Pain medicine for toothache can provide much-needed relief when dental discomfort strikes. In 2025, several effective options stand out for their efficacy and accessibility. Over-the-counter medications like ibuprofen and acetaminophen are commonly recommended for their ability to reduce inflammation and alleviate pain. Additionally, topical anesthetics such as benzocaine can offer localized relief. For those seeking natural remedies, clove oil and peppermint tea have been noted for their soothing properties. Prescription options, including stronger analgesics, may be necessary for more severe cases. Always consult with a healthcare professional to determine the best course of action for your specific needs.
DenTek Instant Oral Pain Relief Maximum Strength Kit for Toothaches | 50 Count
- DenTek Instant Pain Relief, Advanced Kit gives instant and precise relief from oral pain and toothaches
- Ergonomic handle to reach any area of the mouth gives simple, no-fingers no-mess, relief
- Fresh Mint flavored Benzocaine relieves tooth pain, sore gums and mouth sores
- Maximum strength pain reliever
- 50 disposable applicators easily slide into the handle for a sanitary way to relieve tooth pain
$9.79
SALE
−$2.51
Orajel 4X for Toothache & Gum Pain: Severe Cream Tube 0.33oz- From Oral Pain Relief Brand
- INSTANT PAIN RELIEF: Instant pain relief with Orajel’s unique 4X clinical strength formula to help relieve pain of the tooth and gums
- 4X ACTIVE INGREDIENTS: With 4 active ingredients, Orajel Cream provides fast acting and maximum strength relief when you need it most
- KILLS HARMFUL BACTERIA: Unique formula is designed to help kill harmful bacteria in the mouth, and can help to prevent infections
- COOLING RELIEF: To help relieve gum irritation, Orajel 4X cream contains cooling relief
- EASY OPEN: Now with a Ready-Open Tube Tip for easy access to the relief you need. A convenient remedy for use at home or on the go.
$7.48
SALE
−$0.41
Orajel 3X for Toothache & Gum Pain: Maximum Gel Tube 0.42oz - From #1 Oral Pain Relief Brand - Orajel for Instant Pain Relief
- INSTANT PAIN RELIEF: Instant pain relief with Orajel’s maximum strength formula to help relieve pain of the tooth and gums with 20% benzocaine
- KILLS HARMFUL BACTERIA: Unique formula is designed to help kill harmful bacteria in the mouth, and can help to prevent infections
- COOLING RELIEF: To help relieve gum irritation, Orajel toothache gel contains cooling relief
- EASY OPEN: Now with a Ready-Open Tube Tip for easy access to the relief you need. A convenient remedy for use at home or on the go
- From the Oral Pain Reliever Brand for Adults
$6.98
SALE
−$1.86
Boiron Hypericum Perforatum 30C Homeopathic Medicine for Relief from Nerve Pain, Toothaches, Pain in Legs or Back, and Shooting Pains - 3 Count (240 Pellets)
- Hypericum provide targeted relief from nerve pain associated with minor injury such as radiating or shooting pain in the back and legs, and toothaches
- Convenient and easy to take meltaway pellets (unflavored)
- Made for adults and children, the pellets melt under the tongue; no food or water needed
- No aspirin, acetaminophen or other NSAIDS and does not contain artificial colors, flavors, sweeteners, or preservatives and there are no known drug interactions
- This over the counter (OTC) homeopathic pack contains 3 easy dispensing tubes for a total of approximately 240 pellets (16 doses per tube; 48 doses per pack) that is portable and easy to dispense tubes: home or travel/on-the-go
$15.60
Red Cross Complete Medication Kit for Tooth Pain, 0.125 oz
- WORKS INSTANTLY
- LONG-LASTING Pain relief
- FORMULATED: Eugenol 85%, an ingredient used by dentists
- KIT INCLUDES: Medication, tweezers, and cotton pellets; Easy, controlled, and accurate application
- USED BY DENTISTS
$9.37
Orajel 2X Medicated Toothache & Mouth Sores Liquid, 0.45 fl oz
- 20% Benzocaine to relieve oral pain
- Menthol to soothe gums
- Fast-acting liquid for instant pain relief
- #1 Oral Pain Reliever Brand for Toothache
- 2 times as many active ingredients as single medicated oral pain products
$11.29
Anadent Toothache Gel, 20% Benzocaine Oral Gel for Instant Pain Relief, Oral and Toothache Medicine for Severe Pain, Fast Acting Relief of Cavity and Canker Sores, 0.25oz
- Benzocaine Oral Gel: The toothache gel contains 20% benzocaine oral gel which is a highly effective active ingredient that gives precise and instant relief for oral discomfort and toothache pain caused by dentures or sores.
- Fast Acting Relief: Using Anadent toothache gel, you'll experience the fast acting relief of toothache pains with the strength of benzocaine. It can also help you to dull the pain long enough for you to fall asleep.
