Nasal spray for sinus infection can provide significant relief for those suffering from sinusitis, helping to reduce inflammation and clear nasal passages. In 2025, several products stand out for their effectiveness and user satisfaction. These sprays often contain ingredients like saline, corticosteroids, or antihistamines, which work together to alleviate symptoms and promote healing. When choosing a nasal spray, it's essential to consider factors such as the severity of your symptoms, any underlying conditions, and potential side effects. With the right nasal spray, you can find the relief you need to breathe easier and feel better.
SALE
−$2.52
Vicks Sinex SEVERE Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Nasal Congestion due to Cold or Allergy, Sinus Pressure Relief, 265 Sprays x 2
- Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses
- Breathe better all day or all night long with Vicks Sinex Severe. For instant, 12-hour, nasal congestion and sinus pressure relief
- This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell, Not intended for daily use
- Unlike nasal decongestant tablets, Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes
- Vicks Sinex Severe Nasal Spray is HSA and FSA eligible, Check with your provider for more details
$14.97
Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays
- Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses
- Breathe better all day or all night long with Vicks Sinex Severe. For instant, 12-hour, nasal congestion and sinus pressure relief
- This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell, Not intended for daily use
- Unlike nasal decongestant tablets, Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes
- Vicks Sinex Severe Nasal Spray is HSA and FSA eligible, Check with your provider for more details
$9.96
Beekeeper's Naturals Propolis Nasal Rinse Spray Max, Relief for Adults w/Eucalyptus, Oregano & Saline, Clears Nasal Congestion, Moisturizes Sinus Canal, & Decongest Sinus Cavities, 1 fl oz
- POTENT HERBAL NASAL SPRAY DECONGESTANT TO INVIGORATE SINUSES: Each spray helps clear nasal congestion with a potent dose of propolis, oregano oil, eucalyptus, xylitol, and saline so you can breathe deeply. Our effective nasal spray expands the nasal passage to cleanse and clear congestion. It flushes the sinuses irritants such as pollen, pollution etc.
- INVIGORATING PLUS FORMULA: This powerful formula is crafted with propolis, oregano oil, eucalyptus, xylitol, and saline to clear nasal congestion and passages.
- NON-HABIT FORMING: Made with natural ingredients, this nasal spray can be effective against itchy, irritated nasal passages without the use of chemicals, such as steroids and drugs. It acts as a natural solution that expands airways and reduces swelling.
- HOW TO USE: Shake well. Squeeze twice and blow nose gently to clear mucus.
- HOW WE SOURCE: We never overharvest from our hives and always ensure that our green apiaries are remote and far from harmful chemicals.
$13.99
Mucinex Sinus-Max Severe Nasal Congestion Relief Sinus & Allergy Nasal Spray, 0.75 Fluid Ounce
- MUCINEX OVER-THE-COUNTER NASAL SPRAY: Mucinex Sinus-Max Severe Nasal Congestion Relief helps relieve nasal congestion, sinus congestion, and sinus pressure
- NASAL SPRAY DECONGESTANT: A blast of Oxymetazoline HCI, a powerful topical nasal decongestant, that starts working immediately and provides nasal congestion relief for up to 12 hours
- NOSE SPRAY SINUS MEDICINE FOR SINUS RELIEF: Mucinex Sinus Max nasal spray applies a targeted nasal mist directly to your nasal passages to help clear sinus congestion fast
- NASAL DECONGESTANTS FOR ADULTS: Use as directed, for adults and children ages 6+ (with adult supervision)
- SINUS & ALLERGY SYMPTOM RELIEF: Powerful relief from nasal and sinus congestion due to common cold, hay fever, other respiratory allergies
$13.99
Mucinex Sinus Saline Nasal Spray & Sinus Rinse, Drug-Free, Additive Free, Non-Drowsy Nasal Irrigation with 2-in-1 Jet + Mist Spray Nozzle for Cold & Allergy Season, 4.5oz
- SALINE NASAL SPRAY: Mucinex Sinus Saline Nasal spray is designed to help clear congestion associated with colds & year-round allergies; Our unique 2-in-1 nozzle features a powerful jet for tough congestion & a gentle mist for everyday congestion
- SINUS RINSE: A saline nasal rinse that's non-medicated, non-drowsy, has no additives & is safe for daily use for adults & children 2 years of age and older
- NASAL IRRIGATION SYSTEM: A powerful solution for clearing nasal congestion; Our saline spray is formulated to soothe and moisturize your sinuses, providing effective relief; Breathe easy and conquer sinus congestion today
- OVER-THE-COUNTER SALINE SOLUTION: Targeted relief meets soothing moisture in every spray; Elevate your sinus care routine and enjoy the revitalizing benefits of our saline solution
- TRUSTED BRAND: Mucinex is the #1 Cough & Cold Brand Doctor's Trust* and is also the #1 Pharmacist Recommended Brand**; Get the brand that doctors trust and recommend
$8.99
SALE
−$0.70
Xlear Nasal Spray with Xylitol, 1.5 fl oz (Pack of 1)
- NATURAL SALINE SOLUTION & NASAL RINSE: Our nasal saline spray will gently clean and moisturize the sinus tissues. Unlike other normal saline nasal sprays our spray can also decongest the sinuses by targeting the primary causes of nasal congestion. Our nose spray will help reduce tissue swelling from pollen, pollution, contaminants, and other irritants.
