Running shoes for knee pain are essential for those looking to maintain an active lifestyle while minimizing discomfort. The right pair can provide the necessary support, cushioning, and stability to alleviate pressure on the knees. In 2025, several models stand out for their innovative designs and technology aimed at reducing knee strain. From brands renowned for their orthopedic features to those that prioritize comfort and performance, these shoes cater to various running styles and preferences. Investing in the best running shoes can make a significant difference in your running experience and overall joint health.
SALE
−$45.00
Brooks Women’s Adrenaline GTS 23 Supportive Running Shoe - Blue Glass/Nile Blue/Marina - 10.5 Medium
- THIS WOMEN’S SHOE IS FOR: The Adrenaline GTS 23 is for runners who need support and want a smooth, reliable ride. This Brooks Adrenaline GTS 23 is a certified PDAC A5500 Diabetic shoe and has been granted the APMA Seal of Acceptance. Predecessor: Adrenaline GTS 22
- GUIDERAILS HOLISTIC SUPPORT SYSTEM: Our unique technology aligns your body in its natural motion path while keeping excess movement in check.
- SOFT, LIGHTWEIGHT CUSHIONING: New midsole features soft and lighter weight DNA LOFT v2 cushioning.
- ENHANCED UPPER: Engineered air mesh upper provides comfort and breathability with 3D Fit Print for added structure.
- TRUSTED, SECURE FIT: Engineered Air Mesh and use of 3D Fit Print to enhance upper and deliver the structure and proven fit the Adrenaline is known for.
$94.95
Dr. Scholl's Knee All-Day Pain Relief Orthotics - Insoles for Immediate and All-Day Knee Pain Relief Including Pain from Osteoarthritis and Runner’s Knee, Size 8-14, 1 Pair, Trim to Fit Inserts
- Clinically proven insoles that help relieve the top 3 sources of knee pain all day: Runner’s Knee Pain, Osteoarthritis Pain and General Knee Pain. Experience immediate & all-day pain relief!
- Immediately treats pain while helping to protect the knee cartiliage and meniscus from shock and strain
- Scientifically designed & engineered to relieve stress & protect against impact
- Absorbs pain-inducing shock at it's source and prevents it from traveling up your leg
- Trim to fit men's shoe sizes 8-14. These insoles can be used in almost any shoe.
$13.37
SALE
−$30.00
Brooks Women’s Ghost 16 Neutral Running Shoe - Peacoat/Raspberry/Apricot - 8 Medium
- THIS WOMEN'S SHOE IS FOR: Runners looking for a smooth ride that won’t distract from the fun of the run. The Ghost 16 offers a refined 3D Fit Print to create a more seamless, secure fit. This Brooks Ghost 16 is a certified PDAC A5500 Diabetic shoe and has been granted the APMA Seal of Acceptance. The Ghost 16 is a certified carbon neutral product. Predecessor: Ghost 15.
- SOFT CUSHIONING: The Ghost 16 offers neutral support while providing soft, nitrogen-infused DNA Loft v3 cushioning to deliver lightweight comfort. Ideal for road running, walking, cross training, the gym or wherever you might want to take them!
- SMOOTH TRANSITIONS: The soft midsole and Segmented Crash Pad promotes an easy flow from landing to toe-off to provide distraction- free cushioning under your feet with every stride.
- BREATHABLE UPPER: Engineered air mesh upper blends stretch and structure with just-right breathability to keep you comfortable.
- ROADTACK RUBBER OUTSOLE: New, do-it-all rubber compound includes recycled silica and is designed to be durable, lightweight, and rebound.
$109.95
ASICS Women's Gel-Venture 8 Running Shoes, 7.5, Black/Ivory
- GEL Technology: Cushioning provides excellent shock absorption
- Re-engineered outsole lugs for better off-road traction:
- Wide fit:
- The heel height is inches and the color is Black/Ivory
Deprecated: preg_replace(): Passing null to parameter #3 ($subject) of type array|string is deprecated in /home/runcloud/webapps/joesitalianfulshear/wp-content/themes/blocksy/aawp/products/custom-table.php on line 139
SALE
−$13.60
Saucony Women's Cohesion 13 Running Shoe, Dusk/Blush, 8
- New versarun cushioning for comfort
- Segmented rubber outsole for a smooth feel
$61.40
NORTIV 8 Women's Walking Shoes Cushion Running Tennis Shoes ActiveFloat Non-Slip Comfortable Breathable Workout Gym Sports Athletic Fashion Sneakers,Size 6.5,Purple,SNWS245W
- Comfort & Shock Absorption: These fashion sneakers boast a plush, high-rebound EVA midsole that cushions each step, alleviating strain on your knees. Feel the softness and shock absorption with these sneakers.
- Traction & Durability: From city streets to running paths, enjoy stability and lasting performance, step after step thanks to the robust rubber outsole.
