Migraine medicine has evolved significantly, offering a range of effective treatments for those suffering from debilitating headaches. In 2025, the best options include a variety of prescription medications, over-the-counter solutions, and innovative therapies that target migraine symptoms at their source. From triptans to CGRP inhibitors, these medications provide relief and improve the quality of life for many individuals. With ongoing research and development, the future of migraine treatment looks promising, ensuring that patients have access to the most effective options available.
Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms - 200 Count
- One bottle of 200 Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms
- Excedrin Migraine works in 3 ways to relieve migraines: it blocks pain signals, elevates your pain threshold and uses caffeine to enhance the pain relief effect
- Delivers migraine relief, including acting as a migraine headache pain reliever and relieving sensitivity to light and sound, and nausea
- Excedrin migraine pain relief caplets combine acetaminophen, aspirin and caffeine
- Head pain relief medicine delivers a powerful triple action formula with two pain relievers and an amplifier
$19.73
Amazon Basic Care Migraine Relief Geltabs, Acetaminophen, Aspirin (NSAID) and Caffeine, 80 Count
- ACTIVE INGREDIENTS: This product contains acetaminophen 250 mg, aspirin 250 mg (NSAID: nonsteroidal anti-inflammatory drug) and caffeine 65 mg. Compare to the active ingredients of Excedrin Migraine Geltabs
- PAIN RELIEF: Amazon Basic Care Migraine Relief Geltabs offer headache pain relief so you don't miss out on life's special moments
- MIGRAINE TREATMENT: Just one dose helps to temporarily reduce headache pain caused by migraines
- PAIN RELIEVER AND PAIN RELIEVER AID: Amazon Basic Care Migraine Relief Geltabs combine acetaminophen 250 mg, aspirin 250 mg (NSAID: nonsteroidal anti-inflammatory drug) and caffeine 65 mg to treat migraine pain
- GLUTEN FREE: These headache pain relief pills are gluten free
$9.04
Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms - 24 count
- One bottle of 24 Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms
- Migraine medicine that delivers effective migraine headache pain relief
- Delivers migraine relief, including acting as a migraine headache pain reliever and relieving sensitivity to light and sound, and nausea
- Excedrin migraine pain relief caplets combine acetaminophen, aspirin and caffeine
- Delivers a powerful triple action formula with two pain fighters and an amplifier
$4.97
SALE
−$2.03
Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms - 24 count
- One bottle of 24 Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms
- Migraine medicine that delivers effective migraine headache pain relief
- Delivers migraine relief, including acting as a migraine headache pain reliever and relieving sensitivity to light and sound, and nausea
- Excedrin migraine pain relief caplets combine acetaminophen, aspirin and caffeine
- Delivers a powerful triple action formula with two pain fighters and an amplifier
$4.97
GenCare - Tension Headache Relief Pain Reliever with Acetaminophen 500 mg & Caffeine 65 mg (200 Caplets) Best Value Bulk Extra Strength for Head, Migraine, Joint Pain & Body Ache Relief Medicine
- EXTRA STRENGTH RELIEF - Reach for GenCare extra strength Tension Headache Relief when suffering from mild to severe headaches, migraines, tension pain and muscle aches. Our full head and body pain remedy includes Acetaminophen (500 mg) pain reliever and Caffeine (65 mg) for focus and energy.
- DUAL ACTION - The potent dual action pain relief pill isn't just for mild to severe headaches. It provides fast and effective relief for sore muscles, tooth aches, back aches, neck pain, arthritis and joint pain. Compare to generic Excedrin Tension Headache active ingredients.
- MENTAL FOCUS - Caffeine can help quickly restore energy levels and focus so you can get over the pain and back to being productive and at your best. This product contains as much caffeine as a cup of coffee so avoid taking this before bed or at night.
- FAMILY VALUE SIZE - Save big compared to big box retailers and your local pharmacy with our 200 caplet bulk savings bottle. Directions: Adults and children 12 and older take 2 caplets every 6 hours as needed with water. For children under 12, ask a doctor before use.
- 100% SATISFACTION GUARANTEE - Enjoy fast and effective headache and muscle ache relief! GenCare backs up each bulk savings bottle of Tension Headache Relief with our 100% Customer Satisfaction Guarantee. Join thousands of satisfied customers.
