Laundry detergent for stains is essential for maintaining the cleanliness and freshness of your clothes. In 2025, the market offers a variety of top-performing detergents specifically designed to tackle tough stains, ensuring your garments look their best. From powerful enzymatic formulas to eco-friendly options, these detergents cater to different needs and preferences, making it easier than ever to find the perfect solution for your laundry challenges. Whether you're dealing with grass, grease, or wine stains, the right detergent can make all the difference in restoring your fabrics to their original glory.
SALE
−$2.01
ARM & HAMMER Deep Clean Stain Formula, Liquid Laundry Detergent, 102 fl oz, 68 Loads
- One 102 fl oz bottle of ARM & HAMMER Deep Clean Stain Formula Sparkling Clean Laundry Detergent
- Liquid laundry detergent features pH Power Technology with millions of micro-scrubbers that surround and strip away stain and dirt particles for soaked-through clothes
- This laundry detergent penetrates between fibers where stains and dirt linger to deeply clean clothes
- Laundry stain remover with a sparkling clean scent leaves your clothes clean and fresh
- Works in all machines and at all wash temperatures as an effective clothes stain remover
$11.98
SALE
−$2.01
Arm & Hammer Plus OxiClean Fresh Scent, 128 Loads Liquid Laundry Detergent, 166.5 Fl oz
- One 166.5 fl oz bottle of ARM & HAMMER Plus OxiClean Stain Remover Fresh Scent Liquid Laundry Detergent cleans 128 medium loads when used as directed
- HE detergent that delivers 5 powerful cleaning benefits in 1: it attacks stains, fights odors, whitens whites, brightens colors and delivers a boost of freshness
- With trusted ARM & HAMMER Baking Soda plus OxiClean stain fighters, this HE laundry detergent is formulated to deeply clean clothes and deliver lasting freshness
- Laundry stain remover forces out stubborn stains and nasty odors using OxiClean Stain Fighters to remove over 101 stains, like food, grass, grease and more
- Clean-rinsing, low-sudsing formula won’t block HE machine sensors, making it an effective choice for both standard and HE washers
$13.98
SALE
−$2.21
OxiClean Odor Blasters Versatile Odor and Stain Remover Powder, 5 lb
- One 5 lb box of OxiClean Odor Blasters Versatile Odor Eliminator and Stain Remover Powder to get out tough stains and stubborn smells
- Oxygen-based, water-activated laundry booster gets out tough dirt, persistent spots and set-in stains, plus eliminates sweat, musty towel and body odors
- Works with regular detergent as a laundry stain remover and odor neutralizer to get clothes extra clean. For best results, use as a presoak before washing
- This laundry odor remover and stain remover powder can be used as a kitchen cleaner, bathroom cleaner, and fabric odor eliminator for machine-washable fabrics, so you are ready for any mess
- Tough on stains yet gentle on fabric, this chlorine-free, color-safe stain cleaner formula removes odors and stains to help keep the clothes you love look newer, longer
$11.78
SALE
−$1.69
Nature’s Miracle Laundry Boost In-Wash Stain and Odor Remover, 32 Oz, Laundry Stain and Odor Removing Additive For All Machines
- LAUNDRY BIO-ENZYMATIC FORMULA: Helps break down and destroy tough pet stains and odors, such as urine, feces, vomit, blood, grass and drool.
- GENTLE ON FABRICS: Perfect for use on clothing, pet beds and more—not for use on specialty fabrics, including washable silk, khaki, fluorescents, wool, suede and leathers.
- SAFE FOR PETS AND HOME: Formulated without phosphates, parabens, sulfates and bleach, this product is safe for use around pets and home, when used as directed.
- ODORCAPTURE 360 TECHNOLOGY: An odor neutralizing system from Nature’s Miracle, the brand you trust because it works!
- WORKS IN ALL MACHINES INCLUDING HE: Use in addition to your laundry detergent to help loosen and remove tough pet stains and odors.
