Methylated multivitamins are essential for those seeking optimal health, especially for individuals with MTHFR gene mutations that affect folate metabolism. In 2025, the 10 best methylated multivitamins stand out for their high-quality ingredients, bioavailability, and comprehensive nutrient profiles. These supplements not only support energy levels and immune function but also promote mental clarity and overall well-being. With a focus on methylated forms of vitamins B12 and folate, these products ensure that your body can effectively utilize the nutrients for maximum benefit.
10X Health Optimize Methylated Multivitamin for Men & Women - 34 in 1 Formula with 800 mcg of Vitamin B12, Vitamin E, 5-MTHF, B Complex, NAC, Magnesium & Zinc Multivitamins - 90 Capsules
- Targeted Nutritional Support: 10x Optimize methylated multivitamins offer the ultimate multivitamin and mineral formula to address genetic deficits in your methylation pathway. This impacts your overall wellness and supports optimal health.
- Essential Methylated Nutrients: This includes crucial methylated vitamins like 5-MTHF (methylated folic acid), methylated B12, riboflavin (B2), and pyridoxine (B6). This multivitamin-methylated formula supports your body's natural methylation processes.
- Vital Minerals for Balance: Formulated with optimized minerals such as magnesium and zinc, 10X Optimize multivitamins for women and men help to maintain essential mineral balance and support the immune system, energy production, and cognitive function.
- Additional Methylation Support: Contains NAC (N-acetyl L-cysteine), a powerful amino acid known for its excellent support of the methylation pathway. NAC helps boost your body's ability to boost antioxidant levels and promote cellular health.
- Quality and Safety Focused: The 10X Optimize methylated multivitamin from 10X Health System is proudly made in the USA using premium, carefully sourced ingredients. Each batch undergoes rigorous quality and purity testing, ensuring your wellness.
$53.00
Methylated Multivitamin (Methylated and Activated Vitamins Only - Methylated B Complex with Trimethylglycine (TMG) and Methylfolate)(Non-GMO, Gluten Free MTHFR Supplement) 120 Capsules by Double Wood
- METHYLATED FORMS OF VITAMINS: Double Wood's Methylated Multivitamin contains only methylated / activated forms of vitamins that are already usable by the body and do not need to be further converted in order to be bioavailable
- METHYLATED B COMPLEX: Contains the Methylated / Activated Coenzyme form of Vitamin B2 (R-5-P), Vitamin B6 (P-5P) and Vitamin B12 (Methylcobalamin and Dibencozide)(Methyl B12)
- SIX TOTAL METHYLATED VITAMINS: Contains trimethylglycine and calcium L-5-methyltetrahydrofolate (MTHFR multivitamin) to help support healthy folic acid levels and control homocysteine levels in the body. It is important to use methylated folic acid since standard folic acid is inert in the body and cannot be processed further by many people
- CAN COMBINE WITH A NORMAL MULTIVITAMIN: Double Wood's Methylated Multivitamin can be combined with a regular multivitamin for those looking to also supplement with inactive vitamins or vitamins such as Magnesium and Vitamin D
- WE BOTTLE WELLNESS: At Double Wood we provide pure, potent supplements that deliver exceptional value, all backed by careful sourcing and rigorous third-party testing
$24.95
SALE
β$2.50
envitamin Methylated Multivitamin Multimineral Complex L Methylfolate
- Methylated Multivitamin Complex By envitamin with L Methylfolate
- Methylated B12, 5-MTHF, Inositol, & Lycopene
- Contains the micronutrients you need for your body
$22.47
Pure Methylated Multivitamin for Men & Women | 240 Capsules with Vitamins C, D, B12, Thiamin, Folate + Magnesium, Zinc, & More | High Absorption | Bioactive Vitamin & Mineral Complex | Filler Free
- Micro Ingredients offers a Pure Methylated Multivitamin Complex. 19-in-1 support with high absorption bioactive forms. 240 capsules that feature raw, active ingredients with no fillers.
- Each serving provides active methylated vitamins like fat-soluble vitamin C (ascorbyl palmitate), A (retinyl palmitate), D3 (cholecalciferol), E (d- alpha tocopherol), thiamin HCl, riboflavin (R5P), niacin (niacinamide), B6 (P5P), folate, B12 (methylcobalamin), biotin, and pantothenic acid.
- An advanced multivitamin combined with key minerals for promoting various health benefits that include energy, cellular, heart, immune, and brain support for men and women.
- Enjoy only active ingredients that use high bioavailable methylated vitamins and minerals for efficiently refilling key nutritional gaps over time.
- Premium non-GMO multivitamins supplement. Made without fillers, soy, dairy, wheat, gluten, fish, shellfish, peanuts, and tree nuts. Ingredients must pass our 3rd party lab tests to ensure a product that is safe, pure, and potent.
