Nasal spray is an essential product for many individuals seeking relief from congestion, allergies, or sinus issues. In 2025, the market offers a variety of options that cater to different needs, ensuring that users can find the perfect solution for their symptoms. From saline sprays to medicated options, the best nasal sprays are designed to provide quick and effective relief, making them a staple in many households. Whether you're dealing with seasonal allergies or a stubborn cold, these top-rated sprays can help you breathe easier and feel better.
Arm & Hammer Simply Saline Daily Care Nasal Mist 4.4oz, Saline Nasal Spray, Drug-Free, 2-Pack
- Starts working in seconds!
- Helps relieve dryness
- Moisturizes and helps flush irritants from nasal passages
- A drug-free nasal spray that contains no steroids, made with simple and safe ingredients such as purified water, salt, and ARM & HAMMER Baking Soda
- Safe to use day and night, during pregnancy, and doctor-recommended for use with prescription and OTC medications
$14.79
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−$2.52
Vicks Sinex SEVERE Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Stuffy Nose due to Cold or Allergy, & Nasal Congestion, Sinus Pressure Relief, 265 Sprays x 2
- Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses
- Breathe better all day or all night long with Vicks Sinex Severe. For instant, 12-hour, nasal congestion and sinus pressure relief
- This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell, Not intended for daily use
- Unlike nasal decongestant tablets, Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes
- Vicks Sinex Severe Nasal Spray is HSA and FSA eligible, Check with your provider for more details
$14.97
Amazon Basic Care No Drip Severe Congestion Nasal Pump Mist Spray, 12 Hour Relief, Oxymetazoline HCl, Maximum Strength Plus Menthol, Steroid Free, 1 fl oz (Pack of 1)
- ACTIVE INGREDIENT: This nasal spray contains oxymetazoline HCl, a nasal decongestant and the doctor recommended adult nasal spray active ingredient (source: IQVIA physicians survey 2019), which compares to the active ingredient in Afrin No Drip. Offers maximum strength nasal congestion relief.
- 12 HOUR, MAXIMUM STRENGTH RELIEF: Amazon Basic Care Severe Congestion Nasal Spray, Oxymetazoline HCl provides 12 hours of maximum strength nasal congestion relief due to the common cold, hay fever and upper respiratory allergies.
- FAST NASAL CONGESTION RELIEF: Amazon Basic Care Severe Congestion Nasal Spray, Oxymetazoline HCl provides fast and powerful relief for colds and allergies. Temporarily relieves sinus congestion and pressure.
- NASAL RELIEF: Amazon Basic Care Severe Congestion Nasal Spray, Oxymetazoline HCl provides temporary nasal congestion relief by shrinking swollen nasal membranes so you can breathe more freely.
- NO DRIP NASAL SPRAY: This cold and allergy relief nasal spray won't drip down your nose or throat. Severe congestion formula pump mist. Safety Sealed. This product is gluten free. Contains Menthol.
$4.89
Afrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)
- Ridiculously Fast Relief: Unblock your nose in seconds with Afrin No Drip Severe Congestion Nasal Mist, a fast-acting nasal pump mist decongestant providing sinus pressure and congestion relief with cooling menthol in a convenient twin pack
- Effective for Severe Congestion: This maximum strength nasal spray is perfect for relieving severe nasal congestion and sinus pressure caused by colds and allergies, offering quick and effective stuffy nose relief for adults and children 6 years and older
- No Drip Technology: Afrin's No Drip technology ensures the medicated mist stays where it's sprayed, providing effective nasal decongestion without the mess or discomfort of it dripping from your nose or down your throat
- Cooling Menthol Formula: Experience the soothing and cooling sensation of menthol while the powerful decongestant works to constrict blood vessels in the nasal passages and reduce swelling to help you breathe easier
- 12-Hour Non-Drowsy Decongestion: Experience long-lasting relief for up to 12 hours without drowsiness, perfect for both day and night use to alleviate nasal congestion and provide sinus pressure relief
$16.49
Amazon Basic Care Premium Saline Nasal Moisturizing Spray, 1.5 fl oz (Pack of 1), Clear
- COMPARE AND SAVE: Compare to the ingredients in Ocean. Amazon Basic Care Premium Saline Nasal Moisturizing Spray contains sodium chloride 0.65%, phenylcarbinol and benzalkonium chloride as preservatives.
- SOOTHES DRY NASAL PASSAGES: This saline nasal spray relieves dry nasal membranes.
- SALINE NASAL SPRAY provides non-medicated relief for irritated and dry nasal passages.
- RELIEVES DRYNESS from allergy, sinus and cold medications. Instantly soothes dry nasal passages.
- CAUTION: Keep Amazon Basic Care Premium Saline Nasal Moisturizing Spray out of reach of children. The use of this nasal moisturizing spray dispenser by more than one
$4.00
Afrin No Drip Extra Moisturizing 12 Hour Nasal Congestion Relief Pump Mist, Sinus Spray Decongestant - 15 mL
- Afrin No Drip Extra Moisturizing is a nasal pump mist designed to relieve nasal congestion for up to 12 hours
- Nasal decongestant pump mist works instantly to provide nasal and sinus congestion relief caused by allergies or other nasal irritants.
- Medicated no drip nasal spray doesn’t drip from your nose or down your throat
- 12 hour medicated moisturizing nasal spray soothes dry nasal passages
- Use Afrin nasal mist as directed, spraying two or three times into each nostril for no more than three days
$9.46
Flonase Allergy Relief Nasal Spray, 24-Hour Non-Drowsy Multi-Symptom Relief – 144 Sprays, Bonus Pack of Tissues
- One 144-spray bottle of Flonase Allergy Relief Nasal Spray, 24-hour non-drowsy allergy medicine, metered nasal spray plus Bonus Pack of Tissues
- Flonase Allergy Relief Nasal Spray is a 24-hour non-drowsy allergy medicine that blocks 6 allergic substances to stop your body from overreacting to allergens
- Containing fluticasone propionate, the most prescribed allergy medication (2), Flonase relieves nasal congestion plus runny nose, sneezing, itchy nose, and itchy, watery eyes (1)
- Number 1 doctor recommended allergy brand delivers long-lasting full prescription strength relief from allergies
- Works year-round to relieve indoor and outdoor allergy symptoms caused by allergens including pollen, mold, dust mites and pet dander
$27.99
Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)
- ACTIVE INGREDIENT: This nasal spray contains oxymetazoline hydrochloride 0.05%, a nasal decongestant. Compare to the active ingredient in Afrin Original.
- PURPOSE: This nasal spray temporarily relieves nasal congestion, sinus congestion and pressure due to the common cold, hay fever and upper respiratory allergies.
- 12 HOUR RELIEF: Amazon Basic Care Maximum Strength Nasal Spray provides fast, powerful congestion relief for allergies and colds for up to 12 hours.
- FAST CONGESTION RELIEF: Provides fast and powerful nasal congestion relief for allergies and colds.
- FAST-ACTING NASAL DECONGESTANT clears stuffy nose due to upper respiratory allergies and the common cold.
$6.71
HealthA2Z Fluticasone Propionate Nasal Sprays, 24 Hour Allergy Relief,120 Sprays, 0.54 fl oz
- 24-HOUR ALLERGY RELIEF: HealthA2Z Fluticasone Propionate Nasal Spray temporarily relieves symptoms of hay fever or other upper respiratory allergies: Itchy, Watery Eyes, Nasal Congestion, Runny Nose, Itchy Nose, Sneezing.
- NON-DROWSY: A non-drowsy nasal spray that allows you to go about your day with all day relief from common allergy symptoms.
- WARNINGS: only for use in the nose. Do not spray into your eyes or mouth.
- DIRECTIONS: Week 1: use 2 sprays in each nostril daily/Week 2 through 6 months: use 1 or 2 sprays in each nostril once daily, as needed to treat symptoms/After 6 months of daily use: ask a doctor if you can keep using.
$14.45
Amazon Basic Care Nasal Four Nasal Spray, Phenylephrine Hydrochloride 1 Percent, Nasal Decongestant, 1 fl oz (Pack of 1)
- ACTIVE INGREDIENT: Amazon Basic Care Nasal Four Nasal Spray contains phenylephrine hydrochloride 1%, a nasal decongestant, which compares to the active ingredient in 4-Way.
- FAST-ACTING NASAL SPRAY: Amazon Basic Care Nasal Four Nasal Spray contains a nasal decongestant that delivers fast relief of nasal congestion for up to four hours.
- MULTI-SYMPTOM RELIEF: Amazon Basic Care Nasal Four Nasal Spray relieves nasal congestion, swollen nasal membranes, sinus congestion and sinus pressure.
- NON-DROWSY NASAL CONGESTION RELIEF: Amazon Basic Care Nasal Four Nasal Spray provides non-drowsy relief for nasal symptoms so that you can get through your day.
- FOR AGES 12 YEARS AND OLDER: Amazon Basic Care Nasal Four Nasal Spray provides fast nasal congestion relief for adults and children ages 12 years and older.
$12.27
Last update on 2025-05-04 / Affiliate links / Images from Amazon Product Advertising API