congestion, Sinus Pressure Relief, 265 Sprays x 2

  • Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses
  • Breathe better all day or all night long with Vicks Sinex Severe. For instant, 12-hour, nasal congestion and sinus pressure relief
  • This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell, Not intended for daily use
  • Unlike nasal decongestant tablets, Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes
  • Vicks Sinex Severe Nasal Spray is HSA and FSA eligible, Check with your provider for more details

$14.97
SALE −$4.01

Mucinex DM Max Liquid Cough & Cold Medicine For Adults, Cold And Flu Medicine for Excess Mucus Relief, Guaifenesin & Dextromethorphan Expectorant & Decongestant for Adults, Dr Recommended, 6.0 Fl Oz

  • COUGH COLD AND FLU MEDICINE FOR ADULTS: Mucinex DM Max expectorant & cough suppressant packs a powerful 1..2.. punch with dextromethorphan and Guaifenesin 400mg extended release, providing you with long-lasting relief from mucus congestion and cough.
  • EXCESS MUCUS RELIEF: Maxium strength multi-symptom relief. Mucinex DM Max is clinically proven to last up to 4hrs and provide relief for chest congestion and make coughs more productive.
  • EXPECTORANTS AND DECONGESTANTS FOR ADULTS: Mucinex DM Max helps clear lungs of excess mucus and phlegm to help make every day a breath of fresh air. Say goodbye to chest congestion and cough, say hello to excess mucus relief!
  • EXTENDED RELEASE GUAIFENESIN: Experience 4hr relief with Mucinex DM Max extended-release 400mg guaifenesin and 20mg dextromethorphan HBr in an easier to swallow liquid format.
  • TRUSTED BRAND: Mucinex is the #1 Cough & Cold Brand Doctor's Trust* and is also the #1 Pharmacist Recommended Brand. Don't be fooled by cheap imitations get the brand that doctors trust and recommend!
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$13.97

Puregen Labs Nasal Decongestant PE 100 Tablets | Phenylephrine HCl 10 mg Tablets | Maximum Strength | Non Drowsy Nasal & Sinus Congestion Relief Due to Cold or Allergies (1)

  • ✅ ACTIVE INGREDIENT: The active ingredient in this Maximum Strength Nasal Decongestant PE is phenylephrine HCl 10 mg. Compares to the active ingredient in major brands.
  • ✅ NASAL DECONGESTANT: Puregen Labs Phenylephrine HCl provides maximum strength, non-drowsy relief for nasal and sinus congestion, sinus pressure due to the common cold, hay fever or other upper respiratory allergies.
  • ✅ NON-DROWSY FORMULA: Puregen Labs Decongestant PE can be taken any time of day including the morning or daytime without making you drowsy. The smart choice for when you cannot miss work, school, or an important event.
  • ✅ Easy-to-Swallow Tablets – These tablets are very small and easy to swallow. For exact size please refer to the pictures. Please follow the directions closely to ensure proper safety and use.
  • ✅ QUALITY YOU CAN TRUST: Our formula is GLUTEN-FREE, GMO-FREE, Vegetarian friendly and made in a facility following strict GMP guidelines to ensure safety and quality.

$8.95

Last update on 2025-05-04 / Affiliate links / Images from Amazon Product Advertising API