10 Best nighttime cold medicine (2025)

• ACTIVE INGREDIENTS: This product contains acetaminophen (pain reliever and fever reducer), dextromethorphan HBr (cough suppressant) and doxylamine succinate (antihistamine) which compares to the active ingredients in Vicks NyQuil Cold & Flu.
• POWERFUL NIGHTTIME RELIEF: This cold and flu medicine provides multi-symptom relief of common cold and flu symptoms while you sleep.
• PAIN RELIEVER AND FEVER REDUCER: Relieves sore throat, minor aches and pains and reduces fever associated with the common cold and flu.
• COUGH SUPPRESSANT: This nighttime cold and flu relief medicine helps to relieve coughing so you can rest.
• ANTIHISTAMINE: Helps relieve runny nose and sneezing associated with the common cold and flu.

• ACTIVE INGREDIENTS: Active ingredients are Acetaminophen 650 mg, Dextromethorphan HBr 30 mg, and Doxylamine succinate, 12.5 mg. Compare to the active ingredients of Vicks NyQuil Cold & Flu
• RELIEVES COLD & FLU SYMPTOMS: Amazon Basic Care Nighttime Cold & Flu Relief provides multi-symptom relief by helping with common symptoms such as aches, fever, cough, sneezing and runny nose
• NIGHTTIME COLD AND FLU RELIEF: Amazon Basic Care Nighttime Cold and Flu Relief relieves cold and flu symptoms so you can rest through the night.
• EFFECTIVE: Acts as a pain reliever, fever reducer, cough suppressant and antihistamine.
• GLUTEN FREE: This product is Gluten Free. Contains 10% ALCOHOL.

• ACTIVE INGREDIENTS: This product contains a pain reliever/fever reducer, cough suppressant, antihistamine and nasal decongestant. Compare to the active ingredients in Vicks NyQuil Severe+ VapoCOOL
• EFFECTIVE: Temporarily relieves common cold and flu symptoms such as nasal congestion, sinus congestion and pressure, runny nose and sneezing, minor aches and pain, sore throat and cough
• COATED CAPLETS provide maximum strength, common cold and flu symptom relief
• NIGHTTIME COLD and FLU RELIEF for minor aches and pains, fever, nasal congestion, sinus pressure, sneezing, runny nose and cough
• VAPOR ICE: Soothing Vapor Ice flavor in gluten free cold and flu symptom medicine

• ✅ POWERFUL MULTI-SYMPTOM RELIEF: Temporarily relieves common cold & flu symptoms including nasal congestion, cough due to minor throat and bronchial irritation, sore throat, headache, fever and minor aches & pains.
• ✅ Fast-Acting: Puregen Labs formula allows for quick and easy absorption, providing fast-acting relief when you need it most. Say goodbye to the discomfort of cold and flu symptoms and let your body recover during restful sleep.
• ✅ Power of One: Puregen Labs NightTime relief single softgel liqui capsule contains pain reliever, fever reducer, cough suppressor and antihistamine to make sure nothing is bothering you during your sleep.
• ✅ Value Pack Savings: Our maximum strength Nighttime Relief contains same active ingredient as name brand product but for a fraction of the cost.

• ACTIVE INGREDIENTS: Compare to the active ingredients in Vicks NyQuil Severe Cold and Flu, acetaminophen 650 mg, dextromethorphan HBr 20 mg, doxylamine succinate 12.5 mg and phenylephrine HCl 10 mg
• MAXIMUM STRENGTH RELIEF: Each dose includes a pain reliever/fever reducer, cough suppressant, antihistamine and nasal decongestant so you can rest; this medicine also contains ten percent alcohol
• FOR NIGHT TIME USE: Amazon Basic Care Night Time Severe Cold and Flu Relief soothes your severe symptoms to help you sleep
• MULTI-SYMPTOM RELIEF: Temporarily relieves common cold and flu symptoms: fever, minor aches and pains, sore throat, coughing, sneezing, runny nose and sinus pressure
• SOOTHES COLD AND FLU SYMPTOMS: Promotes nasal and/or sinus drainage and temporarily restores freer breathing through the nose; this medicine is sugar free and gluten free; for ages 12 and older

• ACTIVE INGREDIENTS: Compare to the active ingredients of NyQuil Cold and Flu: acetaminophen (pain reliever and fever reducer), dextromethorphan HBr (cough suppressant), and doxylamine succinate (antihistamine)
• POWERFUL NIGHTTIME RELIEF: Each dose relieves minor aches and pains, fever, sore throat, sneezing, runny nose and cough for up to 6 hours
• MAXIMUM STRENGTH: This flu and cold medicine provides maximum strength, multi-symptom relief to help you sleep
• COUGH SYRUP: The cough suppressant calms your nighttime coughing so you can rest; contains 10% alcohol
• AGES 12 AND OLDER: This cherry flavor cold and flu medicine is safe for adults and children ages 12 and over; gluten free

This HealthA2Z® Nighttime | Cold & Flu Medicine | Powerful Multi-Symptom Daytime and Nighttime Relief (20 Softgels) (20 Softgels) is a top choice in . Customers appreciate its quality, performance, and value.

• POWERFUL MULTI-SYMPTOM RELIEF for your headache, fever, sore throat, minor aches and pains, sneezing, runny nose, and cough.
• EFFECTIVE NIGHTTIME COLD & FLU SYMPTOM RELIEF. NyQuil Cold & Flu Liquicaps temporarily relieves common cold & flu symptoms so you can get the rest you need
• FAST RELIEF SO YOU CAN SLEEP. Don't let your cold keep you up. Just one dose of NyQuil starts working fast to provide effective cold & flu relief
• POWER THROUGH YOUR WORST COLD & FLU SYMPTOMS. Life doesn’t stop when you have a cold. NyQuil relieves bothersome symptoms such as cough and fever so that you can get the rest you need
• WORLD'S #1 SELLING OTC COUGH AND COLD BRAND. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms.