Muscle pain relief cream is an essential remedy for anyone seeking quick and effective relief from soreness and discomfort. In 2025, the market is flooded with options, but the 10 best muscle pain relief creams stand out for their powerful formulations and user satisfaction. These creams often combine natural ingredients with advanced pain-relieving compounds, providing targeted relief for muscle strains, joint pain, and inflammation. Whether you’re an athlete recovering from a workout or someone dealing with chronic pain, these top-rated products can help you regain mobility and comfort.
Pomada Dragon Ultra Strength Pain Relief Cream, Strength Muscle Rub for Joint, Shoulder, Knee Pain, Sore Muscle Relief, Topical Analgesic with Camphor & Menthol, 2 Oz
- [ PAIN RELIEF CREAM ]: Ultra over-the-counter strength muscle rub for shoulder pain relief, joint pain relief, and muscle pain relief. Deep-penetrating muscle pain relief cream for fast sore muscle relief
- [ DEEP HEAT PAIN RELIEF ]: Ultra-strength pain relief cream designed for deep penetration, providing relief from sore muscles, joint pain, and shoulder pain. Perfect for post-workout or injury recovery
- [ MULTIPURPOSE FORMULA ]: Effective muscle rub for fast muscle pain relief, shoulder pain relief, and tendonitis relief. Joint pain relief cream for lasting comfort
- [ ACTIVE INGREDIENTS ]: Formulated with Camphor 4%, Menthol 10%, and Methyl Salicylate 30% for powerful pain relief cream. Provides fast-acting muscle rub and joint pain relief with a deep-penetrating formula
- [ DOSAGE INSTRUCTIONS ]: Apply a thin layer of pain relief cream to affected area 3-4 times daily. Massage gently for muscle pain relief, joint pain relief, and fast-acting muscle rub relief
$6.88
SALE
−$4.27
Boiron Arnicare Gel for Soothing Relief of Joint Pain, Muscle Pain, Muscle Soreness, and Swelling from Bruises or Injury - Non-greasy and Fragrance-Free - 2.6 oz
- ARNICA FOR PAIN: This homeopathic medicine helps temporarily relieve muscle pain & stiffness due to minor injuries, overexertion & falls. Also great for pain, swelling, & discoloration from bruises.
- TOPICAL PAIN RELIEF: Our non-greasy, water-based formula absorbs quickly & is unscented & paraben-free. This cooling gel is great for relief following an injury, intense workout, or general overexertion.
- PLANT-BASED ACTIVE INGREDIENT: The Arnica montana plant is a natural pain reliever. This popular homeopathic medicine temporarily relieves muscle pain & stiffness without unwanted drowsiness.Fluoride-Free
- HOMEOPATHIC MEDICINE uses highly diluted biological, botanical, or mineral substances to relieve symptoms. Our tablets, pellets, & topical treatments work with your body without the risk of contraindications, or known drug interactions.
- THE BOIRON PROMISE: We believe there’s more than one way to feel better. Since 1932, we have been committed to providing quality medicines. As a world leader in homeopathy, our passion is your health. Our promise is your satisfaction.
$8.32
SALE
−$3.00
Biofreeze Menthol Pain Relieving Cream 3 OZ Jar for Pain Relief Associated with Sore Muscles, Arthritis, Simple Backaches, Strains, Bruises, Sprains and Joint Pain (Packaging May Vary)
- #1 Clinically Recommended Menthol Topical Pain Relief Brand
- Biofreeze Menthol Pain Relieving Cream is non-greasy with natural moisturizers and penetrates for pain relief
- Fast acting, cooling menthol formula delivers and penetrating pain relief for minor aches and pains of muscles and joints associated with simple backache, arthritis, strains, bruises, and sprains
- This 3 oz. cream jar comes in TSA-approved sizing for hassle-free travel or on the go pain relief
- Biofreeze is a clinically recommended brand; trusted by pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers
$11.99
Advil Targeted Relief Pain Relieving Cream, Up to 8 Hours of Powerful Relief of Minor Arthritis Pain, Joint Pain, Lower Back Pain and Muscle Pain - 2.3 oz
- One 2.3 oz Tube of Advil Targeted Relief Pain Relieving Cream - The only topical pain reliever with 4 powerful pain-fighting ingredients (1)
- Provides a warming & cooling sensation on contact and lasts up to 8 hours (1)
- Designed to quickly tackle pain four ways: targets, penetrates, blocks, and relieves
- Fast and powerful relief for minor arthritis pain, muscle, joint and back pain - the perfect addition to your college dorm room essentials
- Doesn't leave your skin feeling dry or greasy and easily glides onto skin, ensuring comfort with every use
$10.98
(3 Pack) Globe Ultra Strength Greaseless Muscle Rub Cream (3 oz). Compare to The Active Ingredients of Greaseless Bengay, 10% Menthol & 15% Methyl Salicylate (3 Pack)
- WHAT'S INSIDE: Globe Ultra Strength Greaseless Muscle Rub Cream contains Menthol 10% and Methyl Salicylate 15% for Fast Relief of Muscle Aches, Back Aches, Joint Aches and Arthritis.
- TEMPORARY RELIEF: Temporary Rapid Relief from the minor aches and pains of muscles and joints associated with backache, arthritis, strains, bruises and sprains.
- FAST RELIEF: Globe Ultra Strength Greaseless Pain-Relieving Cream is formulated for fast and sustainable pain relief.
