Nose spray for congestion is an essential remedy for those seeking quick relief from nasal blockages and discomfort. In 2025, the market offers a variety of effective options that cater to different needs, including saline sprays, decongestants, and natural formulations. These sprays not only help clear nasal passages but also provide soothing relief from irritation. Whether you're dealing with seasonal allergies or a common cold, finding the right nose spray can significantly improve your breathing and overall comfort.
Afrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)
- Ridiculously Fast Relief: Unblock your nose in seconds with Afrin No Drip Severe Congestion Nasal Mist, a fast-acting nasal pump mist decongestant providing sinus pressure and congestion relief with cooling menthol in a convenient twin pack
- Effective for Severe Congestion: This maximum strength nasal spray is perfect for relieving severe nasal congestion and sinus pressure caused by colds and allergies, offering quick and effective stuffy nose relief for adults and children 6 years and older
- No Drip Technology: Afrin's No Drip technology ensures the medicated mist stays where it's sprayed, providing effective nasal decongestion without the mess or discomfort of it dripping from your nose or down your throat
- Cooling Menthol Formula: Experience the soothing and cooling sensation of menthol while the powerful decongestant works to constrict blood vessels in the nasal passages and reduce swelling to help you breathe easier
- 12-Hour Non-Drowsy Decongestion: Experience long-lasting relief for up to 12 hours without drowsiness, perfect for both day and night use to alleviate nasal congestion and provide sinus pressure relief
$16.49
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−$2.52
Vicks Sinex SEVERE Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Stuffy Nose due to Cold or Allergy, & Nasal Congestion, Sinus Pressure Relief, 265 Sprays x 2
- Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses
- Breathe better all day or all night long with Vicks Sinex Severe. For instant, 12-hour, nasal congestion and sinus pressure relief
- This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell, Not intended for daily use
- Unlike nasal decongestant tablets, Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes
- Vicks Sinex Severe Nasal Spray is HSA and FSA eligible, Check with your provider for more details
$14.97
Amazon Basic Care No Drip Severe Congestion Nasal Pump Mist Spray, 12 Hour Relief, Oxymetazoline HCl, Maximum Strength Plus Menthol, Steroid Free, 1 fl oz (Pack of 1)
- ACTIVE INGREDIENT: This nasal spray contains oxymetazoline HCl, a nasal decongestant and the doctor recommended adult nasal spray active ingredient (source: IQVIA physicians survey 2019), which compares to the active ingredient in Afrin No Drip. Offers maximum strength nasal congestion relief.
- 12 HOUR, MAXIMUM STRENGTH RELIEF: Amazon Basic Care Severe Congestion Nasal Spray, Oxymetazoline HCl provides 12 hours of maximum strength nasal congestion relief due to the common cold, hay fever and upper respiratory allergies.
- FAST NASAL CONGESTION RELIEF: Amazon Basic Care Severe Congestion Nasal Spray, Oxymetazoline HCl provides fast and powerful relief for colds and allergies. Temporarily relieves sinus congestion and pressure.
- NASAL RELIEF: Amazon Basic Care Severe Congestion Nasal Spray, Oxymetazoline HCl provides temporary nasal congestion relief by shrinking swollen nasal membranes so you can breathe more freely.
- NO DRIP NASAL SPRAY: This cold and allergy relief nasal spray won't drip down your nose or throat. Severe congestion formula pump mist. Safety Sealed. This product is gluten free. Contains Menthol.
$4.89
Beekeeper's Naturals Nasal Spray for Adults with Propolis, Xylitol & Saline, Clears Nasal Congestion, Moisturizes Sinus Canal, & Decongest Sinus Cavities, 1 fl oz
- NASAL SPRAY DECONGESTANT FOR SINUS RELIEF ---- Our effective nasal spray will rinse clean and moisturize the nasal canal tissues. It will help reduce symptoms caused by irritants such as bacteria, pollen, pollution etc. It also acts as a decongestant by focusing primarily on the root cause of congestion
- NATURAL INGREDIENTS ---- Saline solution specially formulated from natural sea salt and purified water, combined with a potent dose of propolis and xylitol that contains powerful oral and upper respiratory health benefits and yet a gentle relief and treatment for sinus swelling and congestion caused by irritants seasonal pressure, dust, sinusitis, rhinitis, etc.
