Numbing spray for injections is an essential tool for minimizing discomfort during medical procedures. In 2025, the market offers a variety of effective numbing sprays that cater to different needs, ensuring a more comfortable experience for patients. These sprays are designed to provide rapid relief, making them ideal for both healthcare professionals and individuals seeking at-home solutions. With advancements in formulation and application, the best numbing sprays are now more effective and easier to use than ever before.
DCH Labs 5% Lidocaine Numbing Spray Maximum Strength Relief, 5 oz, Topical Anesthetic That Sprays at Any Angle, Vegan & Cruelty-Free, Secured with Child Resistant Cap
- 5% LIDOCAINE MAXIMUM STRENGTH: The highest strength you can get without a prescription. Delivers fast numbing relief of discomfort, itching, soreness & burning.
- PENETRATES DEEP to block nerve signals. Targets receptors in toes, feet, fingers, hands, back, legs & arms. Ideal for anorectal disorders, anal fissure, also works on tattoo aftercare, minor cuts, scrapes, burns, bites, muscle & joints.
- SPRAYS AT ANY ANGLE: Our continuous spray can is ideal for all the hard-to-reach areas. Touchless, mess-free application allows you to spray at any angle, even when upside down.
- ODOR FREE & NON-GREASY infused with Aloe Vera, Vitamin E, Cucumber & Chamomile. Vegan & Cruelty-Free with no parabens or silicones.
- MADE IN USA: Valued sized 5 OUNCE CAN is secured with a Child-Resistant Cap
$19.99
Medique MP230-17 Medi-First Cold Spray, 4 oz, Capacity, Volume, Standard, 4 O, White/Blue
- Topical cooling spray
- Instantly cools skin
- Reduces swelling and pain
- 4oz. spray can
$9.84
NUMSTAT Antiseptic Numbing Wipes for Needle Pain Relief, 2-In-1 Formula with Benzocaine, Isopropyl Alcohol and Menthol - 30 Prep Pads
- Relieves Needle Pain - You can now prepare for needle pain with NUMSTAT. If applied in advance to the area, NUMSTAT’s proprietary blend will be there to relieve the pain with 15% Benzocaine and 1% Menthol, while it cleans and kills germs reducing the risk of infection with 71% Isopropyl Alcohol. Perfect for finger sticks!
- Fast Acting Antiseptic Prep Wipe for Needle Sticks - Applied in advance to the injection site, NUMSTAT’s prep pad cleans, kills germs, and relieves the pain of needle sticks with fast-acting Benzocaine. Simply apply the pad solution to the skin, gently rub into the skin for 60 seconds* and let dry. NUMSTAT helps reduce the pain of needle sticks. Test the injection site for effect by touching the area before performing the procedure. May need to reapply on certain skin types.
- Convenient, Single-Use Prep Pad - NUMSTAT is supplied in convenient individual foil pouches that you can just tear open. The NUMSTAT solution on the non-woven prep pad works fast to prepare the site. It is durable yet soft and non-abrasive to your skin. NUMSTAT can go anywhere and fits in your pocket, purse, travel bag or first-aid kit.
- Developed by Doctors - Many people are afraid of needles and the pain they bring. Intense fear of needle sticks can cause people to delay or avoid necessary medical care such as diabetic testing. NUMSTAT was developed by doctors to help people with the fear and pain of needle sticks. Applied in advance, NUMSTAT relieves needle pain.
- How to Use - For adults and children 2 years of age and older, apply to the affected site no more than 4 times daily. Simply apply the pad solution to the skin and gently rub in* and let dry. Use a glove on the application hand or always wash application hand immediately after application. For full directions for use and warnings, please refer to the Drug Facts Label located on the NUMSTAT box.
$7.97
SALE
−$3.24
Bactine MAX First Aid Spray - Pain Relief Cleansing Spray with 4% Lidocaine - Numbing Lidocaine Kills 99.9% of Germs - Pain + Itch Relief For Minor Cuts & Scrapes, Burns & Bug Bites - 5oz
- Bactine Max Pain Relieving Antiseptic Spray with Lidocaine, First Aid Pain + Itch Relief, No-Sting, Kills 99% of Germs*, 5oz
- Pain Relief + Skin Infection Protection --- Get a better value than tiny tubes of ointment. Bactine Max Pain Relieving Spray is an antiseptic minor wound, burn, and bug bite cleanser that provides immediate pain relief + itch relief. All while protecting against infection.