$9.30
SALE
−$1.71
Tide Ultra Oxi Boost Liquid Laundry Detergent, 84 fl oz, 59 Loads, Advanced Stain Remover, Laundry Detergent Liquid with Extra Oxi Power (Packaging May Vary)
- STAIN REMOVAL: Tide Ultra OXI Liquid Laundry Detergent helps remove stains with built-in pre-treaters
- CONCENTRATED FORMULA: Tide Ultra OXI Liquid Laundry Detergent is a concentrated formula with more cleaning agents and less water in every drop compared to our previous formula
- ODOR REMOVAL: Tide Ultra OXI Liquid Laundry Detergent helps remove odors left in clothes and active wear
- TRUSTED BRAND: Tide Ultra OXI Liquid Laundry Detergent is from America's trusted detergent brand
- HIGH EFFICIENCY COMPATIBLE: Tide Ultra OXI Liquid Laundry Detergent is compatible with both top load and front load High Efficiency (HE) machines
$12.97
SALE
−$0.51
ARM & HAMMER Plus OxiClean with Odor Blasters Concentrated Laundry Detergent, 5-in-1 Laundry Stain Remover, Fresh Burst Detergent Power Paks, 42 Count Bag
- One 42-count bag of ARM & HAMMER Plus OxiClean Pre-Measured Concentrated Laundry Detergent Power Paks, 5-in-1 laundry stain remover for deep cleaning and lasting freshness in small, easy-to-use laundry pacs
- Each pre-measured fresh scent detergent pak has 5-in-1 power as a stain remover that gets rid of 100+ stains, a deep cleaner that fights odors, a detergent that whitens and brightens, and a boost of freshness that gives laundry a clean scent
- With the deodorizing power of ARM & HAMMER Baking Soda plus Odor Blasters, this HE laundry detergent is formulated to deeply clean and deliver freshness
- Laundry stain remover forces out dirt using OxiClean Stain Fighters to remove 100+ stubborn stains like everyday food spills, grass, grease and more in combination with Odor Blaster to get rid of tough smells like wet dog, body odor, gym clothes and more
- Enjoy no measuring, no spills and no mess with these convenient laundry pacs that combine concentrated detergent with OxiClean; use two drop-and-go Power Paks for large or heavily soiled loads, one for regular or lightly soiled loads for a deep clean
$9.48
Tide PODS Laundry Detergent Pacs, 3-in-1 Stain Remover, Odor Fighter, Color Protector, 112 Count, HE compatible, Original Scent
- DEEP CLEAN IN 1 WASH: Upgrade to Tide PODS for effortless, powerful results in one step. Tide PODS laundry detergent cleans tough stains + odors in just 1 wash
- 3-IN-1 LAUNDRY SOAP: Tide PODS are pre-measured, concentrated laundry detergent pacs with built-in stain removers, odor fighters, and color protectors
- FIGHTS ODORS: Tide PODS laundry soap cleans deep and fights odors, with long-lasting Tide Spring Meadow freshness to keep your household’s laundry smelling great
- DISSOLVES QUICKLY, EVEN IN COLD: Tide PODS laundry soap dissolves quickly and activates deeply on stains, even in cold wash
- 3X CLEANING POWER: Tide PODS laundry detergent is super concentrated with 3X cleaning ingredients per dose compared to the leading bargain liquid detergent
$27.48
OxiClean Versatile Stain Remover Powder, 7.22 lb
- One 7.22 lb container of OxiClean Versatile Stain Remover Powder with over 101 uses for laundry and around the home
- Oxygen-powered, water-activated OxiClean powder removes everyday dirt and grime, and tough set-in stains from machine-washable t-shirts, sheets, towels, shoes, hats, workout gear, and kids’ and baby clothes
- Use as a stain removal presoak and as an in-wash laundry booster stain remover, with regular laundry detergent, following label directions, to get clothes extra clean
- Not just for laundry, mix with water following label directions to make a cleaning solution, to use as a kitchen cleaner, bathroom cleaner, furniture cleaner and floor cleaner for nearly any hard or soft surface in your home
- This color-safe, chlorine-free, septic tank-safe stain remover powder fights tough stains and everyday messes but is gentle on white, colored and dark fabrics
$14.98
Persil Intense Fresh Everyday Clean, Liquid Laundry Detergent, High Efficiency (HE), Deep Stain Removal, 2X Concentrated, 82.5 fl oz, 110 Loads
- With powerful Persil liquid laundry detergent, get a premium deep clean with every wash
- Remove odors, add freshness with Persil Intense Fresh scent laundry detergent. Provides long-lasting freshness without being overwhelming or perfumy.
- Persil Intense Fresh laundry detergent has fabric care ingredients to help prevent color fading
- Persil laundry detergent protects fabrics, deep cleans, and helps keep clothes looking newer, longer* *vs leading value detergent
- This 2X concentrated formula delivers more cleaning power in every drop vs our standard detergent so you don’t have to use as much to get a premium deep clean.
$25.36
Tide Liquid Laundry Detergent, Hygienic Clean Heavy Duty, Original Scent, 24 Loads, 34 fl oz
- Innovative liquid detergent technology gets between the fibers to clean hidden dirt
- Designed with 10 concentrated cleaning actives to remove visible and invisible
- Provides a deep, hygienic clean even in case of tough stains
- Works in all machines and water conditions
- Try Tide Power PODS for 50% more cleaning power vs. Tide Original Liquid
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Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API