$24.99
Methyl Multi Without Iron Methylated Multivitamin for Men & Women, 60-Day Supply | Methyl B12 & Methylfolate (5-MTHF) for MTHFR Support | Pharma Grade Multivitamin & Multimineral For Health, 120 Caps
- πππππππ πππππ ππππππππ: Discussed on The Joe Rogan Experience with Gary Brecka, Methyl Multi without Iron is a vegan-friendly, hypoallergenic, and meticulously-researched multivitamin and multimineral supplement made from high-quality ingredients with zero fillers. Our comprehensive formulation promotes healthy cognitive function and supports antioxidant protection and detoxication. Methyl Multi is the ultimate multivitamin to support total-body wellness and optimum vitality.
- πππππππ ππππππππππ: When supplementing, absorption is key! Methyl Multi without Iron is formulated with Quatrefolic Folate (5-MTHF), Albion TRAACS mineral chelates, and other micronutrients in their pre-methylated and coenzyme forms for optimal absorption and bioavailability, all together in DRcaps acid resistant vegetable capsules.
- ππππππππ ππππ π πππππππ: Millions of Americans have MTHFR and/or COMT mutations, making it difficult for their bodies to process key vitamins like B12 and Folate. Methyl Multi without Iron contains pre-methylated forms of B12 and Folate for increased bioavailability, which can help to support healthy metabolism, energy release from food, detoxification, and nervous system function.
- πππ ππ πππππππππππ? For those extremely sensitive or new to methylated vitamins, we recommend gradually increasing the amount you are taking so your body can adapt. A small percentage of customers can experience a temporary detoxification / Herxheimer response. Symptoms may include: headache, lethargy, skin rash / hives, respiratory symptoms (cough, sore throat). These are temporary and a sign that the supplement is working. However if your body detoxes too quickly at one time it can overload your detox pathways! Itβs imperative to lower the amount you are taking for a few days and work your way up slowly to the full dose βLOW & SLOWβ
- ππ πππππ πππππ πππππππππππ: Pure TheraPro Rx Methyl Multi without Iron contain no fillers such as rice flour, cornstarch, or wood pulp fibers. Our manufacturing facility adheres to strict NSF/cGMP guidelines. Consumer safety and satisfaction are our highest priority, which is why our products undergo rigorous third-party testing and screening to ensure product purity and potency.
$43.47
Inessa Methylated Multivitamin for Men and Women - Advanced Natural Daily Mens Multivitamins with CoQ10 100mg, Vitamins D3, K2, A, B Complex Vitamins, Folic Acid & Zinc - 60 Vegan Tablets
- [Feel Like You, But Better] You want to thrive, not just survive. You want best, not just better, health. So meet the cutting-edge multivitamin supplement designed with your optimal wellness in mind. This magical multivitamin with K2 and vitamin D3 is productivity powerhouse that keeps you feeling fresh and focused, all-day-long.
- [Daily Wellness, Simplified] - Why take multiple supplements to get everything you need? This one-a-day wonder has 25 ingredients in highly bioavailable doses crammed into every dose. Itβs one of the only multivitamins that works like an antioxidant complex, B-complex, CoQ10, vitamin D3 and vitamin K2 supplement in one.
- [Vegan Society Approved] Eating clean? We hear you. This women's and menβs vegan multivitamin is also allergen, gluten and dairy free. But donβt just take our word for it. We batch test our multivitamin supplement for purity and it contains no unnecessary additives, chemicals, flavorings or color.
- [Fights Fatigue] Micronutrient deficiencies can impact your vitality, and even healthy diets may not give you everything you need for boundless energy. But with relevant doses of CoQ10, B-complex vitamins, D3, iodine and more, this women's and menβs multivitamin will put the natural spring back into your step.
- [Nature's Nourishment] - Embrace a natural approach to wellness with our gluten-free, vegan multivitamin. Crafted for modern men like you, it champions your dietary choices while enriching your health journey. Make every day a step toward a healthier, happier you!
