Nasal spray for sinusitis can provide significant relief for those suffering from this common condition. In 2025, the market offers a variety of effective options designed to alleviate symptoms such as congestion, pressure, and inflammation. These sprays often contain ingredients like saline, corticosteroids, or antihistamines, which work to reduce swelling and promote drainage. Choosing the right nasal spray can make a substantial difference in managing sinusitis, ensuring you breathe easier and feel more comfortable.
SALE
−$2.52
Vicks Sinex SEVERE Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Stuffy Nose due to Cold or Allergy, & Nasal Congestion, Sinus Pressure Relief, 265 Sprays x 2
- Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses
- Breathe better all day or all night long with Vicks Sinex Severe. For instant, 12-hour, nasal congestion and sinus pressure relief
- This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell, Not intended for daily use
- Unlike nasal decongestant tablets, Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes
- Vicks Sinex Severe Nasal Spray is HSA and FSA eligible, Check with your provider for more details
$14.97
Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays
- Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses
- Breathe better all day or all night long with Vicks Sinex Severe. For instant, 12-hour, nasal congestion and sinus pressure relief
- This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell, Not intended for daily use
- Unlike nasal decongestant tablets, Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes
- Vicks Sinex Severe Nasal Spray is HSA and FSA eligible, Check with your provider for more details
$10.46
SALE
−$1.76
Mucinex Sinus-Max Oxymetazoline Nasal Spray Decongestant,12 Hour Over-The-Counter Medication Nose Spray for Sinus Relief, Nasal Decongestants For Adults, Allergy Congestion Relief, 0.75 Fl Oz
- MUCINEX OVER-THE-COUNTER NASAL SPRAY: Mucinex Sinus-Max Severe Nasal Congestion Relief helps relieve nasal congestion, sinus congestion, and sinus pressure
- NASAL SPRAY DECONGESTANT: A blast of Oxymetazoline HCI, a powerful topical nasal decongestant, that starts working immediately and provides nasal congestion relief for up to 12 hours
- NOSE SPRAY SINUS MEDICINE FOR SINUS RELIEF: Mucinex Sinus Max nasal spray applies a targeted nasal mist directly to your nasal passages to help clear sinus congestion fast
- NASAL DECONGESTANTS FOR ADULTS: Use as directed, for adults and children ages 6+ (with adult supervision)
- SINUS & ALLERGY SYMPTOM RELIEF: Powerful relief from nasal and sinus congestion due to common cold, hay fever, other respiratory allergies
$8.23
HealthA2Z Fluticasone Propionate Nasal Sprays, 24 Hour Allergy Relief,120 Sprays, 0.54 fl oz
- 24-HOUR ALLERGY RELIEF: HealthA2Z Fluticasone Propionate Nasal Spray temporarily relieves symptoms of hay fever or other upper respiratory allergies: Itchy, Watery Eyes, Nasal Congestion, Runny Nose, Itchy Nose, Sneezing.
- NON-DROWSY: A non-drowsy nasal spray that allows you to go about your day with all day relief from common allergy symptoms.
- WARNINGS: only for use in the nose. Do not spray into your eyes or mouth.
- DIRECTIONS: Week 1: use 2 sprays in each nostril daily/Week 2 through 6 months: use 1 or 2 sprays in each nostril once daily, as needed to treat symptoms/After 6 months of daily use: ask a doctor if you can keep using.
$14.45
Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)
- ACTIVE INGREDIENT: This nasal spray contains oxymetazoline hydrochloride 0.05%, a nasal decongestant. Compare to the active ingredient in Afrin Original.
- PURPOSE: This nasal spray temporarily relieves nasal congestion, sinus congestion and pressure due to the common cold, hay fever and upper respiratory allergies.
- 12 HOUR RELIEF: Amazon Basic Care Maximum Strength Nasal Spray provides fast, powerful congestion relief for allergies and colds for up to 12 hours.
- FAST CONGESTION RELIEF: Provides fast and powerful nasal congestion relief for allergies and colds.
- FAST-ACTING NASAL DECONGESTANT clears stuffy nose due to upper respiratory allergies and the common cold.
