OTC for arthritis can provide significant relief for those suffering from joint pain and inflammation. In 2025, several over-the-counter options stand out for their effectiveness and accessibility. These products range from nonsteroidal anti-inflammatory drugs (NSAIDs) to topical treatments that target pain directly at the source. Many users have reported positive results with these remedies, making them a popular choice for managing arthritis symptoms without the need for prescription medications. Whether you're looking for oral pain relievers or creams, the right OTC options can help improve your quality of life.
OTC Premium Support Arthritis Gloves, 1 Pair, Large
- Captures and retains heat to provide therapeutic warmth for fingers and hands. Fits both men and women.
- Soft interior lining wicks away moisture, and keeps hands dry. Open fingertips offer a more comfortable, natural grip with full dexterity.
- Contact closure fastening and adjustment for a custom fit.
- Anatomically shaped to provide even compression for fingers and hands.
- Measure around the hand at the base of the knuckles for sizing. Available Sizes: X-Small (6.5-7 Inches), Small (7-7.75 Inches), Medium (8-8.75 Inches), Large (9-10.5 Inches), and X-Large (10.75-11.5 Inches).
$19.55
SALE
−$2.13
Stopain Pain Relief Roll On Gel 3oz, USA Made, Max Strength Fast Acting with MSM, Glucosamine, Menthol for Arthritis, Lower Back, Knee, Neck, HSA FSA Approved OTC Topical Analgesic Products
- DOES WHAT IT SAYS – Stopain maximum strength products don’t just reduce or dull; our pain relieving Roll-On STOPS your joint, muscle, and arthritis aches and pains fast
- IMMEDIATE PENETRATING RELIEF - Soothing menthol topical analgesic free from dyes, fragrances, and preservatives, works on contact and is non-staining and non-greasy, non-irritating and non-allergenic
- PROVEN TESTED INTEGRITY – Made in the USA for 30+ years with the highest quality ingredients, millions of satisfied customers relieved aching muscles, and joints without intolerable heat or icy cold
- PROFESSIONAL RECOVERY WORKS – Pharmacist and healthcare professional recommended products are easy to use and NSAID free with MSM and Glucosamine to support joint flexibility and mobility
- EXTRA STRENGTH FOR YOUR PAIN – Apply our real time pain reliever for sprains, strains, backache, shoulder, knees, hands, wrist or feet; no need for a patch, liniment, cream, hot balm, ointment or ice
$8.86
Stopain Pain Relief Spray 4oz, USA Made, Max Strength Fast Acting with Menthol, MSM, Glucosamine for Lower Back, Arthritis, Knee, Neck, Joints, HSA FSA Approved OTC Topical Analgesic Product
- DOES WHAT IT SAYS – Stopain maximum strength products don’t just reduce or dull; our pain relieving spray STOPS your joint, muscle, and arthritis aches and pains fast
- IMMEDIATE PENETRATING RELIEF - Soothing menthol topical analgesic free from dyes, fragrances, and preservatives, works on contact and is non-staining and non-greasy, non-irritating and non-allergenic
- PROVEN TESTED INTEGRITY – Made in the USA for 30+ years with the highest quality ingredients, millions of satisfied customers relieved aching muscles, and joints without intolerable heat or icy cold
- PROFESSIONAL RECOVERY WORKS – Pharmacist and healthcare professional recommended products are easy to use and NSAID free with MSM and Glucosamine to support joint flexibility and mobility
- EXTRA STRENGTH FOR YOUR PAIN – Apply our real time pain reliever for sprains, strains, backache, shoulder, knees, hands, wrist or feet; no need for a patch, liniment, cream, hot balm, ointment or ice
$12.99
SALE
−$1.76
Arthritis Hot Pain Relief Creme 3 oz (Pack of 4)
- Quick-acting
- Heating rub
- Long-lasting relief
- For stiffness and sore aching muscles
- NDC: 41167-0600-3 (HUMAN OTC DRUG)
$22.13
OTC Back Warmer Angora Arthritis Relief, White, Large
- Arthritis Relief with lightweight, natural insulation.
- Seven times warmer than wool.
- Helps maintain a steady temperature at the skin surface.
- Breathable, absorbs moisture, comfortable to wear.
- Measure around the waist. Available Sizes: Small (27-30 Inches), Medium (31-35 Inches), Large (36-40 Inches), and X-Large (41-45 Inches).
$36.10
OTC Shoulder Warmer, Angora, Arthritis Relief, X-Large
- Arthritis Relief with lightweight, natural insulation
- Breathable, absorbs moisture, comfortable to wear - Latex free
- 7 times warmer than wool
- Helps maintain a steady temperature at the skin surface
- Measure chest below the pectoral muscle and slightly below the shoulder blade. Available Sizes: Small (30-38 inch / 76-86 cm), Medium (34-38 inch / 86-96.5 cm), Large (38-42 inch / 96.5-107 cm), X-Large (42-46 inch / 107-117 cm)
$24.10
OTC Elbow Warmer Angora Arthritis Relief, White, X-Large
- Arthritis Relief with lightweight, natural insulation.
- Breathable, absorbs moisture, comfortable to wear - Latex free.
- 7 times warmer than wool.
- Helps maintain a steady temperature at the skin surface.
- Measure around the bend of the elbow. Available Sizes: Small (7.75-9.75 Inches), Medium (9.75-11 Inches), Large (11-13.5 Inches), and X-Large (13.5-15 Inches).
$26.90
Saje Pain Release Topical Analgesic Oil Blend, Relieves Pain, Muscle Aches, Backache, Arthritis, Bruises, Strains and Sprains, OTC Roll-On Application, 100% Natural (0.34 fl oz)
- A pain relieving essential oil blend formulated to give you comfort from muscular aches
- Blended with grapeseed oil and 100% natural essential oils: lavender, marjoram, rosemary, cajeput, peppermint, eucalyptus and roman chamomile
- MENTHOL (derived from peppermint): Helps to relieve minor aches and pains of muscles and joints associated with simple backache, arthritis, strains, bruises and sprains
- Apply to affected area up to 3-4 times daily
- Plant-based, vegan and contains no toxins, synthetics, fragrances, parabens or dyes
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OTC Knee Warmer Angora Arthritis Relief, White, Small
- Arthritis Relief with lightweight, natural insulation; Angora warming effects relieve cold, chills, and discomfort from aching.
- Breathable, absorbs moisture, comfortable to wear - Latex free.
- 7 times warmer than wool - Helps maintain a steady temperature at the skin surface.
- Soft, plush material allows for true comfort throughout the day.
- Measure around the bend of the knee. Available Sizes: Small (14.5-16 Inches), Medium (16-18 Inches), Large (18-19.5 Inches), and X-Large (19.5-21 Inches).
$28.72
OTC Wrist-Thumb Splint, Wrap Style Support, Neoprene, Small
- Wrist-thumb splint comfortably supports both wrist and thumb in opposition
- Reversible, can be used on right wrist or left wrist; Measure around the break of the wrist
- Hook and loop fasteners permit easy, one-handed adjustment and application
- Perforated, breathable neoprene interface material allows for comfortable long-term wear
- Holds thumb in opposition; relieves discomfort and prevent reinjury while maintaining full finger dexterity
$12.95
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API