Pain reliever for toothache can provide much-needed relief when dental discomfort strikes. In 2025, several options stand out for their effectiveness and accessibility. Over-the-counter medications like ibuprofen and acetaminophen are popular choices, while topical treatments containing benzocaine can numb the affected area quickly. Natural remedies, such as clove oil and saltwater rinses, also offer soothing effects. For those seeking alternative solutions, homeopathic options and herbal supplements are gaining traction. Always consult with a healthcare professional before starting any new treatment to ensure it’s appropriate for your specific situation.
SALE
−$1.46
DenTek Instant Oral Pain Relief Maximum Strength Kit for Toothaches | 50 Count
- DenTek Instant Pain Relief, Advanced Kit gives instant and precise relief from oral pain and toothaches
- Ergonomic handle to reach any area of the mouth gives simple, no-fingers no-mess, relief
- Fresh Mint flavored Benzocaine relieves tooth pain, sore gums and mouth sores
- Maximum strength pain reliever
- 50 disposable applicators easily slide into the handle for a sanitary way to relieve tooth pain
$8.49
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−$2.51
Orajel 4X for Toothache & Gum Pain: Severe Cream Tube 0.33oz- From Oral Pain Relief Brand
- INSTANT PAIN RELIEF: Instant pain relief with Orajel’s unique 4X clinical strength formula to help relieve pain of the tooth and gums
- 4X ACTIVE INGREDIENTS: With 4 active ingredients, Orajel Cream provides fast acting and maximum strength relief when you need it most
- KILLS HARMFUL BACTERIA: Unique formula is designed to help kill harmful bacteria in the mouth, and can help to prevent infections
- COOLING RELIEF: To help relieve gum irritation, Orajel 4X cream contains cooling relief
- EASY OPEN: Now with a Ready-Open Tube Tip for easy access to the relief you need. A convenient remedy for use at home or on the go.
$7.48
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−$0.41
Orajel 3X for Toothache & Gum Pain: Maximum Gel Tube 0.42oz - From #1 Oral Pain Relief Brand - Orajel for Instant Pain Relief
- INSTANT PAIN RELIEF: Instant pain relief with Orajel’s maximum strength formula to help relieve pain of the tooth and gums with 20% benzocaine
- KILLS HARMFUL BACTERIA: Unique formula is designed to help kill harmful bacteria in the mouth, and can help to prevent infections
- COOLING RELIEF: To help relieve gum irritation, Orajel toothache gel contains cooling relief
- EASY OPEN: Now with a Ready-Open Tube Tip for easy access to the relief you need. A convenient remedy for use at home or on the go
- From the Oral Pain Reliever Brand for Adults
$6.98
Orajel Maximum Strength Nighttime Toothache Pain Relief Cream - 0.25 Oz
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−$2.00
Organic Clove Essential Oil 30 ml - Pure, Natural, Undiluted for Toothache, Sore Muscles, Skin & Hair Care - Soothing Clove Bud Essential Oil - Nexon Botanics
- 100% Pure & Organic: Nexon Botanics' Organic Clove Essential Oil is undiluted, natural, non-GMO, and cruelty-free. No additives or fillers.
- External Use Only: This natural clove oil is NOT for ingestion. It can be diluted and applied externally to gums or skin, but not meant for internal consumption.
- Tooth & Gum Relief: Apply diluted oil externally on gums or around teeth with a cotton ball to soothe discomfort. Do not swallow.
- Muscle Soothing & Relaxation: Add clove oil organic to massage blends for muscle relaxation and joint comfort.
- Aromatherapy & Skin Care: Enjoy its warm, spicy aroma for relaxation. Dilute for use on itchy skin patches.
$14.95
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−$7.30
Anbesol Maximum Strength Instant Pain Relief Liquid 0.41 oz (Pack of 3)
- Can’t stand your toothache pain one second longer? Choose Anbesol Maximum Strength Liquid to be free from oral pain
- PROVIDES INSTANT, ON CONTACT RELIEF
- PHARMACIST RECOMMENDED
$26.09
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−$3.04
Orajel 4X for Toothache & Gum Pain Severe Gel Tube, No Color, 0.25 Ounce
- Clinical Strength Pain Relief
- Proven to Kill Harmful Bacteria
- Helps Prevent Infection
- Cooling Relief for Gum Irritation
- Now with a Ready-Open Tube Tip for easy access #1 Oral Pain Reliever Brand for Toothache
$6.95
Rite Aid Maximum Strength Liquid Anesthetic Oral Pain Relief - .5 fl oz, Benzocaine 20% | Pain Relief Medications & Treatments | Canker Sore and Tooth Pain Relief for Adults | Mouth Sores Treatment
- MOUTH SORE TREATMENT: Rite Aid Max Strength Oral Liquid Anesthetic Benzocaine 20% pain relieving liquid temporarily relieves pain associated with toothaches, sore gums, mouth sores, canker sores, dentures/braces, cheek bites, and minor dental procedures.
- FAST-ACTING PAIN RELIEF: Rite Aid offers instant relief from pain associated with toothaches, gum pain, canker sores, and dentures/braces. Compare Rite Aid to the leading national brand and get the same reliable mouth pain relief you can count on.
- MAXIMUM STRENGTH: Formulated with 20% Benzocaine, Rite Aid Maximum Strength Liquid Anesthetic Oral Pain Relief offers the maximum amount of pain relief and aims to temporarily relief the mouth and tooth pain that ails you, so you can live pain free.
- ADULTS AND CHILDREN 2 YEARS AND UP: Apply to affected area using applicator tip. Use up to 4 times daily or as directed by a doctor. Children under 12 years of age should be supervised in the use of this product. Children under 2 years of age do not use.
- TRUSTED BRAND SINCE 1962: We hope you continue to choose Rite Aid first for your everyday health and wellness needs. Our mission is to improve the health and wellness of our communities and provide our customers with the best products, services, and advice.
$8.99
SALE
−$1.86
Boiron Hypericum Perforatum 30C Homeopathic Medicine for Relief from Nerve Pain, Toothaches, Pain in Legs or Back, and Shooting Pains - 3 Count (240 Pellets)
- Hypericum provide targeted relief from nerve pain associated with minor injury such as radiating or shooting pain in the back and legs, and toothaches
- Convenient and easy to take meltaway pellets (unflavored)
- Made for adults and children, the pellets melt under the tongue; no food or water needed
- No aspirin, acetaminophen or other NSAIDS and does not contain artificial colors, flavors, sweeteners, or preservatives and there are no known drug interactions
- This over the counter (OTC) homeopathic pack contains 3 easy dispensing tubes for a total of approximately 240 pellets (16 doses per tube; 48 doses per pack) that is portable and easy to dispense tubes: home or travel/on-the-go
$15.60
Orajel 2X Medicated Toothache & Mouth Sores Liquid, 0.45 fl oz
- 20% Benzocaine to relieve oral pain
- Menthol to soothe gums
- Fast-acting liquid for instant pain relief
- #1 Oral Pain Reliever Brand for Toothache
- 2 times as many active ingredients as single medicated oral pain products
$11.29
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API