- FRONT LINE PAIN RELIEF: What you need to know: Globe Ultra Strength Greaseless Muscle Rub Gel is a safe and effective home remedy and useful in any home, gym, sports bag, car or camping first aid kit.
- PHARMACISTS RECOMMENDED: Pharmacist recommend Globe Ultra Strength Greaseless Pain Relieving Rub because of the power of its penetrating pain relief.
$11.99
Icy Hot Max Strength Pain Relief Cream with Lidocaine Plus Menthol, 1.75 Ounces
- Includes one (1) 1.75-oz. tube of Icy Hot Max Strength Pain Relief Cream With Lidocaine Plus Menthol
- Icy Hot Lidocaine Cream desensitizes aggravated nerves to temporarily relieve minor pains associated with foot pain, back pain, muscle pain, knee pain and arthritis pain
- This pain cream penetrates to the nerves for quick relief in minutes that lasts for hours
- Apply non-greasy Icy Hot Pain Relieving Cream With Lidocaine Plus Menthol to the affected area every 6-8 hours; do not exceed 3 applications in a 24-hour period
- Icy Hot is the number-one topical pain relief brand* *among OTC topical analgesics
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Penetrex Soothing Joint & Muscle Pain Relief Cream with Hemp - Deep Penetrating Menthol, Arnica and Hemp for Soothing, Hydrating Relief - Non-Greasy, Easy to Apply, Pleasant Scent- 2oz Squeezable Tube
- DEEP PENETRATING PAIN RELIEF: From the makers of Penetrex comes a soothing addition to your relief regimen. Our non-prescription muscle pain relief cream provides soothing relief from aches and pains associated with arthritis, sprains & strains, and knee, neck, elbow, and back discomfort.
- UNIQUE FORMULA: Pain relief cream made with our proprietary blend of ingredients; menthol soaks into the body and soothes while hemp and arnica provide moisturizing relief; boswellia serrata aids with overall joint health supplemented by vitamin B6
- PLEASANT, SOOTHING COMFORT: This premium, non-greasy hemp cream lightly soothes and provides moisturizing comfort for joints and muscles; joint pain relief cream made with a mild, pleasant scent that disappears with time
- USAGE: Hemp cream (maximum strength) temporarily relieves minor aches and pains associated with backache, arthritis, strains, bruises and sprains; apply to affected area no more than 3-4 times per day
- TRUST IN PENETREX: Enabling you to get back to your favorite activities with the premium experience in joint & muscle relief; eliminate the limitations of joint and muscle discomfort with Penetrex
$18.95
Nature's Willow Willow Balm Natural Pain Relief Cream for Muscles & Joints | Fast-Acting with Willow Bark & Menthol | Free from Artificial Fragrances & Dyes | 1-Pack | 3.5 fl oz
- Fast, Natural Relief: Infused with Willow Bark, Nature's Willow Pain Cream provides quick, effective relief for sore muscles and joints.
- Clean & Safe: Free from artificial fragrances, dyes, parabens, and phthalates for gentle yet effective care.
- Why Willow Bark Works: Rich in salicin, willow bark has natural soothing properties that help provide effective relief.
- Targeted, Convenient Relief: Soothe aches and pains instantly, on the go.
- Made in North America
$9.99
Biofreeze Pain Relief Gel, Arthritis Pain Reliver, Knee & Lower Back Pain Relief, Sore Muscle Relief, Neck Pain Relief, Pharmacist Recommended, FSA Eligible, 3 FL OZ Biofreeze Menthol Gel
- #1 Clinically Recommended Menthol Topical Pain Relief Brand
- This 3 fl oz gel tube is one of the most popular formats, well-suited for application on small and large muscle areas
- Biofreeze is a clinically recommended brand; trusted by pharmacists, physical therapists, chiropractors, massage therapists, podiatrists, and athletic trainers
- Product is not tested on animals, made with USP grade menthol, and free of NSAIDs
- Product is not tested on animals, made with USP grade menthol, and free of NSAIDs
$11.98
MagniLife Leg & Back Pain Relief Cream, Fast-Acting Pain Relief, Naturally Soothe Burning, Tingling and Stabbing Pains with Aloe and Calendula - 4oz
- HOW TO USE - Constant pain in your lower body can be distracting and debilitating. A pain reliever developed to specifically target symptoms in the lower back, buttocks and legs. Results may vary. For best results, this topical cream should be used twice daily for a sustained period of time, applying generously and massaging into skin to help ease burning, tingling and stabbing pains in your lower body.
- INTENSE NATURAL INGREDIENTS - Naturally derived blend soothes aching, uncomfortable pain in legs and back with aloe, lavender, magnesium, geranium, sweet and chili peppers, colocynth and calendula. Our deep penetrating cream contains active ingredients to help deliver fast-acting, serious relief when you need it most.
- NOTHING ADDED BUT THE GOOD STUFF - This quick absorbing, non-greasy cream penetrates deeply. Safe to use on sensitive skin with no added dyes or fragrances.
- SAFE TO USE WITH OTHER PAIN RELIEVERS - Topical formulas can be used in conjunction with other OTC pain relievers or medications.
- TRUSTED BRAND WITH YOU IN MIND - MagniLife has been a trusted business for over 25 years. All of our products are developed and manufactured in our state-of-the art facilities. Made with highly qualified formulators to ensure excellence in quality and consistency, we ensure top quality products and are dedicated to providing products that help to improve quality of life. Start your journey to a healthy lifestyle today!
$11.97
Last update on 2025-06-01 / Affiliate links / Images from Amazon Product Advertising API