Flea control for cats is essential for maintaining your feline friend's health and comfort. In 2025, the market offers a variety of effective solutions, ranging from topical treatments and oral medications to natural remedies and flea collars. Each product is designed to target fleas at different life stages, ensuring comprehensive protection. When selecting the best flea control for your cat, consider factors such as age, weight, and any existing health conditions. With the right choice, you can keep your cat flea-free and happy.
Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 2-Month Supply
- Advantage II Large Cat is a leading brand in cat flea treatment and prevention for large cats over 9 lbs., at least 8 weeks of age
- Vet-recommended, easy-to-apply monthly topical treatment – no hard-to-swallow pills, no prescription needed
- Delivers total flea protection – kills adult fleas, flea larvae and flea eggs through contact
- Same-day effectiveness – kills fleas within 12 hours of application and keeps working for 30 days
- Fragrance-free formula, waterproof after 24 hours of application
$33.58
Amazon Basics Flea and Tick Topical Treatment for Cats (over 1.5 lbs), 6 Count (Previously Solimo)
- Same product, new look―This product is identical in manufacturing and formulation as the Solimo brand
- One 6 dose pack of Amazon Basics Flea & Tick Treatment for Cats (over 1.5 lbs)
- Amazon Basics Flea & Tick starts eliminating fleas and ticks within 24 hours of treatment
- Active ingredients (list ingredients) prevent flea infestations by killing flea eggs, flea larvae, mosquitos, biting flies and chewing lice
- One application provides up to 30 days of protection
$24.29
Seresto Cat Vet-Recommended Flea & Tick Treatment & Prevention Collar for Cats | 8 Months Protection
- Vet-recommended, premium flea & tick protection for cats & kittens without the price tag
- Long-lasting flea and tick collar kills & repels fleas for 8 continuous months
- Seresto is the #1 veterinarian recommended flea & tick collar*
- Starts working within 24 hours to kill & repel fleas and ticks by contact so pests don’t have to bite your cat to die
- Hassle-free, non-greasy, easy-to-use flea & tick protection
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Advantage II Small Cat Vet-Recommended Flea Treatment & Prevention | Cats 5-9 lbs. | 2-Month Supply
- Advantage II Small Cat is a leading brand in cat flea treatment and prevention for small cats 5-9 lbs., at least 8 weeks of age
- Vet-recommended, easy-to-apply monthly topical treatment – no hard-to-swallow pills, no prescription needed
- Delivers total flea protection – kills adult fleas, flea larvae and flea eggs through contact
- Same-day effectiveness – kills fleas within 12 hours of application and keeps working for 30 days
- Fragrance-free formula, waterproof after 24 hours of application
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SALE
−$2.00
Flea and Tick Prevention for Cats & Kittens: Waterproof Topical Cat Flea and Tick Treatment – Fast-Acting & Long-Lasting At Home Flea Control for Cats Over 1.5 lbs and 8 Weeks or Older – 6-Dose Supply
- Flea & Tick Treatment for Cats: Our cat flea and tick treatment is formulated with vet-approved ingredients to quickly treatment fleas, ticks, larvae, and eggs, providing up to 30 days of continuous protection against
- Safe & Gentle for All Cats: Designed specifically for cats, our formula is safe for felines weighing over 1.5 lbs, making it suitable for kittens, adult cats, and senior cats. Gentle and non-irritating, it's ideal for cats with sensitive skin.
- Easy-to-Use: Our topical cat flea treatment is applied directly to the shoulder blades, eliminating the stress of administering oral medications. A simple, mess-free solution for effective flea and tick control.
- Everyday Protection: Our flea treatment for cats becomes waterproof 24-48 hours after application, allowing your cat to bathe and play as usual without compromising effectiveness—protection that lasts an entire month.
- Prevents Reinfestation: Not only does it eliminate existing fleas and ticks, but it also prevents new infestations by disrupting the parasite life cycle. A complete flea and tick prevention for cats solution for long-term health and comfort.
