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10 Best medicine for sinus headache and pressure (2025) - Joe's Italian Restaurant & Pizza

10 Best medicine for sinus headache and pressure (2025)

Sinus headache and pressure can be incredibly uncomfortable, but there are effective medicines available to alleviate these symptoms. Over-the-counter options like decongestants, antihistamines, and pain relievers can provide significant relief. Additionally, nasal sprays and steam inhalation can help reduce inflammation and clear nasal passages. For those seeking targeted treatments, prescription medications may also be an option. It's essential to consult with a healthcare professional to determine the best course of action for your specific needs.

SALE −$1.88

Tylenol Sinus + Headache Daytime Non-Drowsy Relief Caplets, Acetaminophen 325mg, Nasal Decongestant for Sinus Pressure, Headache & Nasal Congestion Relief, 24 ct

  • 24-count box of Tylenol Sinus + Headache Daytime Caplets for non-drowsy sinus symptom and headache pain relief due to the common cold, hay fever or other respiratory allergies
  • Pain reliever and nasal decongestant formulated to temporarily reduce fever and relieve symptoms of nasal congestion, sinus headache and pressure
  • Each sinus relief caplet contains 325 milligrams of acetaminophen to temporarily relieve pain and reduce fever as well as 5 milligrams of phenylephrine HCl, a nasal decongestant to help clear nasal passages
  • The non-drowsy formula of this sinus medicine provides effective daytime symptom relief by promoting sinus drainage and helping to decongest sinus openings and passages
  • From the #1 doctor recommended pain relief brand, these daytime headache and sinus relief caplets are suitable for adults and children ages 12 years and older for powerful daytime cold symptom relief

$8.79

Vicks Sinex SEVERE LiquiCaps, All-In-One Sinus Relief, Non-Drowsy, Nasal Decongestant, Maximum Strength Relief of Sinus Headache, Pain, Pressure, & Congestion, 24 LiquiCaps

  • Experience fast, powerful relief from nasal congestion, sinus pressure, sinus headache, and sinus pain!
  • Best suited to treat sinus symptoms caused by the common cold, hay fever, or other upper respiratory allergies because it reduces pressure in the sinuses and relieves sinus pain!
  • The powerful, non-drowsy nasal decongestant medicine and pain reliever help to provide all in one relief for your sinus symptoms!
  • HSA and FSA eligible, Check with your provider for more details
  • This product is not formulated with an antihistimine allergy medicine and is not intended to treat runny nose, itchy & watery eyes, or sneezing

$9.25
SALE −$2.29

Sudafed PE Sinus Pressure + Pain Relief Tablets, Maximum Strength, Non-Drowsy, OTC Sinus Relief Medicine with Acetaminophen Pain Reliever & Phenylephrine HCl Nasal Decongestant, 24 ct

  • DECONGESTANT & PAIN RELIEF: 24-count package of Sudafed PE Sinus Pressure and Pain maximum strength non-drowsy decongestant tablets for fast and powerful relief of sinus congestion, sinus pressure, and nasal congestion
  • NON-DROWSY COLD & SINUS MEDICINE: Sudafed sinus and pain medication helps to temporarily relieve nasal congestion associated with hay fever, upper respiratory allergies and the common cold, plus, helps relieve sinus pressure and sinus headaches
  • PHENYLEPHRINE & ACETAMINOPHEN: Each sinus congestion and pressure relief tablet contains 5 mg of phenylephrine HCI, a nasal decongestant that provides non-drowsy relief, plus, 325 mg of acetaminophen, a pain and fever reducer
  • HOW TO USE: Sudafed PE sinus pressure and pain relief congestion relief tablets can be used by adults and children ages 12 and up. Take two tablets every four hours; do not exceed 10 tablets within a 24 hour time period
  • FSA HSA APPROVED PRODUCT: Sinus congestion relief and pain medicine from Sudafed, the #1 pharmacist recommended brand among oral OTC decongestants. Sudafed PE Sinus Pressure + Pain is HSA & FSA eligible. Product eligibility may vary by plan
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$8.38
SALE −$0.50

Boiron SinusCalm Tablets for Sinus Pain Relief, Runny Nose, Congestion, Sinus Pressure, Headache - 60 Count

  • Targets sinus pain with a stuffy or runny nose.
  • Non-drowsy and won't mask symptoms of a more serious condition
  • Homeopathic multi-symptom sinus Relief medicine, non-habit forming and no risk of a rebound effect
  • Slightly sweet pellets melt under the tongue without water, chewing, or swallowing pills. Pellets can also be dissolved in water for children or seniors. Recommended for everyone ages 6 and up.
  • Available over the counter in a box of two multidose tubes for home or on the go (approximately 80 oral pellets per tube)

$10.49

Vicks Sinex SEVERE, All-In-One Sinus + Mucus Relief, Non-Drowsy, Loosens Mucus, Maximum Strength Relief of Pain, Pressure, Congestion, & Headache Relief, 24 LiquiCaps

  • Experience fast, powerful relief from nasal congestion, sinus pressure, sinus headache, sinus pain, chest congestion and mucus!
  • Best suited to treat sinus symptoms caused by the common cold, hay fever, or other upper respiratory allergies because it thins and loosens mucus, reduces pressure in the sinuses, and relieves sinus pain!
  • The powerful, non-drowsy nasal decongestant medicine, expectorant, and pain reliever help to provide all in one relief for your sinus symptoms!
  • HSA and FSA eligible, Check with your provider for more details
  • This product is not formulated with an antihistimine allergy medicine and is not intended to treat runny nose, itchy & watery eyes, or sneezing