- Breathability & Coolness: The soft and light woven mesh upper is gentle against your skin, ensuring your feet stay cool, while also boasting effortless cleaning and upkeep.
- Support & Stability: Designed with a TPU film, these athletic shoes offer increased foot support. Experience a secure fit that reduces the risk of injury during workouts or daily activities.
- Versatile Wear: Whether you're walking, running, hitting the gym, walking the dog, or commuting to work, these women's walking sneakers are your reliable companion.
$51.99
SALE
−$15.05
ASICS Women's Gel-Excite Trail 2 Running Shoes, 7.5, Birch/Dolphin Grey
- Durable and breathable no-sew mesh upper
- AMPLIFOAM PLUS cushioning: Helps to improve durability and create a more flexible feel at footstrike
- Rearfoot GEL technology: Improves impact absorption and creates a softer feeling at footstrike
- OrthoLite sockliner: Provides soft step-in comfort
- Trail-specific outsole: Helps provide better grip on off-road surfaces
$59.95
SALE
−$10.04
New Balance womens Fresh Foam Roav V1 Running Shoe Sneaker, Black/Light Aluminum, 6.5 US
- Truly Unique: The New Balance Fresh Foam Roav v1 running shoes are the ultimate in casual athletic style. Pairing a bold, attractive look with plush comfort, these cushioned running shoes are in a league of their own.
- Fresh Foam Midsole: Feel like you're running or walking in the clouds. The first of three proprietary technologies in this athletic shoe, Fresh Foam midsole cushioning is precision engineered to deliver an ultra-cushioned, lightweight ride.
- NDurance Outsole: Step up your game without wearing out your favorite running shoes. Ndurance rubber outsole technology provides superior durability in high-wear areas to help get more out of the shoes.
- Ultra Heel: These neutral running shoes boast a head-turning heel that performs as well as it looks. The Ultra Heel design hugs the back of the foot for a snug, supportive fit. This unique heel works alongside the bootie upper for all-day comfort.
- 8mm Drop: These lightweight shoes feature a heel-to-toe drop of approximately 8mm. Due to variances created during development and manufacturing processes, references to 8mm are approximate.
$74.95
Brooks Women’s Glycerin 21 Neutral Running Shoe - Lavender/Black/Copper - 9.5 Medium
- THIS WOMEN'S SHOE IS FOR: The Glycerin 21 is perfect for runners seeking super-soft cushioning for supreme comfort. The plush internal fit and soft, stable transitions keep runners surrounded by super-softness. This Brooks Glycerin 21 has been granted the APMA Seal of Acceptance.
- NEUTRAL SUPPORT: Provides neutral support while offering the maximum amount of cushioning. Ideal for road running, cross training, the gym or wherever you might want to take them! Predecessor: Glycerin 20. Look for the Brooks Glycerin GTS 21 for the same style with added support.
- SUPREME SOFTNESS: The ultimate in softness with even more super-soft nitrogen-infused DNA Loft v3 cushioning, optimized to be lightweight, responsive, and durable for plush comfort.
- PLUSH IMPROVED FIT: The plush feel of an internal stretch bootie surrounds your foot and moves and expands with your stride. The newly engineered warp knit upper is breathable and allows for a flexible, accommodating fit while staying soft against the foot.
- SMOOTH, STABLE TRANSITIONS: The broad platform stabilizes your foot and promotes smooth heel-to-toe transitions for a supremely soft on-the-run experience.
$192.57
SALE
−$60.00
Brooks Women’s Glycerin Stealthfit 21 Neutral Running Shoe - Black/Cream/Biscuit - 9 Medium
- THIS WOMEN’S SHOE IS FOR: The Glycerin Stealthfit 21 is for runners who want a snug, close-to-foot fit and supreme softness in every step — so they can get lost in the comfortable ride and run distraction-free. This Brooks Glycerin Stealthfit 21 has been granted the APMA Seal of Acceptance. Predecessor: Brooks Glycerin Stealthfit 20.
- SUPREME SOFTNESS: Now with even more super-soft nitrogen-infused DNA LOFT v3 cushioning that is optimized to be lightweight, responsive, and durable with plush comfort.
- SECURE, ADAPTABLE FIT: Updated flat knit upper Stealthfit construction offers a blend of stretch and compression for a closer fit which provides seamless structure, breathability and adapts to the movements of your foot.
- SMOOTH, STABLE TRANSITIONS: The broad platform stabilizes your foot and promotes smooth heel-to-toe transitions for a supremely soft on-the-run experience.
- BREATHABILITY: Flat Knit upper provides a seamless fit that allows for maximum breathability to keep your feet comfortably cool.
$99.95
Last update on 2025-05-03 / Affiliate links / Images from Amazon Product Advertising API