- Kills 99% of Germs --- Feel confident knowing you are protected. Bactine Max uses benzalkonium chloride and effectively kills 99% of germs associated with skin infections. It stops the growth of bacterial microorganisms on the skin to prevent infection of wounds, burns, and insect bites.
- Max Strength Pain Relief --- Boo-boos hurt enough. Why add to that? Formulated with 4% Lidocaine, a topical analgesic, that numbs the pain. It interferes with the transmission of nerve pain signals from the site of application. It has the maximum lidocaine amount allowed by the FDA for OTC products for local anesthetics.
- No-Sting Means No Worries --- Treat your family with a tear free first aid wound care. Unlike other hydrogen peroxide or alcohol based wound care products, Bactine cleanses and protects without a painful, harsh sting. It provides temporary relief of pain and itching from minor wounds, bug bites, and burns. It won't leave a brown stain on skin like iodine-based products.
$4.75
SALE
−$2.40
Aspercreme Lidocaine Dry Spray Soothes Aggravated Nerves, Numbing Topical Pain Relief Spray with Max-Strength 4% Lidocaine Sprays at Any Angle, 4 Oz.
- Contains one (1) 4-oz. spray bottle of Aspercreme Lidocaine Pain Relief Dry Spray, designed to numb away nerve pain
- Fast-Acting Relief: Max-strength 4% lidocaine pain relief dry spray targets nerves and numbs away pain
- Fragrance-Free Formula: Aspercreme pain relief dry spray has no odor for discreet pain relief
- Maximum-Strength Lidocaine: OTC Aspercreme offers the maximum-strength lidocaine pain relief available without a prescription and is FSA/HSA eligible
- Keeps Hands Clean: Non-greasy Aspercreme pain relief spray dries quickly and works at any angle
$9.59
Bravado Labs Numbing Spray - Anesthetic Numb Formula - Extra Strength Pain Relief for Tattoos, Microblading, Waxing - 1 oz
- NUMB IT UP: Whether you’re about to go under the tattoo gun, wax some body/facial hair, or get a piercing, this 5% pain ease numbing spray for waxing can make the process a whole lot less painful. Rushing relief in just 5-15 minutes which lasts up to an hour, this topical anesthetic can spare you from a painful ordeal.
- DITCH THE ITCH: You can also use this pain relief numbing spray for injections to treat common skin conditions that cause pain, itching or discomfort such as minor burns, insect bites, eczema, scratches and even hemorrhoids and erectile disorders.
- QUICK RELIEF: At Bravado Labs, we know that when you really need relief, you don’t want to wait half an hour for it to take effect. That’s why we created our formula to start working in as little as five minutes. Within 20 minutes, this tattoo/waxing numbing spray for piercing will have reached peak effectiveness at both numbing and soothing pain and itchiness.
- MAXIMUM STRENGTH: With 5% formula, we made our piercing numbing spray as strong as we could without requiring a prescription. The result is blissful though temporary relief from conditions that would otherwise cause discomfort on the surface of your skin. Wearing off? You can apply it up to six times daily.
- SOOTHING DELIGHT: If you’re not happy with the effectiveness of Bravado Labs Numb Spray Pain Relief, just let us know and we’ll make it right. Say goodbye to suffering from a painful piercing, waxing, tattoo, burn, bug bite or other skin condition, and say aaaaah with the quick numbing action of Lidocaine Spray Maximum Strength from Bravado Labs!
$17.99
Deep Numbing Cream for Piercing, Injections& Tattoos, Fast Numbing for Waxing, 7 Hours Maximum Strength Numbing Cream for Injections, 8x Numbing with Emu Oil and Arnica. 30ml/1floz
- DEEP NUMBNESS: Nupharmisto deep numbing cream provide soothe itching, soreness, and burning of piercing, injections, waxing, and micro-needling. allows you to feel more comfortable during your procedure.
- EFFECTIVE HEALING PROPERTIES: Our numbing cream contains a blend of powerful healing ingredients, including Arnica, and Emu Oil, to help speed up the healing process. It helping to heal, soothe and moisturize your skin. This means less scabbing, resulting in a beautiful, vibrant result.
