Sore throat and congestion can be incredibly uncomfortable, but finding the right medicine can provide much-needed relief. The best medicine for sore throat and congestion includes a variety of over-the-counter options such as throat lozenges, decongestants, and antihistamines that target symptoms effectively. Popular choices often feature ingredients like menthol and eucalyptus to soothe irritation, while others may contain pain relievers to reduce discomfort. Additionally, natural remedies like honey and herbal teas can complement these medications for a holistic approach to recovery.
Amazon Basic Care Tussin Severe CF Max Syrup, Multi-Symptom Cough, Cold and Flu Liquid Medicine, Non-Drowsy, Relieves Cough, Sore Throat, Body Aches, Fever, Nasal and Chest Congestion, 8 fl oz
- ACTIVE INGREDIENTS: This cold medicine contains a pain reliever/fever reducer, cough suppressant, expectorant and nasal decongestant. Compare to the active ingredients in Robitussin Severe Multi-Symptom Cough Cold + Flu.
- MAXIMUM STRENGTH: This cold medicine provides maximum strength relief of multiple cold and flu symptoms such as cough, nasal congestion, sinus congestion and pressure, minor aches and pains, sore throat, headache and temporarily reduces fever.
- MUCUS RELIEF: Take this cold medicine to help loosen phlegm (mucus) and thin bronchial secretions to drain bronchial tubes and make coughs more productive.
- NON-DROWSY: This non-drowsy cold and flu medicine provides relief for adults and children age 12 years and over. Dosage cup included.
- GREAT TASTING COLD MEDICINE: Amazon Basic Care Tussin CF Max, Multiple Symptom Cough Cold & Flu is gluten free, sugar free and alcohol free. Maximum strength claim based on maximum levels of active ingredients per 4 hour dose.
$5.01
SALE
−$3.02
VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps
- RELIEF YOU TRUST, DAY & NIGHT. Use non-drowsy DayQuil SEVERE for daytime relief and at night try NyQuil SEVERE for fast relief so you can rest.
- POWERFUL COLD & FLU RELIEF. DayQuil and NyQuil SEVERE temporarily relieve common cold & flu symptoms
- NOTHING WORKS FASTER. Just one dose starts working fast to provide effective cold & flu relief
- PROVEN RELIEF FOR YOUR WORST COLD & FLU SYMPTOMS. Life doesn’t stop when you have a cold. NyQuil and DayQuil SEVERE tackle your most bothersome cold & flu symptom
- WORLD'S #1 SELLING OTC COUGH AND COLD BRAND. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms.
$16.97
SALE
−$3.00
Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.
- 24-count of Tylenol Cold + Flu Severe Pain Reliever & Fever Reducer Medicine Caplets provide effective relief of multiple symptoms due to the flu and common cold
- This severe cold & flu medicine helps relieve fever, headache, minor aches and pains, sore throat, nasal congestion, and cough. It also helps loosen phlegm (mucus) and thin bronchial secretions to make coughs more productive.
- Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches & pains, as well as 10 mg of the cough suppressant dextromethorphan HBr to help quiet coughs
- Each caplet also contains 5 mg of the nasal decongestant phenylephrine HCl to help relieve congestion and 200 mg of the expectorant guaifenesin to help loosen phlegm (mucus) and make coughs more productive
- From the doctor-recommended pain relief brand, this cold & flu medicine is suitable for use by adults and children 12 years and older for powerful multi-symptom relief
$7.67
Contac Non-Drowsy Day & Multi-Symptom Night Cold & Flu Medicine, Maximum Strength Relief for Fever, Sore Throat, Nasal Congestion, Head & Body Aches, Runny Nose, 28 Count, 16 Day, 12 Night Caplets
- FAST-ACTING, MAXIMUM-STRENGTH RELIEF: Get 24-hour relief from common cold & flu symptoms, including nasal congestion, sinus congestion and pressure, sore throat, head & body aches and fever, runny nose, and sneezing
- NON-DROWSY, DAYTIME RELIEF: Our severe cold & flu medicine provides symptom relief without making you drowsy; Stay alert and active throughout your day
- NIGHTTIME COMFORT: Sleep better with our nighttime formula that eases symptoms for restful sleep
- 24-HOUR RELIEF: Feel better and stay alert by using our daytime formula with Phenylephrine HCI a nasal decongestant to ease congestion and acetaminophen a pain reliever/fever reducer to relieve minor aches, pains and sore throat; get some rest at night with our nighttime formula that also contains Chlorpheniramine maleate an antihistamine to ease your symptoms overnight
- FIGHT THE FLU & COLD: Contac Cold + Flu tackles severe cold & flu symptoms for adults and children 12 years and older; FSA/HSA eligible, gluten-free and no artificial colors
$8.49
SALE
−$2.52
Mucinex Fast-Max Cold and Flu & Nightshift Severe Cold and Flu Medicine for Adults, Over-the-Counter Medication Combo Pack for Sore Throat Relief, Decongestant, Cough & Cold Medicines, 2 x 6 Fl Oz
- COUGH COLD AND FLU MEDICINES FOR ADULTS: This combo pack of Maximum Strength Mucinex Fast-Max Cold & Flu and Nightshift Severe Cold & Flu provides powerful multi-symptom cold and flu relief for your worst cold and flu symptoms
- SORE THROAT RELIEF: Both liquids contain Acetaminophen, which helps reduce fever and relieves sore throat, headache, and body pain
- COUGH MEDICINE FOR ADULTS: Both liquids contain Dextromethorphan HBr, which helps suppress and quiet cough
- CHEST CONGESTION RELIEF: Daytime liquid contains Guaifenesin, an expectorant, which helps relieve chest congestion and thins and loosens mucus
- NASAL DECONGESTANT: Both liquids contain Phenylephrine HCl, a nasal decongestant, which helps relieve stuffy nose, sinus pressure, & nasal congestion
$19.97
SALE
−$1.19
Boiron ColdCalm Tablets for Relief of Common Cold Symptoms Such as Sneezing, Runny Nose, Sore Throat, and Nasal Congestion - Non-Drowsy - 60 Count
- MULTI-SYMPTOM COLD RELIEF: ColdCalm Tablets relieve common cold symptoms, including sneezing, runny nose, nasal congestion, and minor sore throat, at every stage of the cold.* Non-drowsy relief with no known drug interactions for ages 4 and up.