- SAFE RINSE & SPRAY FOR NASAL PASSAGE ---- Our natural sinus cleaner is kids friendly, uses non-GMO and non-addictive ingredients and is proven effective against itchy, irritated nasal passage without the use of dangerous chemicals such as steroids and drugs. It acts as a natural solution that expands airways and reduces swelling
- HOW TO USE NASAL SPRAY EFFECTIVELY ---- Shake well before squeezing twice in each nostril as needed and the spray blows gently into your nose to clear congestion such as mucus. Each spray helps clear nasal congestion while gently soothing and moisturizing the nasal passages
- SUSTAINABLY SOURCED ---- We practice sustainable beekeeping and make the happiness of our bees a priority. Our bee products are sourced from remote apiaries and are among the purest on earth
$13.99
Afrin No Drip Extra Moisturizing 12 Hour Nasal Congestion Relief Pump Mist, Sinus Spray Decongestant - 15 mL
- Afrin No Drip Extra Moisturizing is a nasal pump mist designed to relieve nasal congestion for up to 12 hours
- Nasal decongestant pump mist works instantly to provide nasal and sinus congestion relief caused by allergies or other nasal irritants.
- Medicated no drip nasal spray doesn’t drip from your nose or down your throat
- 12 hour medicated moisturizing nasal spray soothes dry nasal passages
- Use Afrin nasal mist as directed, spraying two or three times into each nostril for no more than three days
$9.46
Vicks Sinex Severe Nasal Spray, Moisturizing Ultra Fine Mist with Aloe, Decongestant Medicine, Relief from Stuffy Nose Due to Cold or Allergy, Nasal Congestion & Sinus Pressure Relief, 265 Sprays x 2
- INSTANT SINUS RELIEF: Vicks Sinex Severe Nasal Spray clears your stuffy nose in seconds and works 6x faster vs. nasal decongestant tablets.
- LAST 12 HOURS: Breathe freely with powerful sinus and congestion relief day or night
- WORKS AT THE SOURCE: Targets nasal congestion at the source to help you breathe easier
- POWERFUL VICKS VAPORS: Vicks vapors provide soothing and comforting relief of your congestion
- MOISTURIZING: Contains hints of aloe
$17.49
Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays
- Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses
- Breathe better all day or all night long with Vicks Sinex Severe. For instant, 12-hour, nasal congestion and sinus pressure relief
- This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell, Not intended for daily use
- Unlike nasal decongestant tablets, Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes
- Vicks Sinex Severe Nasal Spray is HSA and FSA eligible, Check with your provider for more details
$10.46
ARM & HAMMER Simply Saline Nasal Care Daily Mist 4.5oz – Instant Relief for Every Day Congestion – One 4.5oz Bottle
- ARM & HAMMER Simply Saline Daily Care Nasal Mist 4.5 oz (127 g) saline nasal spray provides instant relief for everyday nasal congestion while gently cleansing and moisturizing dry noses
- This fast-acting saline nose spray helps naturally moisturize dry nasal passages and and clear congestion associated with year-round allergies or colds; it gently flushes out mucus, dust, pollen, and other irritants to help you breathe easier
- Safe for pregnant women and adults, this drug-free nasal spray is free of fragrances, dyes, artificial flavors, and parabens; it’s made with 3 simple, pure ingredients: purified water, salt, and real ARM & HAMMER Baking Soda
- This saline nasal spray provides instant congestion relief to help you breathe easy and keeps nasal passages well-moisturized to help prevent dry nosebleeds; also helps relieve blocked nasal passages to promote better sleep and sports activity
- This drug-free nasal spray saline solution delivers a comforting mist that contains no steroids; its isotonic formula safely soothes and helps clear nasal passages without causing any drowsiness or side effects
$8.54
Flonase Allergy Relief Nasal Spray, 24-Hour Non-Drowsy Multi-Symptom Relief – 144 Sprays, Bonus Pack of Tissues
- One 144-spray bottle of Flonase Allergy Relief Nasal Spray, 24-hour non-drowsy allergy medicine, metered nasal spray plus Bonus Pack of Tissues
- Flonase Allergy Relief Nasal Spray is a 24-hour non-drowsy allergy medicine that blocks 6 allergic substances to stop your body from overreacting to allergens
- Containing fluticasone propionate, the most prescribed allergy medication (2), Flonase relieves nasal congestion plus runny nose, sneezing, itchy nose, and itchy, watery eyes (1)
- Number 1 doctor recommended allergy brand delivers long-lasting full prescription strength relief from allergies
- Works year-round to relieve indoor and outdoor allergy symptoms caused by allergens including pollen, mold, dust mites and pet dander
$27.99
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API