Weed killer spray is an essential tool for maintaining a healthy garden and lawn, especially in 2025 when effective solutions are more important than ever. The market is flooded with options, but the best products stand out for their effectiveness, safety, and ease of use. From natural herbicides to powerful chemical formulations, these top-rated weed killer sprays can help you tackle stubborn weeds while promoting the growth of your desired plants. Whether you're a seasoned gardener or a novice, finding the right weed killer spray can make all the difference in achieving a lush, weed-free landscape.
SALE
−$3.52
Roundup Weed and Grass Killer₄ with Pump 'N Go 2 Sprayer, Use in and Around Flower Beds, Trees & More, 1.33 gal.
- Roundup Weed & Grass Killer₄ kills tough weeds and grasses to the root, including dandelion, crabgrass, poison ivy, clover (red & white), spotted spurge, and other broadleaf weeds
- It is rainproof in as fast as 30 minutes and produces visible results in hours
- Allows for planting 1 to 30 days after application (see booklet for details)
- Use in or around flower beds and perennial landscape plants, around trees and shrubs, on patios, walkways, and driveways, gravel, or mulch beds, along fences and foundations, and edging around foundations and retaining walls
- The Pump ‘N Go 2 Sprayer with an extendable wand provides up to 10 minutes of continuous spray and provides greater accuracy without bending over
$21.97
SALE
−$5.73
Spectracide Weed and Grass Killer, Pack of 1
- Comes in 1 gallon jug with AccuShot sprayer
- AccuShot sprayer works on battery power and constantly sprays with no pumping required
- You'll see visible results in as little as three hours
- Kills the root of bothersome weeds and grasses
- Works great around trees, shrubs, in flower beds, on patios and walkways, and you can even replant flowers, trees and shrubs in the same weekend
$18.46
SALE
−$1.83
Spectracide Weed & Grass Killer 2, Use On Driveways, Walkways and Around Trees and Flower Beds, 32 fl Ounce Spray
- KILLS WEEDS AND GRASSES: Use on driveways and walkways, and around fences, trees, flower beds, shrubs and other areas in your yard
- FAST-ACTING FORMULA: Visible results as fast as 3 hours – replant new flowers, trees and shrubs the same weekend
- RAINFAST: Rainfall or watering 15 minutes after application will not wash away effectiveness
- READY TO USE: Spray to completely cover the leaves of the target vegetation
- KILLS THE ROOT: Kills weeds and grasses as listed
$4.96
SALE
−$2.32
Ortho WeedClear Weed Killer for Lawns with Comfort Wand, Kills More than 250 Weeds including Dandelion and Clover, 1 gal
- Use Ortho WeedClear Weed Killer for Lawns to kill weeds down to the root without harming your lawn (when used as directed)
- This lawn weed killer kills over 250 common lawn weeds, including dandelions, clover, poison ivy, chickweed, and dollarweed (see product label for complete weed list)
- Contains three proven weed killers that target lawn weeds without harming label listed lawns (when used as directed)
- Visible results in hours; rainproof in 1 hour upon drying; people and pets may enter the treated area after the spray has dried
- Comes with the continuous spray Comfort Wand applicator, which allows for precise spray control—no pumping required
$17.67
Spruce Weed Killer Spray - Snap & Spray Weed & Grass Killer₂ Powered Starter Kit - Reusable Sprayer with Wand for Spot-Treating Driveways, Gardens & More (64 Oz Bottle)
- Worry-Free Formula - Spruce is safe to use around people and pets when used as directed, and one bottle can treat up to 400 weeds. The versatile weed killer spray is made with water, essential oils and surfactant.
- Visible Results in One Hour - Spruce is designed to break down plant cells so weeds die from dehydration. The hardworking weed spray can kill all types of broadleaf and grassy weeds including dandelions, large crabgrass, white clover, dollarweed and morning glory vines.
- Great For - This formula is a great weed and grass killer spray for mulch beds, driveways, pavers and walkways. It can also be used for spot-treating weeds in landscape areas, raised beds and gardens. For best results, use at the first sign of weed growth.
- How to Use - Slide switch to 'Unlocked' position and hold paddle until product sprays. Hold the weed sprayer nozzle twelve inches from weeds, and spray the entire plant until it is thoroughly wet. After use, slide switch to 'Locked' position.
