Pest control spray is an essential tool for maintaining a pest-free environment in homes and gardens. In 2025, the market offers a variety of effective options that cater to different pest problems, from ants and roaches to mosquitoes and termites. These sprays are formulated with advanced ingredients that ensure quick action and long-lasting protection, making them a favorite among homeowners. Whether you prefer natural solutions or chemical formulations, there’s a pest control spray that fits your needs. Explore the top choices to find the best solution for your pest issues.
SALE
−$2.50
Ortho Home Defense Insect Killer for Indoor & Perimeter2 with Comfort Wand, Controls Ants, Roaches, and Spiders, 1.1 gal
- Ortho Home Defense Insect Killer for Indoor & Perimeter2 is a bug killer spray that kills the toughest home invading insects, including ants, cockroaches, spiders, fleas, ticks, scorpions, earwigs, silverfish, and periodical cicadas (as listed)
- Provides a long-lasting bug barrier of up to 12 month protection (against ants, roaches, and spiders indoors on non-porous surfaces)
- Apply this pesticide anytime as a preventative treatment or after you see evidence of insect activity
- Use this pest control spray with confidence indoors (kitchens, bathrooms, doors and windows) and outdoors (perimeter of foundations, patios and decks, garages) wherever insects are a recurring problem
- The easy-to-use continuous spray Comfort Wand helps you control insects easily and accurately without any bending, pumping, or hand-fatigue
$17.99
SALE
−$3.17
Ortho Home Defense Max Indoor Insect Barrier with Extended Reach Comfort Wand, Kills Ants, Roaches, Spiders, Fleas and Ticks, 1 gal.
- Ortho Home Defense Max Indoor Insect Barrier kills and prevents insects inside your home (12-month control for ants, roaches & spiders indoors on non-porous surfaces)
- KILL LISTED INSECTS FAST: Kills all common household bugs like ants, cockroaches, spiders, fleas, ticks, scorpions, beetles, earwigs, silverfish, centipedes, millipedes, and other listed insects
- INDOOR USE: Apply wherever insects are: in kitchens, bathrooms, basements, around doors and windows; spray the hard to reach places where bugs are a recurring problem
- USE WITH CONFIDENCE: Dries up to 30% faster (vs. other Ortho formulas) and leaves no stains or fumes; people and pets may enter treated areas after spray has dried
- EASY TO APPLY: Extended Reach Comfort Wand, now with 2X the reach (vs. other Ortho Comfort Wands) helps reduce back bending and hand fatigue with its one-touch continuous stream delivery — no pumping required
$19.82
SALE
−$5.31
Demand CS Insecticide - Contains iCAP Technology for Long-Lasting Pest Control, 8-oz. Sprayable Insecticide, Effective Against Over 30 Pests, Formulated for Indoor & Outdoor Use
- Broad-Spectrum Pest Control: Targets more than 30 common pests including mosquitoes, spiders, ants, flies, fleas and ticks with the powerful insecticidal properties of the active ingredient lambda-cyhalothrin.
- Formulated with iCAP Technology: This sprayable insecticide concentrate contains multiple-sized microcaps with controlled release for immediate and long-term control of insect pests. The microcapsules adhere to insects, enabling the efficient transfer of the active ingredient, so pests are controlled for up to 90 days.
- Durable Under Extreme Conditions: Formulation remains intact under heat and other environmental pressures. The smooth outer shell of the microcap protects the active ingredient from harsh conditions like sunlight, precipitation, and pH extremes, ensuring robust performance outdoors.
- Easy-Mix Formula: This insecticide concentrate is easily mixed with water. For optimal results, use between 0.2-0.8 fluid ounces of the insecticide concentrate per gallon of water.
$33.19
SALE
−$1.90
Mighty Mint 16 oz Peppermint Oil Insect & Pest Spray - for Spiders, Ants, and More
- Easy Application and Clean Up
- Safe When Used as Directed
- Extra Concentrated for Long-Lasting Protection
- Natural Ingredients Proven Effective in the Real World
- Powerful US Peppermint Oil
$17.08
Mighty Mint Gallon (128 oz) Insect and Pest Control Peppermint Oil - Natural Spray for Spiders, Ants, and More
- Safe when used as directed
- Extra Concentrated for Long-Lasting Protection
- Natural Ingredients Proven Effective in the Real World
- Large 1 Gallon Container
- Powerful Essential Oil
$35.98
SALE
−$4.00
Pest Control, Mice Repellent, Mouse Repellant Indoor, Extra-Strength Peppermint to Repel Rat, Ant, Roach, Mosquito,Moth and More, RV Rat Repellent Indoor and Outdoor, Mice Control-1P
- 【POWERFUL PEST CONTROL】This pest control spray is formulated with natural essential ingredients, effectively targets and repels a variety of pest such as rodents, cockroaches, ants, spiders, mosquitoes, fleas and ticks. The strong minty scent irritate pest' sensory systems, deterring them from entering your home and surrounding areas.
- 【LONG-LASTING INDOOR & OUTDOOR PROTECTION】This pest deterrent offers protection that lasts up to 3 months with each application. The invisible and long-lasting barrier ensures pest are kept at bay both indoors and outdoors, effectively stoppping rodents chewing on wires, spiders webbing in ceilings, cockroaches crawling in kitchen and more pest activities.
- 【SAFE & ACTIVE FORMULA AGAINST PEST】Our peppermint repellent spray for pest uses a natural, plant-based formula that is safe for families and pets when used as directed. Enjoy comprehensive pest defense without worrying about home safety.