$8.84
SALE −$3.74

Boiron SinusCalm Pellets for Sinus Pain Relief, Runny Nose, Congestion, Sinus Pressure, Headache - 2 Count (160 pellets)

  • SinusCalm pellets relieves nasal congestion, sinus pain and pressure, and headache due to the common cold or allergies.
  • The non-drowsy, melt-away pellets are phenylephrine-free and won’t interact with other medications. Free from preservatives and artificial colors & flavors.
  • Portable tubes are great for on the go relief!
  • Slightly sweet pellets melt under the tongue without water, chewing, or swallowing pills. Recommended for everyone ages 6 and up.
  • Two multidose tubes for home or on the go (approximately 80 oral pellets per tube)
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$11.65
SALE −$2.20

Sudafed PE Head Congestion + Mucus Tablets for Sinus Pressure, Pain & Congestion, 24 ct

  • 24-count box of Sudafed PE Head Congestion + Mucus Tablets to provide non-drowsy relief from sinus pain and pressure, nasal & chest congestion, and excess mucus
  • Sinus relief medicine contains 5 mg of phenylephrine HCl, a decongestant, for congestion relief and 325 mg of acetaminophen for pain and fever reduction. Also has 200 mg of guaifenesin, an expectorant, for mucus reduction
  • Head congestion tablets temporary relieves symptoms associated with hay fever, upper respiratory allergies, and the common cold
  • Non-drowsy decongestant tablets provide relief of sinus pressure, headaches, nasal and chest congestion, excess mucus, and minor aches and pains
  • Head congestion relief medicine also helps loosen mucus to clear bronchial passageways and make coughs more productive. Get powerful head congestion relief from the pharmacist recommended brand among oral OTC decongestants.

$8.47

Rite Aid Sinus Pressure and Pain Reliever PE, Non-Drowsy - 24 Tablets | Sinus Relief | Pain Relief | Nasal Decongestant | Cold Medicine for Adults | Allergy Medication | Allergy Relief | Mucus Relief

  • MAXIMUM STRENGTH: Rite Aid Maximum Strength Sinus Pressure & Pain Relief cold medicine for adults temporarily relieves minor aches and pains, nasal congestion, headache, sinus congestion and pressure, promotes sinus drainage, and temporarily reduces fever.
  • MULTI-SYMPTOM RELIEF: Rite Aid Sinus Pressure & Pain Relief relieves symptoms associated with hay fever or other respiratory allergies, and the common cold. Compare Rite Aid Daytime to the active ingredients in the leading national brand.
  • DAYTIME NON-DROWSY FORMULA: With Rite Aid allergy and cold medicine for adults, you’ll feel relief from symptoms associated with hay fever or other respiratory allergies, and the common cold— formulated without ingredients that may cause drowsiness.
  • FEVER, PAIN RELIEVER + NASAL DECONGESTANT: The Acetaminophen 325 mg & Phenylephrine HCI 5 mg in each caplet temporally relieves minor aches and pains, headache, sore throat, and fever. While the nasal decongestant reduces sinus congestion and pressure.
  • TRUSTED BRAND SINCE 1962: We hope you continue to choose Rite Aid first for your everyday health and wellness needs. Our mission is to improve the health and wellness of our communities and provide our customers with the best products, services, and advice.
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SALE −$4.00

Moist Heat Sinus Pressure Relief Mask with 3 Heat Settings, Extra Large Face Heating Pad for Eyes, Sinusitis, Hormone Migraine, Tension Headache Relief Black

  • EXTRA LARGE HEAT ELEMENTS FOR PAIN RELIEF: the heating pad specific design for face features the full coverage heat for forehead, sinus and cheek, covering the major pain and sore of head, such as tension headache, sinusitis, Menstrual migraine, puffy eyes and other head issues.
  • FAST AND LASTING HEAT: It will begin to heat in several seconds after plugged in and rise to target temperature in 3-5 minutes, providing fast and effective heat therapy for pain areas. Compared to those microwavable sinus mask, you don’ t need to get up and down to put it in the microwave to keep warm, all you need to do is plugging it in and enjoying the continuous heat therapy.
  • CUSTOMIZED TEMPERATURE AND TIMER SETTINGS: Sinus Relief mask is equipped with Easy-to-Use LED Display hand Controller, There are three temperature and five timer settings available, customized designs for your best fitting temperature and auto-off timer for warming or heat therapy. But NEVER SLEEP when wearing the sinus relief mask even if you have set the auto-off timer.
  • DEEP SOOTH WITH MOIST HEAT: This extra-large mask can be used for dry heat therapy or moist heat therapy. For moist heat, simply use the provided spray bottle to apply a fine mist to the inner side of the heated eye mask. Moist heat warms the tissues more quickly because water transfers heat faster than air. The fast heat helps moisture deeper into the tissue beneath, increasing circulation to problem areas, bringing in new blood cells while taking away wastes to speed up recovery.
  • SAFE FOR DAILY USE: Mask is powered by provided 12V adapter which is safe voltage for human beings and LED Display hand Controller with total 9.5 ft Extra Long power cord (NOT FOR PORTABLE USE). Our Heating pad choose fiber Heating Element and embedded with thermostat sensor, which is more durable and safer than regular 110V heating pad.

$35.99

Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API