- SAFE NASAL RINSE & SPRAY: Our all-natural nasal cleaner is safe for kids, non-addictive, Non-GMO Project Verified and is effective without the use of steroids, drugs, or chemicals. It is the ideal daily sinus medicine that will reduce swelling and open your airways. Using our saline nose spray before bed may reduce snoring.
- IMPROVED FORMULA WITH XYLITOL: Our patented saline nasal spray solution may reduce tissue inflammation and naturally open airways. Xylitol's powerful oral and upper respiratory health benefits come from its unique five-carbon structure. Xylitol may help reduce swelling and allergy symptoms by reducing contaminant adhesion on your nasal tissue.
- EASY TO USE DIRECTIONS: Clear the nasal passageway by gently blowing your nose before using Xlear. Prime the pump by holding the sinus rinse bottle upright and pumping one or more times until the saline solution is dispensed. Insert nozzle into nostril and depress pump completely while breathing in through your nose. Spray each nostril 2-4 times and use at least twice daily.
- WASH AWAY POLLUTANTS: Our natural saline nasal spray can wash away pollutants and help to bring sinus relief. Use our sinus spray daily to protect and keep your nasal passages clean. Each 1.5 oz bottle delivers approx. 240 fine mist Sprays so you can find fast and quick relief.
$11.79
Afrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)
- Ridiculously Fast Relief: Unblock your nose in seconds with Afrin No Drip Severe Congestion Nasal Mist, a fast-acting nasal pump mist decongestant providing sinus pressure and congestion relief with cooling menthol in a convenient twin pack
- Effective for Severe Congestion: This maximum strength nasal spray is perfect for relieving severe nasal congestion and sinus pressure caused by colds and allergies, offering quick and effective stuffy nose relief for adults and children 6 years and older
- No Drip Technology: Afrin's No Drip technology ensures the medicated mist stays where it's sprayed, providing effective nasal decongestion without the mess or discomfort of it dripping from your nose or down your throat
- Cooling Menthol Formula: Experience the soothing and cooling sensation of menthol while the powerful decongestant works to constrict blood vessels in the nasal passages and reduce swelling to help you breathe easier
- 12-Hour Non-Drowsy Decongestion: Experience long-lasting relief for up to 12 hours without drowsiness, perfect for both day and night use to alleviate nasal congestion and provide sinus pressure relief
$16.46
Flonase Allergy Relief Nasal Spray, 24-Hour Non-Drowsy Multi-Symptom Relief 144 Sprays, Bonus Pack of Tissues
- One 144-spray bottle of Flonase Allergy Relief Nasal Spray, 24-hour non-drowsy allergy medicine, metered nasal spray plus Bonus Pack of Tissues
$27.99
TriGuard Plus Colloidal Silver Nasal Spray with Olive Leaf Extract & Elderberry Extract | Sinus Treatment, Nose Spray & Immune System Booster 2 oz / 60ml, Made in USA (Packaging May Vary)
- UNIQUE INGREDIENTS: Nasal Spray Carefully crafted with our signature OLE-100 Complex contains a blend of Structured Colloidal Silver Water, Olive Leaf Extract and European Sambucus Elderberry which works to support your body's natural immune response. All ingredients use alcohol and a chemical solvent free extraction process.
- STRUCTURED NASAL SPRAY | A natural sinus remedy that may strengthen the immune system.
- ELDERBERRY & OLIVE LEAF EXTRACT: Premium 40:1 Oleuropein Standardized Herbal Extract is used for immune support. Sourced from European Black Elderberry Fruit, this powerful immunity booster is packed with antioxidants and vitamins that can tame Immune issues.
- INSTRUCTIONS | Use as needed or as directed by a physician. Head held upright, insert spray nozzle into nostril. Adults, depress pump completely 1-2 times
- DAILY RELIEF | Repeat up to 3 times daily. Enjoy the congestion relief throughout the day, and wipe the nozzle clean after each use to preserve longevity. ** MADE IN THE USA** Packaging May Vary
$19.89
Last update on 2025-05-31 / Affiliate links / Images from Amazon Product Advertising API