Flea and tick meds for dogs are essential for keeping your furry friend safe and healthy. In 2025, pet owners have a variety of effective options to choose from, ensuring protection against these pesky parasites. From topical treatments to oral medications, the best products not only eliminate existing infestations but also provide long-lasting prevention. It's crucial to select a medication that suits your dog's specific needs, taking into account factors like age, weight, and any pre-existing health conditions. With the right flea and tick prevention, you can enjoy peace of mind knowing your dog is protected.
SALE
−$5.01
FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments
- Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
- Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control
- Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days
- FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products
- Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
$39.98
K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs. | 1-Mo Supply
- K9 Advantix II Large Dog 30-day treatment & prevention protects dogs 21-55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
- Kills fleas within 12 hours of application
- Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
- Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
- No prescription needed
$18.98
Amazon Basics Flea and Tick Topical Treatment for Small Dogs (5 -22 pounds), Unscented, 6 Count (Previously Solimo)
- Same product, new look – This product is identical in manufacturing and formulation as the Solimo brand
- One 6 dose pack of Amazon Basics Flea and Tick Topical Treatment for Small Dogs (5 - 22 pounds), 6 Count (Previously Solimo)
- Amazon Basics Flea & Tick starts eliminating fleas and ticks within 24 hours of treatment
- Active ingredients Fipronil and (s)-methoprene prevent flea infestations by killing flea eggs, flea larvae, mosquitos, biting flies and chewing lice
- One application provides up to 30 days of protection
$28.87
SALE
−$5.01
FRONTLINE Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments
- Keep your dog protected from fleas & ticks all month long with FRONTLINE Plus for Dogs a fast-acting, waterproof flea & tick topical that's proven to kill fleas, flea eggs, flea larvae, chewing lice, and ticks that can transmit Lyme disease
- Break the flea life cycle with FRONTLINE Plus, specially formulated with fipronil and (S)-methoprene to kill existing adult fleas, flea eggs and flea larvae to guard against further infestations for flea control
- Trusted by pet owners for over 20 years, FRONTLINE Plus for Dogs can be used on puppies as young as eight weeks old, weighing 5 pounds or more, and is easy to apply with one monthly dose providing protection from fleas & ticks for a full 30 days
- FRONTLINE Plus also comes in a formula designed for cats and kittens eight weeks of age and older, 1.5lbs. and over, so you can protect the dogs or cats in your house from fleas and ticks with FRONTLINE Brand Products
- Treat all dogs or cats in your household monthly to effectively control fleas and ticks and prevent the establishment of new flea infestations
$39.98
K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 2-Mo Supply
- K9 Advantix II Extra Large Dog 30-day treatment & prevention protects dogs over 55 lbs. from fleas, ticks, mosquitoes, biting flies and lice
- Kills fleas within 12 hours of application
- Vet-recommended formula kills & repels on contact so fleas don’t have to bite your dog to die
- Easy-to-apply topical treatment is fragrance-free and waterproof after 24 hours
- No prescription needed
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TevraPet Activate II Flea and Tick Prevention for Dogs | 4 Count | Extra Large Dogs 55+ lbs | Topical Drops | 4 Months Flea Treatment
- COMPARE TO K9 ADVANTIX II: Activate II uses Imidacloprid, Permethrin, and Pyriproxyfen - the same safe, fast acting active ingredients used in Advantix II for Dogs. Includes 4 monthly doses
- ACTIVELY PROTECTS YOUR DOG: Activate II is approved by veterinarians to repel and kill fleas and ticks on contact - before your dog is exposed to bites and potential flea borne illnesses
- STOP INFESTATIONS FAST: Our topical drops prevent infestations by breaking the flea life cycle - our insect growth regulator (IGR) starts killing flea eggs and larvae within 12 hours of application
- EASY TO APPLY: Simply apply to the base of your dog's neck, and the waterproof solution will travel across the skin - providing continuous protection for 30 days per application
- MADE IN AMERICA - RESULTS GUARANTEED: TevraPet Activate II is made to the quality standard we demand for our own pets. We're proud to help you protect your dog with confidence
$26.97
SALE
−$4.06
PetArmor Plus Flea and Tick Prevention for Dogs, Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting, Small Dogs (5-22 lbs)
- EFFECTIVE, WATERPROOF FLEA TREATMENT FOR DOGS: PetArmor Plus is a waterproof, flea & tick topical prevention for dogs that kills fleas, flea eggs, flea larvae, ticks, and chewing lice for up to 30 days after application.