- 【EASY FOR USE】Simply press the spray handle and apply the repellent to areas where pest are known to appear or hide. The fast-drying formula leaves no stains and can be applied quickly to maintain a clean space without pest.
- 【VERSATILE USE PEST REPELLENT】The powerful and natural mint pest deterrent is designed for indoor and outdoor areas use, including living room, kitchens, attic, basements, garages, patios, and gardens. Ensure protection wherever pest problems may occur.
$25.99
SALE
−$2.53
Ortho Home Defense Insect Killer for Indoor and Perimeter Refill2, Controls Ants, Roaches, Spiders and More, 1 gal
- Ortho Home Defense Insect Killer for Indoor & Perimeter Refill2 kills the toughest home-invading insects, including ants, cockroaches, spiders, fleas, ticks, scorpions, earwigs, silverfish and periodical cicadas (as listed)
- This insect killer spray provides a long-lasting bug barrier of up to 12 month protection against ants, roaches and spiders indoors on non-porous surfaces
- Use this pest control spray indoors in kitchens and bathrooms or around doors and windows, and outdoors to the perimeter of foundations, patios, decks, garages or wherever insects are a recurring problem
- Apply this bug killer anytime as a preventative treatment or after you see evidence of insect activity
- This 1 gal. Ortho Home Defense Insect Killer for Indoor & Perimeter Refill2 allows you to reuse your Comfort Wand from its original container
$9.96
STEM Kills Ants, Roaches And Flies: Plant-Based Active Ingredient Bug Spray, Botanical Insecticide For Indoor And Outdoor Use; 12 fl oz (Pack Of 1)
- Bug spray that quickly kills ants, roaches and flies
- Plant-based active ingredient bug killer safe for use around people and pets (when used as directed)
- Entomologist tested bug spray made with botanical extracts to kill bugs; with a fresh scent and no added dye, fragrance, or harsh chemical odors
- Bug killer for indoor and outdoor use, wherever bugs try to bother you
- Rooted in Nature, Optimized by Science?
$6.97
SALE
−$11.53
Spectracide Bug Stop Home Barrier, Kills Ants, Roaches and Spiders On Contact, Indoor and Outdoor Insect Control, 1.33 Gallon (RTU Accushot Spray), Plain
- CONTINUOUS POWER SPRAYER WITH EXTENDABLE WAND: The AccuShot wand reduces hand fatigue with a continuous action power sprayer, meaning no pumping or squeezing, just press to spray. This battery powered wand is also extendable for improved accuracy. Comfort – Power – Precision.
- KILLS ON CONTACT: This product kills multiple types of insects indoors and outdoors, including ants, roaches, spiders, fleas and ticks. See label for full list of insects.
- FAST-ACTING: This fast-killing product kills on contact to provide economical do-it-yourself pest control, killing bugs you see and the bugs you don’t see.
- USE INDOORS AND OUTDOORS: Spectracide Bug Stop Home Barrier is an indoor plus home barrier insect treatment. Use indoors in cracks and crevices, along baseboards, under sinks, behind stoves and refrigerators and anywhere insects may hide. Use outdoors on the surfaces of screens, doors and window frames, porches, patios, buildings or wherever insect may enter.
- CLEAR FORMULA: The non-staining, clear formula leaves no oily residue. This unscented, water-based product also leaves no lingering odor.
$14.46
SALE
−$4.50
Atticus Talak 7.9% Indoor/Outdoor Insect Control - Bifenthrin Concentrate (1 GAL)
- VERSATILE PARTNER, PROVEN EFFECTIVENESS: Talak 7.9% Indoor/Outdoor Insect Control contains 7.9% bifenthrin. Bifenthrin has been a trusted insecticide delivering reliable insect control for more than 35 years and may be used in a variety of indoor and outdoor settings.
- ONE SOLUTION COVERS IT ALL: Our water-based formula can be used indoors and outdoors and dries clear, leaves no residue, and is odor-free. This hard-working insecticide may be applied to lawns, landscapes, outside surfaces such as porches, patio and hardscape cracks/crevices, and window frames as well as interior baseboards, cabinets, sinks, and interior plantscapes. Plus, Talak 7.9 F does not cause phytotoxicity, which means it won’t damage your plants.
- BROAD-SPECTRUM INSECT KILL: Talak 7.9% Indoor/Outdoor Insect Control targets more than 75 indoor and outdoor pests including ants, fleas, ticks, spiders, scorpions, mosquitoes, roaches, and wasps. Talak may also be applied as a mound drench to eliminate dangerous fire ant colonies. See the label for application instructions and complete insect control list.
- GET THE WATER-BASED ADVANTAGE: Getting rid of bugs shouldn’t come with stains, spots, and scents. Our water-based formula can be used indoors and outdoors and dries clear, leaves no residue, and is odor-free. Plus, Talak 7.9 F does not cause phytotoxicity, which means it won’t damage your plants.
- KILLS ON CONTACT, WORKS UP TO 3 MONTHS: Expect fast results with an active ingredient that gets right to work. Talak 7.9% Indoor/Outdoor Insect Control kills pests on contact and lasts up to 3 months for continued insect control. Simply dilute with the appropriate water amount per intended use and application volume as listed on the label. Once sprays have dried completely, people and pets are free to re-enter the area. Read product label for application rates, dilution rates, and instructions.
$48.49
Last update on 2025-05-01 / Affiliate links / Images from Amazon Product Advertising API