- The Snap and Spray Kit - This simplified grass and weed killer comes with a reusable wand and 64 oz bottle of our no-mix, no-pour, no-mess herbicide. Be sure to stock up on refills, and try EZ-AIM for tough cracks and edges.
$39.97
SALE
−$12.50
Roundup Dual Action 365 Weed & Grass Killer Plus 12 Month Preventer with Comfort Wand, Kills & Prevents for up to 1 Year, 1 gal.
- Roundup Dual Action 365 Weed & Grass Killer Plus 12 Month Preventer with Comfort Wand provides one-step weed protection for up to 12 months
- Our weed control kills and prevents many types of tough weeds and grasses for up to 12 months, including clover, dandelion, large and smooth crabgrass, poison ivy, and other broadleaf weeds, grassy weeds and brush
- Roundup Dual Action 365 Weed & Grass Killer Plus 12 Month Preventer with Comfort Wand is rainproof in as fast as 30 minutes and produces visible results in hours
- Use this weed preventer where you want to kill existing weeds AND prevent new weeds for up to 1 year, such as cracks and crevices in driveways, sidewalks, and walkways, patios, paths, and under decks, gravel areas, and other non-lawn areas
- The easy-to-use Comfort Wand with one-touch continuous spray means no more tired, aching hands
$37.49
SALE
−$1.43
Ortho WeedClear Lawn Weed Killer Ready-To-Spray, Kills Crabgrass, Dandelion and Clover, 32 oz.
- Kill weeds in your lawn, including dandelion, chickweed, clover, crabgrass and foxtail with the Ortho WeedClear Lawn Weed Killer Ready-to-Spray
- This fasting-acting weed control kills listed weeds to the root and gets results with 1 application
- Kills weeds not the lawn when used as directed - use on lawn grasses including Bermudagrass, Buffalograss, Fescues, Kentucky Bluegrass, Ryegrass and Zoysiagrass
- Apply to weeds that are young and actively growing by connecting your garden hose to the sprayer, sliding the switch to "ON" and spraying evenly until the lawn is wet
- This 32 oz. container of Ortho WeedClear Lawn Weed Killer Ready-to-Spray treats up to 5,000 sq. ft.
$12.56
Spectracide Weed Stop For Lawns Plus Crabgrass Killer, Ready-To-Use Spray Kills More Than 470 Types Of Weeds As Listed Including Dandelion, Chickweed, Clover, Crabgrass And Yellow Nutsedge, 32 Ounces
- Item Package Dimension: 11.6099999881578L x 6.4599999934108W x 2.7599999971848H inches
- Item Package Weight - 2.29060290218 Pounds
- Item Package Quantity - 1
- Product Type - WEED MOSS CONTROL AGENT
$6.24
SALE
−$1.82
Ortho GroundClear Weed and Grass Killer with Comfort Wand, Kills Dandelions, Chickweed, Crabgrass, Moss and More in Patios and Landscapes, OMRI Listed, 1 gal.
- Ortho GroundClear Weed & Grass Killer kills all types of weeds and grasses, including dandelions, chickweed, spotted spurge, moss, crabgrass and perennial ryegrass
- This fast-acting weed control product absorbs on contact to produce results in just 15 minutes, and is rainproof in 2 hours (upon drying)
- This weed and grass killer controls weeds in, on and around walkways and driveways, under trees, and in landscape beds; not for use on lawns or grasses you like
- Apply when weeds are small, actively growing and not wet from rain, dew or irrigation
- This 1 gal. container of Ortho GroundClear Weed & Grass Killer includes a Comfort Wand applicator to accurately target weeds you want to kill
$21.17
SALE
−$8.10
Ortho GroundClear Year Long Vegetation Killer - With Continuous Spray Comfort Wand, Visible Results in 1 Hour, Kills Weeds and Grasses to the Root, Up to 1 Year of Weed and Grass Control, 1.33 gal.
- Ortho GroundClear Year Long Vegetation Killer with Comfort Wand kills weeds and prevents any re-growth for up to 1 year with a single application
- Fast-acting formula starts working immediately
- Starts to kill weeds and grasses in 1 hour
- Apply to driveways, sidewalks, gravel areas, rock and desert landscapes, under decks, on parking areas, and along fences and curbs
- For the best results, apply using the attached Comfort Wand when weeds are actively growing on sunny days when the temperature is above 60°F
$32.39
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API