$39.99
Igennus Methylated Men's Multivitamin, MTHFR Supplement with Active B-Vitamins, 22 Highly Bioavailable Nutrients, Multivitamin for Sustained Release, Clean Label, Non-GMO & Halal 60 Tablets
- METHYLATED & ACTIVE FORMS - each nutrient form has been carefully selected to optimize the journey from supplement to cell. Includes methylated B-vitamins, chelated minerals and gentle zinc (new label, same advanced formula, you may receive either label)*
- SLOW-RELEASE FORMULA: blood nutrient levels are optimized with bioactive vitamin forms & slow-release formula. Take 1 tablet twice per day as a split dose
- MULTIVITAMIN FOR MEN: 22 high-potency nutrients including bioactive B-complex, chelated minerals and antioxidant complex enhanced with lycopene; iron-free
- MORE OF WHAT YOU NEED, LESS OF WHAT YOU DON'T - our nutritionists have formulated a comprehensive multivitamin for men, topping up nutrients often lacking in everyday diets, without unnecessary extras*
- PURE & CLEAN: lab-verified ingredients; UK GMP manufactured; vegan; no silicon dioxide or magnesium stearate; fully recyclable packaging; easy-to-swallow oval tablets
$19.51
SALE
β$3.33
Igennus Methylated Women's Multivitamin, 21 Highly Bioavailable Nutrients, Clean Label & Sustained Release, Active B-Vitamins and Gentle Iron, Easy-to-Swallow, 60 Vegan Tablets, 30 Servings
- METHYLATED & ACTIVE FORMS each nutrient form has been carefully selected to optimize the journey from supplement to cell. Includes methylated B-vitamins, chelated minerals, gentle iron and zinc (new label, same advanced formula, you may receive either label)*
- PURE & CLEAN vegan, non-GMO, hypoallergenic & lab-verified ingredients with no unpleasant fillers (silicon dioxide, magnesium stearate or titanium dioxide). GMP manufactured in the UK
- HIGH POTENCY we have boosted levels of iron, B-vitamins, vitamin D and zinc in ratios that work in balance with the body. Provides enhanced support for energy, immunity, hormone balance and mood. Supplementing with iron may not be suitable for postmenopausal women*
- MORE OF WHAT YOU NEED, LESS OF WHAT YOU DON'T - our nutritionists have formulated a comprehensive multivitamin for women of menstruating age, topping up nutrients often lacking in everyday diets, without unnecessary extras*
- ALL-DAY COVERAGE this high-absorption formula is enhanced with sustained release delivery, optimizing blood nutrient levels for maximum health benefits and peace of mind. Take two, small tablets daily*
$15.62
SALE
β$3.00
Igennus Methylated Kids Multivitamin Gummy, MTHFR Supplement with B-Vitamins & Vitamin D, No Artificial Sweeteners or Flavors, Sugar Free, Age 4+, 90 Berry Gummies, Non-GMO, Halal, Clean Label
- METHYLATED MULTIVITAMIN GUMMY: higher potency than conventional gummies, this formula delivers a meaningful top-up of 11 key vitamins and minerals, including A, C, D and E, iodine, methylated B-vitamins and zinc
- ACTIVE NUTRIENT FORMS: each gummy delivers high absorption and bioactive nutrients; methylated B-vitamins, including folate (MTHFR-friendly) and methylcobalamin B12; and bioactive zinc
- PURE & CLEAN: we only use clean and hypoallergenic ingredients (no sugar, glucose syrup, artificial colors, flavors, sweeteners, or preservatives). Tested for heavy metals and lab-verified, GMP-manufactured, recyclable & BPA-free packaging, vegan
- SUGAR-FREE BERRY GUMMIES: the tasty mixed berry flavor gummies, include real fruit powder and are sugar-free and tooth-friendly. Children aged 4-8 take 1 gummy, aged 9+ take 2 gummies daily
- GROWTH, BRAIN & IMMUNE HEALTH: together, these nutrients support focus and learning, growing bodies and bones and provide immune support*
$24.95
Power By Naturals Methyl Multi One - Iron-Free Methylated Multivitamin with Quatrefolic 5-MTHF, Active B12, P5P, CoQ10 & Zinc for MTHFR Support - Energy & Focus Formula - 60 Capsules (2-Month Supply)
- EXPERIENCE THE POWER OF METHYL MULTI ONE: Our high-potency methylated multivitamin for men and women, offering a comprehensive blend of 27 vitamins and minerals, including methylated b complex, ADK, C and E in highly bioavailable forms. Packed with CoQ10, 5-MTHF, and ALA for antioxidant support, this formula is designed for easy absorption. It's your balanced, convenient, and economical one-a-day solution for adults.
- UNLOCK ESSENTIAL MTHFR SUPPORT: Our methylated multivitamin is here to elevate your mineral intake, especially if you have gene variants. With body-ready active forms like bioactive Folate, Methyl B12/B6, and enzymatic cofactors, it optimizes methylation, promoting overall well-being and balance.
- ALL -IN-ONE DAILY VEGAN MULTIVITAMIN: Get complete daily nutrition in just one capsule. Our convenient, balanced one-a-day multivitamin supports overall wellness, including bone, heart, eye, and metabolic health. Packed with ADK, methyl folate, active B12, CoQ10, and essential vitamins/minerals, including amino acids and B vitamins, it ensures your body gets everything it needs every day.
- NATURAL VARIATIONS EXPLAINED: Some bioactive vitamins may have a noticeable scent due to oxidation, and you might see product speckles from chelated minerals that aid absorptionβboth are normal occurrences. We avoid artificial additives to preserve the product's natural characteristics. Store it in a sealed, dry space at a cool room temperature or refrigerate to minimize scent due to oxidation.
- USA-MADE EXCELLENCE: Our USA-made products feature premium ingredients, crafted in a top-tier NSF/GMP facility for safety. Our multivitamin is gluten-free, GMO-free, Vegan-Friendly, and additive-free, showing our dedication to your well-being and smart nutrition choices. Experience the confidence that comes with American-made quality.
$39.95
Last update on 2025-05-24 / Affiliate links / Images from Amazon Product Advertising API