Preservative free eye drops are essential for those seeking relief from dry eyes without the irritation that preservatives can cause. In 2025, the market offers a variety of top-rated options that cater to different needs, ensuring comfort and hydration for all users. These eye drops are formulated to provide long-lasting moisture and protection, making them ideal for sensitive eyes or frequent use. With advancements in technology and formulation, the best preservative free eye drops are designed to deliver effective relief while maintaining the integrity of the eye's natural environment.
SALE
−$5.69
Refresh Plus Lubricant Eye Drops, Preservative-Free, 0.01 Fl Oz Single-Use Containers, 50 Count, Packaging May Vary
- Original strength, preservative-free formula
- Relieves mild symptoms of eye dryness
- Instantly moisturizes and lubricates
- Designed to act like your own natural tears
- Great for sensitive eyes
$16.30
SALE
−$14.55
Systane COMPLETE PF Multi-Dose Preservative Free Dry Eye Drops 0.34 Fl Oz, 2 count (pack of 1) (Packaging may vary)
- Fast acting hydration for sensitive eyes
- Preservative free tear evaporation protection
- Nano droplets for better coverage
$20.44
SALE
−$9.54
Systane Ultra Multi-Dose Preservative-Free Eye Drops Twin Pack (2x10ml)
- Preservative-Free Lubricant Eye Drops
- Fast-Acting Hydration and lasting dry eye relief
- Moisture rich formula eye drops for sensitive eyes
- Tear evaporation protection for high-performance dry eye symptom relief that lasts
$17.45
SALE
−$1.48
Systane Hydration Multi-Dose Preservative-Free Eye Drops Dry Eye Relief Twin Pack (2x10ml)
- Hydrates fast and provides long-lasting relief for dry eyes
- Preservative free eye drops
- Contains hyaluronate for advanced hydration
- Safe for use with all contact lenses
- Extra moisturizing eye drops for sensitive eyes
$20.49
SALE
−$6.27
iVIZIA Sterile Lubricant Eye Drops for Dry Eyes, Preservative-Free, Moisturizing, Dry Eye Relief, Contact Lens Friendly, 0.33 fl oz Bottle
- iVIZIA Sterile Lubricant Eye Drops for Dry Eyes, Preservative-Free, Moisturizing, Dry Eye Relief, Contact Lens Friendly, 0.33 fl oz bottle.
- Unique Formulation: Hydrating polymers form a protective matrix, moisturizing Hyaluronic Acid holds up to 1000x its weight in moisture, and Trehalose (synthetic ingredient also found in desert plants).
- Free of Irritating Preservatives: Sterile, safe for use with contact lenses
- Patented ABAK Bottle: preservative-free, dispenses drop-by-drop, and does not stream. The ergonomic bottle is easy to open, easy to hold and squeeze.
- iVIZIA – We See a Better Way: for healthy, comfortable eyes
$10.99
SALE
−$0.99
Biotrue Hydration Boost Eye Drops, Preservative Free, Soft Contact Lens Friendly for Irritated and Dry Eyes from Bausch + Lomb, Naturally Inspired, 0.33 FL OZ (10 mL)
- NATURALLY INSPIRED INGREDIENTS: Biotrue Hydration Boost Eye Drops are enhanced with HA (Hyaluronan), Antioxidant, and Electrolyte and provide instant moisture for dry eyes.
- CONTACT LENS FRIENDLY: Biotrue Hydration Boost Eye Drops can be applied while wearing soft contact lenses.
- INSTANT MOISTURE: For dry, irritated eyes due to screen and environmental stressors.
- BIOTRUE EYE DROPS: Not only are the Hydration Boost Eye Drops free of preservatives but they are also pH balanced.
- EYE DROPS and MORE: Bausch and Lomb makes eye care products you can trust, from contact lens solution to eye drops, vitamins, and ointments to help your eyes feel moisturized and protected.
$12.00
SALE
−$9.11
Refresh Plus Lubricant Eye Drops Preservative-Free Tears, 0.01 fl oz (0.4 mL), 70 Single-Use Containers
- Original strength, preservative-free formula
- Relieves mild symptoms of eye dryness
- Instantly moisturizes and lubricates
- Designed to act like your own natural tears
- Great for sensitive eyes
$21.88
SALE
−$3.65
TheraTears Dry Eye Therapy Lubricating Eye Drops for Dry Eyes, Preservative Free eye drops, 30 Single-Use Vials
- TheraTears Dry Eye Therapy Lubricant Eye Drops, Preservative Free, provide immediate, long-lasting relief of dry eye symptoms
- Discover TheraTears eye drops, one-of-a-kind silky hydration for dry eyes
- TheraTears Dry Eye lubricating eye drops contain the 5 vital electrolytes found in natural tears
- TheraTears corrects the salt imbalance that can cause dry eye symptoms
- Preservative free for sensitive eyes; the single-use vials come in a foil pouch to ensure freshness
$9.34
Refresh Tears PF Preservative-Free Artificial Tears Lubricant Eye Drops, 0.33 fl oz (10 mL)
- ORIGINAL STRENGTH: Provides temporary relief for mild, occasional dry eye symptoms
- FAST-ACTING: Instantly lubricates and moisturizes
- PRESERVATIVE-FREE: Great for sensitive eyes
- SOFT SQUEEZE MULTIDOSE BOTTLE: Features a double lockout system that keeps drops sterile
- TRUSTED: From the #1 doctor-recommended preservative-free brand with over 35 years of experience (Data on file, AbbVie, Inc. REF113774)
$13.38
SALE
−$8.11
Refresh RELIEVA Preservative-Free Tears Lubricant Eye Drops, 0.33 fl oz (10 mL)
- Innovative, preservative-free formula in a multidose bottle
- Relieves discomfort due to dry, irritated eyes
- Prevents further irritation
- Hydrocell technology enables hydration and maintains the volume of cells on the eye's surface
- Patented multidose bottle with a double locked system keeps drops sterile
$14.88
Last update on 2025-05-03 / Affiliate links / Images from Amazon Product Advertising API