$26.99
Amazon Basics Flea Topical for Large Cats (over 9 pounds), 4 Count (Previously Solimo)
- FAST-ACTING FLEA MEDICATION FOR CATS: Eliminates fleas in just 12 hours, providing your large cat with swift relief from discomfort with our effective flea medication for cats
- LONG-LASTING FLEA PREVENTION FOR CATS: Protect your cat from infestations for up to 4 weeks with each application of this flea remover, providing continuous and reliable flea prevention for cats
- TOPICAL CAT FLEA DROPS FOR REINFESTATION: This cat flea medicine proactively kills reinfesting fleas within 2 hours, efficiently halting the flea lifecycle
- SUITABLE CAT FLEA MEDS FOR LARGE CATS: Specifically formulated for cats weighing over 9 pounds, offering targeted flea control with our dedicated cat flea meds for your furry companion
- SUITABLE CAT FLEA MEDS FOR LARGE CATS: Specifically formulated for cats weighing over 9 pounds, offering targeted flea control with our dedicated cat flea meds for your furry companion
$23.27
Woyamay Flea Treatment for Cats, 200 Treats Flea and Tick Prevention for Cats Chewables, Natural Cat Flea and Tick Treatment Chews Daily Oral Flea Supplement, Kitten Cat Flea Treatment, Chicken Flavor
- NATURAL CAT FLEA AND TICK TREATMENT: Our cat flea treatment chews are made with natural ingredients and offer a gentle way to prevent fleas and ticks from the inside out, keeping your cat comfortable and protected. This veterinarian-approved formula provides gentle oral flea chewable for cats and kittens. Each can contains 200 chews, offering over 3 months of use
- DAILY PROTECTION, LONG-TERM DEFENSE: Woyamay cat flea and tick prevention chewable treats provide daily protection and help reduce the impact of fleas, ticks, mosquitoes, and so on. They help your cat develop a natural defense against fleas and ticks from within and are suitable for small, medium, and large cats. An easy and pet-friendly alternative to flea drops, spray, and shampoo
- EFFECTIVE HEALTH SUPPORT: Our oral flea and tick prevention for cats chews provide natural health support for cats of all ages and breeds. Each soft chew is enriched with coconut oil, flaxseed, and brewer's yeast, and contains no harsh chemicals or artificial additives. Gentle for both kittens and senior cats, these flea chews offer a gentle yet effective flea prevention solution
- SKIN & COAT CARE: Our flea and tick treatment for cats is formulated with skin-nourishing ingredients, including fish oil and B vitamins. These chews moisturize and protect your cat's skin while promoting a shiny, healthy coat. With consistent use, they improve coat appearance and support effective prevention of fleas and ticks
- DELICIOUS & EASY TO USE: Our Woyamay cat and kitten flea treatment chews feature a delicious chicken flavor that even picky eaters will love. They are easy to administer—simply offer them as treats or crush and mix them into a meal for effortless serving. Our tasty chicken-flavored chewables make oral flea prevention for cats a snack, not a chore
$23.99
TevraPet Actispot II Flea Treatment for Large Cats 9+ lbs | 6 Doses | Powerful Prevention and Control
- POWERFUL FLEA KILLING TREATMENT FOR LARGE CATS: TevraPet Actispot II is a waterproof topical for cats that kills fleas, flea eggs, and flea larvae for up to 30 days after each application
- VET APPROVED FORMULA: TevraPet Actispot II uses Imidacloprid and Pyriproxyfen - the same safe and effective active ingredients found in Advantage II - but costs far less. Every cat deserves veterinarian quality treatment, Actispot II helps you provide the same level of care without breaking the bank
- FAST ACTING AND LONG-LASTING WITH NO BITING REQUIRED: TevraPet Actispot II REPELS and KILLS fleas on contact, without your cat being exposed to bites. Begins killing within 24 hours of application, and starts repelling immediately. Other oral flea tablets, pills, and chews require that your pet is bitten by a pest before the meds can start working, potentially exposing your kitty to flea borne diseases
- BREAK THE CYCLE, PREVENT REINFESTATION: Unlike other flea medications that only temporarily control fleas, Actispot II flea treatment stops infestations dead in their tracks by effectively breaking the flea life cycle. Actispot II safely kills flea eggs and larvae to prevent re-infestation so your cat can get on with napping in the sun and strolling (or stalking!) through the garden
- EASY-TO-USE, MADE IN AMERICA: We proudly make every dose of Actispot II here in the USA and rigorously test for quality and potency. Each package comes with six (6) easy to apply, fully waterproof topical applications that ensure your friend has safe and reliable flea protection and control for up to six (6) months
$29.97
TevraPet FirstAct Plus Flea and Tick Topical for Cats over 1.5lbs, 3 Dose Waterproof Flea and Tick Control/Prevention for 3 Months
- Proven formula - Contains fipronil and (S)-Methoprene, the same active ingredients as Frontline Plus for cats
- Effective - This flea and tick topical kills fleas, flea eggs and larvae, chewing lice, and all stages of ticks including those that may transmit Lyme disease
- Waterproof - use on your cat monthly, no need to reapply after swimming or bathing
- 3 month supply - includes 3 applicators for 3 months of flea and tick Prevention; Apply these flea drops Once every 30 days
- Trusted quality - made in Germany in a certified eu-gmp facility, tested to meet rigorous standards of quality and consistency
$19.97
Cheristin Flea Treatment & Prevention for Cats | Fast acting topical flea treatment for cats over 1.8 lbs | 6 Count
- Cheristin is a fast-acting topical flea treatment for cats
- Starts to kill fleas in only 30 minutes, kills 98-100% of fleas in 12 hours
- Convenient one-size-fits-all dose is good for all cats and kittens (1.8 lbs. and greater and 8 weeks of age and older) and a great addition to multi-cat households
- Easy-to-apply from a small applicator with a rounded tip
- Long-lasting (through 6-weeks) flea protection your cat deserves
$78.69
Last update on 2025-05-03 / Affiliate links / Images from Amazon Product Advertising API