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10 Best medicine for head congestion (2025) - Joe's Italian Restaurant & Pizza

10 Best medicine for head congestion (2025)

Head congestion can be a frustrating symptom, often caused by allergies, colds, or sinus infections. The best medicine for head congestion includes a variety of over-the-counter options that can help alleviate discomfort and promote easier breathing. From decongestants to antihistamines, these medications work to reduce swelling in the nasal passages and clear mucus buildup. It's essential to choose the right product based on your specific symptoms and consult with a healthcare professional if needed.

SALE −$2.20

Sudafed PE Head Congestion + Mucus Tablets for Sinus Pressure, Pain & Congestion, 24 ct

  • 24-count box of Sudafed PE Head Congestion + Mucus Tablets to provide non-drowsy relief from sinus pain and pressure, nasal & chest congestion, and excess mucus
  • Sinus relief medicine contains 5 mg of phenylephrine HCl, a decongestant, for congestion relief and 325 mg of acetaminophen for pain and fever reduction. Also has 200 mg of guaifenesin, an expectorant, for mucus reduction
  • Head congestion tablets temporary relieves symptoms associated with hay fever, upper respiratory allergies, and the common cold
  • Non-drowsy decongestant tablets provide relief of sinus pressure, headaches, nasal and chest congestion, excess mucus, and minor aches and pains
  • Head congestion relief medicine also helps loosen mucus to clear bronchial passageways and make coughs more productive. Get powerful head congestion relief from the pharmacist recommended brand among oral OTC decongestants.

$8.47
SALE −$0.92

Tylenol Cold + Head Congestion Severe Medicine Caplets for Fever, Pain, and Congestion, Acetaminophen Pain Reliever, Fever Reducer, 24 Count

  • 24-count bottle of Tylenol Cold Head Congestion Severe Caplets provide effective relief of multiple symptoms due to the flu and common cold
  • This severe cold & flu medicine helps relieve headache, minor aches and pains, sore throat, nasal congestion, and sinus congestion and pressure. It also temporarily reduces fever and helps to loosen phlegm to make coughs more productive.
  • Each caplet contains 325 mg of acetaminophen to help reduce fever and relieve minor aches and pains, as well as 5 mg of the nasal decongestant phenylephrine HCl to help relieve congestion
  • Each caplet also contains 200 mg of the expectorant guaifenesin to help loosen phlegm (mucus). Tylenol Cold Head Congestion Severe Caplets do not contain dextromethorphan HBr.
  • From the #1 doctor-recommended pain relief brand, this cold & flu medicine is suitable for use by adults and children 12 years and older for powerful multi-symptom relief

$7.57
SALE −$1.88

Tylenol Sinus + Headache Daytime Non-Drowsy Relief Caplets, Acetaminophen 325mg, Nasal Decongestant for Sinus Pressure, Headache & Nasal Congestion Relief, 24 ct

  • 24-count box of Tylenol Sinus + Headache Daytime Caplets for non-drowsy sinus symptom and headache pain relief due to the common cold, hay fever or other respiratory allergies
  • Pain reliever and nasal decongestant formulated to temporarily reduce fever and relieve symptoms of nasal congestion, sinus headache and pressure
  • Each sinus relief caplet contains 325 milligrams of acetaminophen to temporarily relieve pain and reduce fever as well as 5 milligrams of phenylephrine HCl, a nasal decongestant to help clear nasal passages
  • The non-drowsy formula of this sinus medicine provides effective daytime symptom relief by promoting sinus drainage and helping to decongest sinus openings and passages
  • From the #1 doctor recommended pain relief brand, these daytime headache and sinus relief caplets are suitable for adults and children ages 12 years and older for powerful daytime cold symptom relief
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$8.79
SALE −$3.02

Mucinex Sinus Max Severe Congestion & Pain Relief, Maximum Strength Nasal & Sinus Relief, Decongestant for Adults, Acetaminophen Pain Reliever, Guaifenesin Expectorant and Mucus Removal, 20 Caplets

  • MAXIMUM STRENGTH RELIEF: Maximum Strength Mucinex Sinus-Max Severe Congestion & Pain helps relieve pain, headache, nasal congestion, sinus congestion and chest congestion.
  • #1 TRUSTED COLD AND COUGH BRAND: #1 Cold and Cough brand doctors trust*
  • PAIN RELIEVER: Contains Acetaminophen which relieves minor aches and pains
  • EXPECTORANT: Contains Guaifenesin that thins and loosens mucus; relieves chest congestion
  • NASAL DECONGESTANT: Contains Phenylephrine HCl that provides relief for nasal congestion, sinus congestion and pressure

$10.97
SALE −$2.70

Advil Sinus Congestion and Pain, Sinus Relief Medicine, Pain Reliever and Fever Reducer with Ibuprofen and Phenylephrine HCl - 10 Coated Tablets

  • One package of 10 coated tablets of Advil Sinus Congestion and Pain, Sinus Relief Medicine, Pain Reliever and Fever Reducer with Ibuprofen and Phenylephrine HCl
  • Advil ibuprofen 200mg pain medicine for adults temporarily relieves fever, minor body aches and headache
  • Phenylephrine HCl 10 mg tablets provide sinus pressure relief, nasal congestion relief and nasal swelling relief
  • Coated tablets are easily portable, so you can have Advil congestion relief ready whenever you need it
  • Sinus congestion medicine for adults and children 12 years and older - the perfect addition to your college dorm room essentials