$9.99
Amazon Basic Care Headache Relief Geltabs, 80 Count
- ACTIVE INGREDIENTS: This product contains acetaminophen 250 mg, aspirin 250 mg (NSAID, nonsteroidal anti-inflammatory drug) and caffeine 65 mg; compare to the active ingredients in Excedrin Extra Strength Geltabs
- PAIN RELIEF: Amazon Basic Care Extra Strength Headache Relief Geltabs offer headache and arthritis pain relief; also provides pain relief for toothaches, muscular aches and premenstrual and menstrual cramps
- EXTRA STRENGTH: When you need something strong to temporarily reduce pain, these extra strength geltabs will help you feel better so you don't miss out on life's special moments
- PAIN RELIEVER AND PAIN RELIEVER AID: Extra Strength Headache Relief Geltabs combine acetaminophen 250 mg, aspirin 250 mg (NSAID, nonsteroidal anti-inflammatory drug) and caffeine 65 mg to help relieve minor aches and pains when you need it the most
- GLUTEN FREE: These pain relief pills are gluten free
$10.07
GenCare - Headache Relief Acetaminophen with Aspirin (NSAID) & Caffeine (300 Caplets) Value Pack | Head Pain, Muscle Aches, Back Pain & Body | Generic Excedrin Extra Strength
- HEAD & BODY PAIN RELIEF - Each caplet of GenCare Extra Strength Headache Relief contains 250mg of Acetaminophen, 250mg of Aspirin (NSAID) and 65 mg of Caffeine to give fast and extended pain relief of headaches, muscle aches, back pain and migraines.
- HUGE SAVINGS - Save big compared to big box stores and your local pharmacy with effective over the counter relief with our bulk size 300 caplet value bottle. Always be prepared and in stock with effective pain relief pills on hand for when your family needs it the most. Compare to generic Excedrin Extra Strength active ingredients.
- ACTS FAST - Headaches, migraines and pain can hit at the worst time. 65 mg of caffeine in each pill help energize you and restore mental focus so you can accomplish the task at hand. 65 mg of caffeine is about as much a cup of coffee, so avoid this product before bed.
- HELPS WITH ACHES & PAINS - Relieve Back pain, neck pain, toothaches, menstrual cramps, arthritis, joint pain and more in one easy to swallow caplet. Directions: Adults and children 12 years and older : take 2 caplets every 6 hours . Do not exceed 8 caplets in a 24 hour period.
- 100% SATISFACTION GUARANTEE - Say goodbye to headaches and pain! GenCare backs up each bulk savings bottle of Extra Strength Headache Relief with our 100% Customer Satisfaction Guarantee. Join thousands of satisfied customers.
$13.99
SALE
−$2.87
Glaxosmithkline Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms - 100 Count
- One bottle of 100 Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms
- Excedrin Migraine works in 3 ways to relieve migraines: it blocks pain signals, elevates your pain threshold and uses caffeine to enhance the pain relief effect
- Delivers migraine relief, including acting as a migraine headache pain reliever and relieving sensitivity to light and sound, and nausea
- Excedrin migraine pain relief caplets combine acetaminophen, aspirin and caffeine
- Head pain relief medicine delivers a powerful triple action formula with two pain relievers and an amplifier
$12.99
Motrin IB Migraine Liquid Gel Caps, Ibuprofen 200 mg, Migraine Relief Medicine, 80 Ct
- 80-count bottle of Motrin IB Migraine Relief Liquid Gel Capsules with pain reliever ibuprofen for fast, effective relief from migraine headaches. Keep this travel size bottle in your purse or bag to tackle your migraine pains on-the-go
- Motrin IB Migraine liquid gels provide powerful pain relief when it counts to treat migraine headaches and migraine-related symptoms including nausea, sensitivity to light (photophobia) and sensitivity to sound (phonophobia)
- Each liquid gel contains 200 milligrams of the NSAID* pain reliever ibuprofen to help stop migraine pain. Motrin IB Migraine pain relief capsules work hard to stop migraine pain for powerful, effective pain relief *nonsteroidal anti-inflammatory drug
- This caffeine-free & dye-free migraine relief medicine is indicated for adults 18 years or older and is safe and effective when used as directed for migraine relief. If migraine headache pain is not relieved or gets worse after, contact your doctor
- Adults aged 18 or older, take two capsules with a glass of water; do not take more than two capsules in 24 hours unless directed by a doctor. These pain relief pills can be taken with food or milk if upset stomach occurs
$16.07
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API