- FAST & EASY TO USE: This numbing cream starts to work in 20 minutes, 45 minutes can start your process, but if left on for 50 minutes it will peak.（keeping it on longer gives better effects） We recommend patch testing before use to ensure compatibility with your skin.
- MULTIPURPOSE: It can be used for a variety of procedures, including tattooing, piercing, microblading, micro needling, laser hair removal, and waxing. This means you can enjoy the benefits of our cream for all your cosmetic and beauty needs.
- ODOR-FREE, OIL-FREE & NON-GREASY: Our numbing cream is easy to apply and remove, leaving no mess behind. It's contains no harsh chemicals, making it safe for all skin types.
$22.90
Gebauer's Instant Ice: Topical Skin Refrigerant and Cold Spray
- Instant Topical Skin Refrigerant
- Works immediately so there is no wait time
- Safe, effective cold spray that can be reapplied as necessary
- Can be applied through clothing
- Compact and fits easily into gym bag
$25.65
Ebanel 5% Lidocaine Spray Pain Relief Numb520 Burn Itch Relief Numbing Spray for Skin, Topical Anesthetic Postpartum Hemorrhoid Treatment with Phenylephrine for Local and Anorectal Uses
- FSA HSA Eligible OTC Medications & Treatments - This topical lidocaine numb spray enhanced with 0.25% Phenylephrine HCl and Allantoin, temporarily relieves pain, burning, itching, and discomfort, reduces swelling, inflammation, soreness, and protects irritated skin in local and anorectal areas
- 5% Lidocaine Spray Maximum Strength - This pain relief anti itch spray provides immediate relief for minor aches, minor cuts, minor scrapes, minor burns, sunburn, scrapes, and minor skin irritations. It also works for mosquito bite itch relief, bug bite itch relief, insect bite relief, postpartum relief, hemorrhoid shrinking treatment, and anorectal disorders
- Enhanced Liposomal Deep Penetrating Pain Relief Spray - Best efficacy, fast-acting & long-lasting. It begins numbing in 2-3 minutes, peaks after 5-10 minutes, and lasts for 1 hour from its peak. Numbing performance may vary depending on the thickness of skin area, and individual metabolism
- Oil-Free, Odor-Free & Non-Greasy - Hypoallergenic, no harsh chemicals, non-addictive. Apply during and after treatment, may reapply halfway for enhanced effect. Water-based formula for easy, hands-free application. No need to remove it after
- Made in USA in an FDA Registered Facility - Cruelty-Free, cGMP Certified, secured with a child-resistant cap. A performance test before treatment is highly recommended to assess your best performance timing
$19.99
Myderm Medical Numbing Spray - 4.5oz - Maximum Strength 5% Lidocaine with Phenylephrine HCl and Witch Hazel - Fast-Acting Reliever with A Touch-Free Application - First Aid Supplies - Made in USA
- Get Ahead of discomfort: Experience faster relief, piercing and tattoo numbing, and relief from foot discomfort with myDerm MEDICAL Numbing Spray. Our numbing spray is formulated with 5% Lidocaine, Phenylephrine HCl, and Witch Hazel - ingredients that work together to help temporarily numb and relieve ache from minor burns, skin abrasions, itchy skin, and anorectal conditions.
- Fast Acting, Touch-Free Application: Our topical lidocaine works fast and penetrates deep into the skin to help soothe swelling and burning. Our rapid topical discomfort sprays at any angle with a touch-free application for hygienic purposes. Great for numbing, piercing and tattoo aftercare, as well as muscle discomfort.
- Paraben Free: It can be difficult to find numbing products that don't contain parabens and fillers, but our formula has been and will always be free from parabens. That means it is safe and formulated not to irritate your skin or cause dryness and discomfort after use.
- Made in the USA: We manufacture in a licensed and regulated facility in the United States. You can rest assured that our products are safe for you and your family.
- Innovative Formulas, Affordable Solutions: Our innovative products range from ache ease, first aid, skin care, to anti-aging products. No matter what you're looking for, we want you always to find comfort in myDerm.
$17.99
Last update on 2025-05-03 / Affiliate links / Images from Amazon Product Advertising API