Spider killer spray for indoors is essential for maintaining a pest-free home environment. In 2025, several products stand out for their effectiveness, ease of use, and safety for indoor application. These sprays not only eliminate spiders on contact but also provide long-lasting protection against future infestations. With a variety of formulations available, including natural and chemical options, homeowners can choose the best spider killer spray that suits their needs while ensuring a safe living space.
SALE
−$0.71
Hot Shot Ant, Roach & Spider Killer, Kills Insects Indoors and Outdoors, Kills Roaches and Listed Ants on Contact, Insecticide Spray, 17.5 Ounce (Crisp Linen)
- FAST KNOCKDOWN: Kills listed insects on contact* and keeps killing up to 3 months.**
- KILLS INSECTS INDOORS: Hot Shot Ant, Roach & Spider Killer kills ants, cockroaches, spiders, fleas, silverfish, firebrats, crickets, Asian ladybeetles, carpet beetles, waterbugs, palmetto bugs and stink bugs indoors.
- KILLS INSECTS OUTDOORS: This product kills ants, cockroaches, spiders, fleas, crickets, Asian ladybeetles, stink bugs, palmetto bugs and waterbugs outdoors.
- CRISP LINEN SCENT: Use Hot Shot Ant, Roach & Spider Killer to kill insects while leaving behind a crisp linen scent.
- NO OILY RESIDUE: Spray surface until damp; this product leaves no oily residue behind.
$4.68
SALE
−$2.50
Ortho Home Defense Insect Killer for Indoor & Perimeter2 with Comfort Wand, Controls Ants, Roaches, and Spiders, 1.1 gal
- Ortho Home Defense Insect Killer for Indoor & Perimeter2 is a bug killer spray that kills the toughest home invading insects, including ants, cockroaches, spiders, fleas, ticks, scorpions, earwigs, silverfish, and periodical cicadas (as listed)
- Provides a long-lasting bug barrier of up to 12 month protection (against ants, roaches, and spiders indoors on non-porous surfaces)
- Apply this pesticide anytime as a preventative treatment or after you see evidence of insect activity
- Use this pest control spray with confidence indoors (kitchens, bathrooms, doors and windows) and outdoors (perimeter of foundations, patios and decks, garages) wherever insects are a recurring problem
- The easy-to-use continuous spray Comfort Wand helps you control insects easily and accurately without any bending, pumping, or hand-fatigue
$17.99
Spectracide Bug Stop Home Barrier, Kills Ants, Roaches and Spiders On Contact, Indoor and Outdoor Insect Control, 32 fl Ounce Ready-To-Use Spray
- Provides insect protection for 9 months
- Ready to use formula
- Available in a 32 ounce size
$4.96
SALE
−$3.17
Ortho Home Defense Max Indoor Insect Barrier with Extended Reach Comfort Wand, Kills Ants, Roaches, Spiders, Fleas and Ticks, 1 gal.
- Ortho Home Defense Max Indoor Insect Barrier kills and prevents insects inside your home (12-month control for ants, roaches & spiders indoors on non-porous surfaces)
- KILL LISTED INSECTS FAST: Kills all common household bugs like ants, cockroaches, spiders, fleas, ticks, scorpions, beetles, earwigs, silverfish, centipedes, millipedes, and other listed insects
- INDOOR USE: Apply wherever insects are: in kitchens, bathrooms, basements, around doors and windows; spray the hard to reach places where bugs are a recurring problem
- USE WITH CONFIDENCE: Dries up to 30% faster (vs. other Ortho formulas) and leaves no stains or fumes; people and pets may enter treated areas after spray has dried
- EASY TO APPLY: Extended Reach Comfort Wand, now with 2X the reach (vs. other Ortho Comfort Wands) helps reduce back bending and hand fatigue with its one-touch continuous stream delivery — no pumping required
$19.82
TERRO T401SR Indoor and Outdoor Ant Killer Aerosol Spray - Kills Ants, Cockroaches, Crickets, Scorpions, Spiders, and Other Insects - 2 Pack 32 Total Ounces
- 2 bottles included
- Kills ants and other insects on contact
- Kills on contact and continues to kill for up to 6 weeks
- Use as a spot treatment and in cracks and crevices
- 16 oz aerosol can with twist-to-open top
$13.49
SALE
−$1.90
Mighty Mint 16 oz Peppermint Oil Insect & Pest Spray - for Spiders, Ants, and More
- Easy Application and Clean Up
- Safe When Used as Directed
- Extra Concentrated for Long-Lasting Protection
- Natural Ingredients Proven Effective in the Real World
- Powerful US Peppermint Oil
$17.08
SALE
−$3.03
Wet & Forget 803064 Miss Muffet's Revenge Indoor and Outdoor Spider Killer with Attached Sprayer, 64 Fluid Ounces, Ready to Use
- Kills spiders and creates a barrier inside and outside the home to keep them away for up to 12 months with just one application
- Attached sprayer for quick and easy application with a spray range of up to 10 feet for those hard to reach places
- Treat all areas were spiders are found, spray until wet but not soaking and for long lasting results leave spray undisturbed
- Apply in calm weather where rain is not expected for 24hrs and allow to dry completely before entering treated area
- Miss Muffet's Revenge has unlimited shelf life, is ready to use, and especially formulated for all spiders except Black Widow and Brown Recluse
$21.96
Mighty Mint - 16oz Spider Repellent Peppermint Oil - Natural Spray for Spiders and Insects - Killer + Deterrent
- Safe when used as directed
- Extra Concentrated for Long-Lasting Protection
- Natural Ingredients Proven Effective in the Real World
- Active Ingredient: Pure Origin Peppermint Essential Oil
- Large 16oz Bottle
$19.95
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API