- MELTAWAY CONVENIENCE: ColdCalm Tablets dissolve easily in the mouth without the need for water, chewing or swallowing, so you can act fast against cold symptoms anywhere, anytime.
- HELP YOUR BODY THE NATURAL WAY: This homeopathic cold medicine is non-drowsy and non-habit forming and can be taken day or night. It’s also gluten-free and contains no artificial sweeteners, flavors, colors, or preservatives.
- A TRUSTED BRAND: With more than 90 years of expertise, Boiron medicines are manufactured to meet the highest standards of cGMP and HPUS for purity and quality.
- BUY WITH YOUR HSA/FSA: Many of your favorite Boiron medicines are now eligible for reimbursement. Look for our logo designating products that can be paid for with your Health Savings Account or Flexible Savings Account.
$9.99
SALE
−$0.92
Tylenol Cold + Head Congestion Severe Medicine Caplets for Fever, Pain, and Congestion, Acetaminophen Pain Reliever, Fever Reducer, 24 Count
- 24-count bottle of Tylenol Cold Head Congestion Severe Caplets provide effective relief of multiple symptoms due to the flu and common cold
- This severe cold & flu medicine helps relieve headache, minor aches and pains, sore throat, nasal congestion, and sinus congestion and pressure. It also temporarily reduces fever and helps to loosen phlegm to make coughs more productive.
- Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches and pains, as well as 5 mg of the nasal decongestant phenylephrine HCl to help relieve congestion
- Each caplet also contains 200 mg of the expectorant guaifenesin to help loosen phlegm (mucus). Tylenol Cold Head Congestion Severe Caplets do not contain dextromethorphan HBr.
- From the #1 doctor-recommended pain relief brand, this cold & flu medicine is suitable for use by adults and children 12 years and older for powerful multi-symptom relief
$7.57
SALE
−$2.52
Alka-Seltzer Plus Severe, Cold & Flu Medicine, Citrus Effervescent Tablets, Nasal & Sinus Congestion, Sneezing, Runny Nose, Cough, Sore Throat 24 Count, Packaging May Vary
- Our fantastic formula made even better: improved flavor, less sodium, & aspartame free
- Our severe Cold & Flu medicine formula provides unbeatably liquid fast relief of headache, sore throat, cough, nasal & sinus congestion, runny nose, sneezing, aches & pains and fever.
- Quickly dissolves in water and instantly ready to start working so you can get back to your busy life.
- Each box containing 10 Sachets each containing 1 individually wrapped dose (2 effervescent tablets), which makes it easy to take with you on the go
- Comes in Effervescent form, in a refreshing Citrus flavor. Use as directed.
$9.47
Amazon Basic Care Severe Daytime Cold & Flu, Maximum Strength Liquid Medicine, Relieves Aches, Pain, Fever, Cough, Nasal & Chest Congestion, Sore Throat, Original Flavor, 8 fl oz (Pack of 1)
- ACTIVE INGREDIENTS: Compare to the active ingredients in Vicks DayQuil Severe Cold and Flu: acetaminophen, dextromethorphan HBr, guaifenesin, and phenylephrine HCl
- MAXIMUM STRENGTH: Amazon Basic Care Severe Daytime Cold and Flu Relief provides maximum strength relief of headache, fever, sore throat, minor aches and pains, nasal and sinus congestion, sinus pressure, cough and chest congestion
- NON-DROWSY DAYTIME RELIEF: This non-drowsy daytime medicine provides powerful relief of severe symptoms so you can take on the day; alcohol and antihistamine free
- EFFECTIVE: Each dose combines a pain reliever/fever reducer, cough suppressant, expectorant and nasal decongestant to soothe your severe daytime symptoms
- POWERFUL LIQUID: This liquid medicine in original flavor provides powerful, multi-symptom relief; for adults and children age 6 and over; gluten, alcohol and antihistamine free
$5.76
SALE
−$2.35
Boiron Chestal Honey Adult Cold and Cough Syrup for Nasal and Chest Congestion, Runny Nose, and Sore Throat Relief - 6.7 Fl oz
- RELIEF FOR COUGH & CHEST CONGESTION: Chestal Honey is made with a blend of homeopathic active ingredients and 100% premium Acacia honey to that work to relieve all types of common coughs and loosen chest congestion.*
- DAY & NIGHT RELIEF: Chestal Honey is your day and night solution, calming those dry, fitful coughs at bedtime, so they don't prevent sleep, but without drowsy side effects for the day.
- FOR THE WHOLE FAMILY: Recommended for everyone ages 2 and up, Chestal Honey is available for both adults and children in 6.7 fl oz bottles.
- HELP YOUR BODY THE NATURAL WAY: Homeopathic medicine uses highly diluted biological, botanical, or mineral substances to relieve symptoms. Our cough syrups work with your body without the risk of contraindications, or known drug interactions.
- A BETTER WAY: At Boiron, we believe there's a better way to feel better. Since 1932, the Boiron family has been dedicated to providing the purest medicines using sustainable practices. As world leader in homeopathic medicines, quality has always been our passion and you well-being is our goal.
$9.53
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API