$6.71
Beekeeper's Naturals Nasal Spray for Adults with Propolis, Xylitol & Saline, Clears Nasal Congestion, Moisturizes Sinus Canal, & Decongest Sinus Cavities, 1 fl oz
- NASAL SPRAY DECONGESTANT FOR SINUS RELIEF ---- Our effective nasal spray will rinse clean and moisturize the nasal canal tissues. It will help reduce symptoms caused by irritants such as bacteria, pollen, pollution etc. It also acts as a decongestant by focusing primarily on the root cause of congestion
- NATURAL INGREDIENTS ---- Saline solution specially formulated from natural sea salt and purified water, combined with a potent dose of propolis and xylitol that contains powerful oral and upper respiratory health benefits and yet a gentle relief and treatment for sinus swelling and congestion caused by irritants seasonal pressure, dust, sinusitis, rhinitis, etc.
- SAFE RINSE & SPRAY FOR NASAL PASSAGE ---- Our natural sinus cleaner is kids friendly, uses non-GMO and non-addictive ingredients and is proven effective against itchy, irritated nasal passage without the use of dangerous chemicals such as steroids and drugs. It acts as a natural solution that expands airways and reduces swelling
- HOW TO USE NASAL SPRAY EFFECTIVELY ---- Shake well before squeezing twice in each nostril as needed and the spray blows gently into your nose to clear congestion such as mucus. Each spray helps clear nasal congestion while gently soothing and moisturizing the nasal passages
- SUSTAINABLY SOURCED ---- We practice sustainable beekeeping and make the happiness of our bees a priority. Our bee products are sourced from remote apiaries and are among the purest on earth
$13.99
SALE
−$0.70
Xlear Nasal Spray with Xylitol, 1.5 fl oz (Pack of 1)
- NATURAL SALINE SOLUTION & NASAL RINSE: Our nasal saline spray will gently clean and moisturize the sinus tissues. Unlike other normal saline nasal sprays our spray can also decongest the sinuses by targeting the primary causes of nasal congestion. Our nose spray will help reduce tissue swelling from pollen, pollution, contaminants, and other irritants.
- SAFE NASAL RINSE & SPRAY: Our all-natural nasal cleaner is safe for kids, non-addictive, Non-GMO Project Verified and is effective without the use of steroids, drugs, or chemicals. It is the ideal daily sinus medicine that will reduce swelling and open your airways. Using our saline nose spray before bed may reduce snoring.
- IMPROVED FORMULA WITH XYLITOL: Our patented saline nasal spray solution may reduce tissue inflammation and naturally open airways. Xylitol's powerful oral and upper respiratory health benefits come from its unique five-carbon structure. Xylitol may help reduce swelling and allergy symptoms by reducing contaminant adhesion on your nasal tissue.
- EASY TO USE DIRECTIONS: Clear the nasal passageway by gently blowing your nose before using Xlear. Prime the pump by holding the sinus rinse bottle upright and pumping one or more times until the saline solution is dispensed. Insert nozzle into nostril and depress pump completely while breathing in through your nose. Spray each nostril 2-4 times and use at least twice daily.
- WASH AWAY POLLUTANTS: Our natural saline nasal spray can wash away pollutants and help to bring sinus relief. Use our sinus spray daily to protect and keep your nasal passages clean. Each 1.5 oz bottle delivers approx. 240 fine mist Sprays so you can find fast and quick relief.
$11.79
Flonase Allergy Relief Nasal Spray, 24-Hour Non-Drowsy Multi-Symptom Relief - 72 Sprays plus Bonus Pack of Tissues
- One 72-spray bottle of Flonase Allergy Relief Nasal Spray, 24-hour non-drowsy allergy medicine, metered nasal spray plus Bonus Pack of Tissues
- Flonase Allergy Relief Nasal Spray is a 24-hour non-drowsy allergy medicine that blocks 6 allergic substances to stop your body from overreacting to allergens
- Containing fluticasone propionate, the most prescribed allergy medication (2), Flonase relieves nasal congestion plus runny nose, sneezing, itchy nose, and itchy, watery eyes (1)
- Number 1 doctor recommended allergy brand delivers long-lasting full prescription strength relief from allergies
- Works year-round to relieve indoor and outdoor allergy symptoms caused by allergens including pollen, mold, dust mites and pet dander
$17.49
Seagate Products Homeopathic Olive Leaf Nasal Spray (Pack of 1) 1 Ounce
- Olive Leaf Nasal Spray, 1 oz - 1-Pack
- Safe, fast, and effective for the temporary relief of sinus irritations
- Homeopathic; Safe for Children; Chemical free; Pure natural ingredients
- Non-habit forming; Does not have the side-effects of modern pharmaceutical drugs
$13.91
Last update on 2025-05-01 / Affiliate links / Images from Amazon Product Advertising API