- Toothache Medicine for Severe Pain: This toothache medicine is a cure for almost everything. It promotes the healing of canker sores and can help relieve cavities, tooth pains, sore gums, oral pains, gum pains, and mouth sores.
- Long Lasting: Our maximum strength pain reliever provides immediate pain relief to relieve symptoms of toothache, gum pain, and other dental conditions that last for hours.
- Directions: Apply a small amount of product to the cavity and around the gum surrounding the teeth. Use up to 4 times daily or as directed by a dentist or doctor.
$6.99
BestMade Natural Products Toothache & Nerve Support in Jaw | Helps Ease Tooth Sensitivity and Oral Discomfort Following Dental Work | Bio23 | Pellets
- Natural Relief for Sensitive Teeth: Our homeopathic formula offers gentle, natural support for teeth and nerve sensitivity. It works towards mitigating daily discomforts in your mouth without relying on synthetic chemicals present in over-the-counter remedies.
- Post-Dental Comfort: This remedy is designed to help ease the discomfort often experienced after dental procedures. It's a natural choice that puts your well-being first and can be used as part of your post-dental care routine.
- Responsibly Made: Bestmade Natural Products strives to provide high-quality, all-natural solutions. Our homeopathic remedies are free from harmful additives, prioritizing your health while providing effective relief.
- Trusted Brand Commitment: Bestmade Natural Products is dedicated to providing safe, effective solutions as a trusted brand in the homeopathic industry. Our customer service team is always ready to assist with your questions and concerns.
- Holistic Support: Adding our remedy to your daily routine can contribute to a more holistic, healthy lifestyle. Its natural formulation fits seamlessly into your existing wellness regimen, promoting a more comfortable oral health experience.
$27.99
The Goodbye Company Toothache Pain Relief - Infused with Clove Essential Oil & Peppermint Oil Organic - 100% Natural Tooth Ache Pain Reliever, BPA Free & Made in USA (15ml)
- EXPERIENCE NATURAL PAIN RELIEF: Discover the potent power of our toothache oil, expertly blended with clove bud oil, peppermint oil, and Omega 3 & 9. This natural remedy provides swift and effective relief from dental pain, ensuring you can get back to your day with a smile.
- PURE INGREDIENTS FOR YOUR HEALTH: Our formula is 100% natural and BPA-free, designed with your well-being in mind. We prioritize using only the highest quality ingredients, so you can trust that our oil of cloves for toothache relief is safe and beneficial for you and your family. Try this tooth sensitivity pain relief now!
- SIMPLE & EFFECTIVE USAGE: For precise pain relief, apply a few drops directly to the painful tooth and surrounding gums with a swab. Alternatively, for broader pain and infection control, swish a dropper full in your mouth. Our tooth oil not only alleviates pain but also promotes stronger, healthier teeth, giving you a reason to smile every day.
- THE GOODBYE COMPANY'S MISSION: As a family-owned business, we are passionate about helping people regain hope by effectively addressing common health issues. Our mission is to provide solutions that genuinely improve your quality of life, keeping your family's health at the forefront of everything we do.
- HASSLE-FREE PURCHASE: We are committed to the excellence of our clove oil for tooth aches, and delivering the best customer service possible. Should you encounter any issues with your order or product, please contact us immediately. Your satisfaction is our top priority, and we are here to ensure you have a hassle-free experience.
$17.95
SALE
−$0.51
Rite Aid Severe Toothache and Gum Relief - 0.25 oz
- MOUTH SORE TREATMENT: Rite Aid Severe Toothache & Gum Relief Benzocaine 20% pain relieving gel temporarily relieves pain associated with toothaches, sore gums, mouth sores, canker sores, dentures/braces, cheek bites, and minor dental procedures.
- FAST-ACTING PAIN RELIEF: Rite Aid offers instant relief from pain associated with toothaches, gum pain, canker sores, and dentures/braces. Compare Rite Aid to the leading national brand and get the same reliable mouth pain relief you can count on.
- FOR SEVERE PAIN: Formulated with 20% Benzocaine, Menthol 0.5%, and Zinc Chloride 0.15%, Rite Aid Rite Aid Severe Toothache & Gum Relief offers the maximum amount of pain relief and aims to temporarily relief the mouth and tooth pain that ails you.
- ADULTS AND CHILDREN 2 YEARS AND UP: Apply to affected area using applicator tip. Use up to 4 times daily or as directed by a doctor. Children under 12 years of age should be supervised in the use of this product. Children under 2 years of age do not use.
- TRUSTED BRAND SINCE 1962: We hope you continue to choose Rite Aid first for your everyday health and wellness needs. Our mission is to improve the health and wellness of our communities and provide our customers with the best products, services, and advice.
$5.28
Last update on 2025-05-31 / Affiliate links / Images from Amazon Product Advertising API