Spider spray is an essential tool for anyone looking to keep their home free from unwanted arachnids. In 2025, the market offers a variety of effective spider sprays that not only eliminate spiders but also deter them from returning. These products are formulated with potent ingredients that target spiders specifically, ensuring a thorough and lasting solution. Whether you prefer natural options or chemical-based sprays, there’s a top choice for every need. Discover the best spider sprays available to maintain a spider-free environment in your home.
SALE
−$2.50
Ortho Home Defense Insect Killer for Indoor & Perimeter2 with Comfort Wand, Controls Ants, Roaches, and Spiders, 1.1 gal
- Ortho Home Defense Insect Killer for Indoor & Perimeter2 is a bug killer spray that kills the toughest home invading insects, including ants, cockroaches, spiders, fleas, ticks, scorpions, earwigs, silverfish, and periodical cicadas (as listed)
- Provides a long-lasting bug barrier of up to 12 month protection (against ants, roaches, and spiders indoors on non-porous surfaces)
- Apply this pesticide anytime as a preventative treatment or after you see evidence of insect activity
- Use this pest control spray with confidence indoors (kitchens, bathrooms, doors and windows) and outdoors (perimeter of foundations, patios and decks, garages) wherever insects are a recurring problem
- The easy-to-use continuous spray Comfort Wand helps you control insects easily and accurately without any bending, pumping, or hand-fatigue
$17.99
SALE
−$3.03
Wet & Forget 803064 Miss Muffet's Revenge Indoor and Outdoor Spider Killer with Attached Sprayer, 64 Fluid Ounces, Ready to Use
- Kills spiders and creates a barrier inside and outside the home to keep them away for up to 12 months with just one application
- Attached sprayer for quick and easy application with a spray range of up to 10 feet for those hard to reach places
- Treat all areas were spiders are found, spray until wet but not soaking and for long lasting results leave spray undisturbed
- Apply in calm weather where rain is not expected for 24hrs and allow to dry completely before entering treated area
- Miss Muffet's Revenge has unlimited shelf life, is ready to use, and especially formulated for all spiders except Black Widow and Brown Recluse
$21.96
SALE
−$0.71
Hot Shot Ant, Roach & Spider Killer, Kills Insects Indoors and Outdoors, Kills Roaches and Listed Ants on Contact, Insecticide Spray, 17.5 Ounce (Crisp Linen)
- FAST KNOCKDOWN: Kills listed insects on contact* and keeps killing up to 3 months.**
- KILLS INSECTS INDOORS: Hot Shot Ant, Roach & Spider Killer kills ants, cockroaches, spiders, fleas, silverfish, firebrats, crickets, Asian ladybeetles, carpet beetles, waterbugs, palmetto bugs and stink bugs indoors.
- KILLS INSECTS OUTDOORS: This product kills ants, cockroaches, spiders, fleas, crickets, Asian ladybeetles, stink bugs, palmetto bugs and waterbugs outdoors.
- CRISP LINEN SCENT: Use Hot Shot Ant, Roach & Spider Killer to kill insects while leaving behind a crisp linen scent.
- NO OILY RESIDUE: Spray surface until damp; this product leaves no oily residue behind.
$4.68
Mighty Mint - 16oz Spider Repellent Peppermint Oil - Natural Spray for Spiders and Insects - Killer + Deterrent
- Safe when used as directed
- Extra Concentrated for Long-Lasting Protection
- Natural Ingredients Proven Effective in the Real World
- Active Ingredient: Pure Origin Peppermint Essential Oil
- Large 16oz Bottle
$19.95
SALE
−$1.90
Mighty Mint 16 oz Peppermint Oil Insect & Pest Spray - for Spiders, Ants, and More
- Easy Application and Clean Up
- Safe When Used as Directed
- Extra Concentrated for Long-Lasting Protection
- Natural Ingredients Proven Effective in the Real World
- Powerful US Peppermint Oil
$17.08
SALE
−$3.17
Ortho Home Defense Max Indoor Insect Barrier with Extended Reach Comfort Wand, Kills Ants, Roaches, Spiders, Fleas and Ticks, 1 gal.
- Ortho Home Defense Max Indoor Insect Barrier kills and prevents insects inside your home (12-month control for ants, roaches & spiders indoors on non-porous surfaces)
- KILL LISTED INSECTS FAST: Kills all common household bugs like ants, cockroaches, spiders, fleas, ticks, scorpions, beetles, earwigs, silverfish, centipedes, millipedes, and other listed insects
- INDOOR USE: Apply wherever insects are: in kitchens, bathrooms, basements, around doors and windows; spray the hard to reach places where bugs are a recurring problem
- USE WITH CONFIDENCE: Dries up to 30% faster (vs. other Ortho formulas) and leaves no stains or fumes; people and pets may enter treated areas after spray has dried
- EASY TO APPLY: Extended Reach Comfort Wand, now with 2X the reach (vs. other Ortho Comfort Wands) helps reduce back bending and hand fatigue with its one-touch continuous stream delivery — no pumping required
$19.82
Mighty Mint Gallon (128 oz) Insect and Pest Control Peppermint Oil - Natural Spray for Spiders, Ants, and More
- Safe when used as directed
- Extra Concentrated for Long-Lasting Protection
- Natural Ingredients Proven Effective in the Real World
- Large 1 Gallon Container
- Powerful Essential Oil
$35.98
Spectracide Bug Stop Home Barrier, Kills Ants, Roaches and Spiders On Contact, Indoor and Outdoor Insect Control, 32 fl Ounce Ready-To-Use Spray
- Provides insect protection for 9 months
- Ready to use formula
- Available in a 32 ounce size
$4.96
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API