$3.79
SALE −$2.65

Sudafed PE Sinus Congestion Day + Night Maximum Strength Decongestant & Antihistamine Tablets with Phenylephrine HCl & Diphenhydramine HCl, Helps Nasal & Sinus Pressure & Congestion, 20 ct

  • 20-count of Sudafed PE Sinus Congestion Day + Night Maximum Strength Decongestant Medicine Tablets to temporarily relieve sinus pressure and sinus congestion for both day and night
  • Each multi-pack contains 20 tablets of nasal decongestant, with 12 Daytime and 8 Nighttime tablets for powerful symptom relief throughout the day and while you sleep
  • Each daytime and nighttime dose contains 10 milligrams of the nasal decongestant phenylephrine HCl per tablet and each nighttime dose also contains 25 milligrams per tablet of the antihistamine diphenhydramine HCl
  • Both formulas help relieve sinus pressure and sinus congestion, and nasal congestion due to the common cold, hay fever, or upper respiratory allergies. Nighttime tablets also relieve sneezing, runny nose, itchy, watery eyes and itchy throat or nose
  • From the #1 pharmacist recommended brand among oral OTC decongestants, this maximum-strength formula can be used by adults and children 12 years and older for powerful symptom relief
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$8.02
SALE −$2.69

Sudafed PE Head Congestion + Flu Severe Decongestant Tablets for Adults, 24 ct

  • Sudafed PE Head Congestion + Flu Severe Tablets help provide pain, cold and flu symptom relief, and can be used by adults and children who are 12 years and older.
  • Each non-drowsy decongestant caplet contains 325 mg of acetaminophen, a pain reliever and f ever reducer, as well as 5 mg of phenylephrine HCl to help relieve nasal congestion
  • This cold & flu medicine for adults also contains 100 mg of guaifenesin, an expectorant, and 10 mg of dextromethorphan HBr, a cough suppressant
  • Temporarily relieves some of the toughest cold symptoms, such as coughing, nasal congestion, chest congestion, sore throat, headache, and minor aches and pains
  • This non-drowsy relief formula helps loosen phlegm (mucus) to drain bronchial tubes and make coughs more productive. Get powerful head congestion relief from the pharmacist recommended brand among oral OTC decongestants.

$7.98

Afrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)

  • Ridiculously Fast Relief: Unblock your nose in seconds with Afrin No Drip Severe Congestion Nasal Mist, a fast-acting nasal pump mist decongestant providing sinus pressure and congestion relief with cooling menthol in a convenient twin pack
  • Effective for Severe Congestion: This maximum strength nasal spray is perfect for relieving severe nasal congestion and sinus pressure caused by colds and allergies, offering quick and effective stuffy nose relief for adults and children 6 years and older
  • No Drip Technology: Afrin's No Drip technology ensures the medicated mist stays where it's sprayed, providing effective nasal decongestion without the mess or discomfort of it dripping from your nose or down your throat
  • Cooling Menthol Formula: Experience the soothing and cooling sensation of menthol while the powerful decongestant works to constrict blood vessels in the nasal passages and reduce swelling to help you breathe easier
  • 12-Hour Non-Drowsy Decongestion: Experience long-lasting relief for up to 12 hours without drowsiness, perfect for both day and night use to alleviate nasal congestion and provide sinus pressure relief
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$16.46

Contac Non-Drowsy Day & Multi-Symptom Night Cold & Flu Medicine, Maximum Strength Relief for Fever, Sore Throat, Nasal Congestion, Head & Body Aches, Runny Nose, 28 Count, 16 Day, 12 Night Caplets

  • FAST-ACTING, MAXIMUM-STRENGTH RELIEF: Get 24-hour relief from common cold & flu symptoms, including nasal congestion, sinus congestion and pressure, sore throat, head & body aches and fever, runny nose, and sneezing
  • NON-DROWSY, DAYTIME RELIEF: Our severe cold & flu medicine provides symptom relief without making you drowsy; Stay alert and active throughout your day
  • NIGHTTIME COMFORT: Sleep better with our nighttime formula that eases symptoms for restful sleep
  • 24-HOUR RELIEF: Feel better and stay alert by using our daytime formula with Phenylephrine HCI a nasal decongestant to ease congestion and acetaminophen a pain reliever/fever reducer to relieve minor aches, pains and sore throat; get some rest at night with our nighttime formula that also contains Chlorpheniramine maleate an antihistamine to ease your symptoms overnight
  • FIGHT THE FLU & COLD: Contac Cold + Flu tackles severe cold & flu symptoms for adults and children 12 years and older; FSA/HSA eligible, gluten-free and no artificial colors

$8.49

Vicks Sinex SEVERE, All-In-One Sinus + Mucus Relief, Non-Drowsy, Loosens Mucus, Maximum Strength Relief of Pain, Pressure, Congestion, & Headache Relief, 24 LiquiCaps

  • Experience fast, powerful relief from nasal congestion, sinus pressure, sinus headache, sinus pain, chest congestion and mucus!
  • Best suited to treat sinus symptoms caused by the common cold, hay fever, or other upper respiratory allergies because it thins and loosens mucus, reduces pressure in the sinuses, and relieves sinus pain!
  • The powerful, non-drowsy nasal decongestant medicine, expectorant, and pain reliever help to provide all in one relief for your sinus symptoms!
  • HSA and FSA eligible, Check with your provider for more details
  • This product is not formulated with an antihistimine allergy medicine and is not intended to treat runny nose, itchy & watery eyes, or sneezing

$8.84

Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API