Heartburn relief is essential for those who experience the discomfort of acid reflux. In 2025, numerous effective options have emerged to help alleviate this common issue. From over-the-counter medications to natural remedies, individuals can find a variety of solutions tailored to their needs. Whether you prefer antacids, H2 blockers, or lifestyle changes, the best heartburn relief products can significantly improve your quality of life. Explore the top choices available to discover what works best for you.
HealthCareAisle Omeprazole 20 mg, 42 Delayed-Release Capsules - Acid Reducer, Treats Frequent Heartburn, 42 Count (Pack of 1)
- EFFECTIVE HEARTBURN RELIEF: Omeprazole acid reducer capsule that treats frequent heartburn occurring 2 or more days a week.
- 14-DAY ACID REFLUX MEDICINE:Take one Omeprazole capsule daily for heartburn relief up to 24 hours. May take 1-4 days for full effect. See package label for warnings and other important information.
- COMPARABLE TO THE NATIONAL BRAND: Has the same active ingredient as Prilosec OTC*
- STOP HEARTBURN AT THE SOURCE: Our Omeprazole 20mg capsules inbibit the proton pumps in the stomach from producing excess acid, acting as an acid reducer.
- Directions: use as directed for 14 days; do not take for more than 14 days or more often than every 4 months unless directed by your healthcare provider
$11.21
SALE
−$4.96
Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg, Treats Frequent Heartburn, Acid Reducer, Heartburn Medicine, 42 Count (Pack of 1) (Packaging may vary)
- ACTIVE INGREDIENT: The active ingredient in these delayed release tablets is omeprazole 20 mg, which works as an acid reducer to treat frequent heartburn. Compare to Prilosec OTC
- TREATS FREQUENT HEARTBURN: Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg treat frequent heartburn that occurs 2 or more times a week
- ACID REDUCER: Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg is a Proton Pump Inhibitor (PPI) that deactivates pumps in the stomach lining to inhibit acid production at the source.
- 14-DAY COURSE OF HEARTBURN TREATMENT: Taken once every 24 hours for 14 days, Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg is not intended for immediate relief of heartburn and may take 1 to 4 days for full effect.
- HEARTBURN TIPS: Do not eat late at night or just before bedtime. Certain foods or drinks are more likely to cause heartburn, such as rich, spicy, fatty and fried foods, chocolate, caffeine, alcohol and even some fruits and vegetables.
$10.84
SALE
−$1.26
Amazon Basic Care Maximum Strength Famotidine Tablets 20 mg, Acid Reducer Pills for Heartburn Relief, 200 Count (Packaging may vary)
- ACTIVE INGREDIENT: This product contains 20 mg of famotidine, an acid reducer for heartburn relief, which compares to the active ingredient in Maximum Strength Pepcid AC.
- RELIEVES HEARTBURN: Amazon Basic Care Maximum Strength Famotidine Tablets 20 mg help to relieve heartburn due to acid indigestion and sour stomach. PREVENTS
- HEARTBURN: Taken 10 to 60 minutes ahead of time, Amazon Basic Care Famotidine Tablets 20 mg prevents heartburn due to acid indigestion brought on by eating and drinking certain foods and beverages. JUST
- ONE TABLET prevents and relieves heartburn due to acid indigestion brought on by eating and drinking certain foods and beverages. This heartburn medicine lasts up to 12 hours. Use for adults & children 12 years and over. This product is gluten free.
- HEARTBURN MEDICINE: The active ingredient in Amazon Basic Care Famotidine Tablets 20 mg is an H2-blocker, which works as an acid reducer to help relieve heartburn. Lasts up to 12 hours. Use for adults and children 12 years and over.
$10.91
TUMS Chewy Bites Antacid Tablets for Chewable Heartburn Relief and Acid Indigestion Relief, Assorted Berries - 60 Count
- Comes in a container
- Reduces stomach acid
- Take two or three
- Instantly neutralizes acid
- Take on the go
$9.98
SALE
−$0.76
Amazon Basic Care Heartburn & Gas SuperChews Chewable Tablets, Mixed Berry, 82 Count (Previously SoundHealth)
- Chewy Not Chalky: Fast-acting relief for heartburn, gas, sour stomach, and bloating from 750 mg of calcium carbonate and 80 mg of Simethicone in an enjoyable product form
- Full of Flavor: Delicious mixed berry flavors are easily accessible in an easy-to-open flip cap bottle. Adults and children 12 years and up can take 1-2 chewable tablets every 2-4 hours as needed.
- Same Benefits, Lower Cost: Amazon Basic Care Antacid Fruit Chews are formulated to include the same active ingredients and provide the same relief as the name brand, but at a lower price to consumers
- This product was previously a SoundHealth product. Now it’s a part of the Amazon Basic Care Brand, the product is the exact same formulations, size, and quality.
- An Amazon Brand
$9.09
SALE
−$1.49
GoodSense Omeprazole Delayed Release Tablets 20 mg, Stomach Acid Reducer for Frequent Heartburn Treatment, 42 Count
- ACTIVE INGREDIENT: The active ingredient in these delayed release tablets is omeprazole 20 mg, which works as an acid reducer to treat frequent heartburn. Compare to Prilosec OTC
- TREATS FREQUENT HEARTBURN: GoodSense Omeprazole Delayed Release Tablets 20 mg treat frequent heartburn that occurs 2 or more times a week
- ACID REDUCER: GoodSense Omeprazole Delayed Release Tablets 20 mg is a Proton Pump Inhibitor (PPI) that deactivates pumps in the stomach lining to inhibit acid production at the source.
- 14-DAY COURSE OF HEARTBURN TREATMENT: Taken once every 24 hours for 14 days, GoodSense Omeprazole Delayed Release Tablets 20 mg is not intended for immediate relief of heartburn and may take 1 to 4 days for full effect.
- FREQUENT HEARTBURN FROM GLP-1? Try GoodSense Esomeprazole and continue on your weight loss journey. Use as directed. Not for immediate relief.
$14.50
SALE
−$3.22
Amazon Basic Care Esomeprazole Magnesium Delayed Release Capsules, 20 mg, Acid Reducer, Heartburn Medicine, 42 Count
- EFFECTIVE: Active ingredient in Amazon Basic Care Esomeprazole Magnesium Delayed Release Capsules, esomeprazole, 20 mg, acid reducer; compare to the active ingredient in Nexium 24 HR
- ACID REDUCER: Inhibits acid production at the source; enjoy foods and beverages that could cause frequent heartburn
- PROVEN HEARTBURN TREATMENT: Clinically proven to treat frequent heartburn that occurs 2 or more days a week
- HEARTBURN TREATMENT: Take once every 24 hours for 14 days; this heartburn medicine may take 1 to 4 days for full effect
- GLUTEN FREE: Amazon Basic Care Esomeprazole Magnesium Delayed Release Capsules, 20 mg; gluten free
$12.50
SALE
−$6.35
Gaviscon Extra Strength Cherry Chewable Tablet For Fast-Acting Heartburn Relief, 100 Count
- Gaviscon provides fast acting, long lasting heartburn relief and is an acid reflux remedy (when used as directed)
- Relieves heartburn, sour stomach, acid indigestion, and upset stomach associated with these symptoms
- Quickly neutralizes stomach acid and helps keep acid down for hours (when used as directed)
- Gaviscon is gastroenterologist recommended for heartburn and is available in both liquids and chewable tablets
- Gaviscon Extra Strength Tablet Antacid Cherry flavor contains the active ingredients aluminum hydroxide and magnesium carbonate
$9.64
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API