- TRUSTED, VET QUALITY FORMULA: Containing fipronil and (S)-methoprene, the same active ingredients as FRONTLINE Plus for Dogs. PetArmor Plus for Dogs has a powerful formula that starts to kill fleas within 24 hours.
- BREAK THE FLEA CYCLE: Unlike other flea and tick treatments that may temporarily suppress flea activity, PETARMOR Plus Dog Flea Treatment works by effectively breaking the flea life cycle. Kill flea eggs and larvae to prevent re-infestation.
- FAST ACTNG LONG-LASTING FLEA AND TICK PROTECTION: One application of PetArmor Plus lasts up to 30 days nose to tail. A 6-dose package lasts up to six months.
- EASY-TO-USE, LONG-LASTING: PetArmor Plus flea and tick treatment comes with three (3) waterproof topical applications that provides your pet flea protection and control for three (3) months.
$24.93
Amazon Basics Flea and Tick Topical Treatment for Medium Dogs (23-44 lbs), 3 Count (Previously Solimo)
- FAST-ACTING RELIEF: Amazon Basics Flea and Tick Treatment for dogs starts eliminating fleas and ticks in just 24 hours. Waterproof within 24 hours as well
- LONG-LASTING PROTECTION: One easy application of our dog flea & tick control offers up to 30 days of flea prevention for dogs
- COMPREHENSIVE PEST CONTROL: Our topical treatment kills fleas, flea eggs, flea larvae, ticks, and lice
- EFFECTIVENESS: This long-lasting flea medicine for dogs is formulated to target and eliminate deer ticks, helping to prevent Lyme disease
- SIMPLE MONTHLY APPLICATION: Apply this topical flea treatment on medium-sized dogs once a month to maintain up to 30 days of protection
$17.45
Flea and Tick Prevention for Dogs Chewables - 170 Treats - Natural Dog Flea and Tick Treatment Chewable Supplement - Oral Pills - All Breeds & Ages - Soft Chews - Made in USA
- Natural Flea & Tick Prevention: Defend your dogs from pests the natural way with our flea prevention for dogs - a safer alternative for itch-free protection
- Optimal Protection: To achieve the best outcomes, administer our chewable flea and tick prevention tablets to your dog on a daily basis. This helps establish the necessary levels in their system for effective protection.
- Suitable for All Breeds and Ages: Whether you’re caring for a teacup pup or a gentle giant, our flea chews for dogs are designed to keep dogs of all breeds and ages happily protected
- Veterinarian Formulated & USA Made: Trust in the premium quality of our dog flea & tick control chews, which are formulated by veterinarians and manufactured in the USA within an FDA-registered facility
- Hassle-Free Administering: Forget the struggle of topical treatments - our tasty chicken-flavored chewables make administering flea and tick prevention a treat, not a chore
$23.99
Amazon Brand - Solimo for Dogs Large Dog (45-88 pounds) Flea and Tick Treatment, 6 Doses
- FAST-ACTING RELIEF: Begin eliminating fleas and ticks within 24 hours of application, providing relief for your large dog
- LONG-LASTING PROTECTION: This flea treatment for dogs offers up to 30 days of coverage, protecting your pet from harmful pests
- INFESTATION CONTROL: Active ingredients in this dog flea medicine target eggs, larvae, adult fleas, as well as mosquitoes, lice, and flies
- FOR LARGE DOGS: Specifically designed for dogs weighing 45-88 pounds, providing a precise and effective flea and tick solution
- FORMULA: This topical flea treatment for dogs contains Fipronil and (s)-methoprene
$28.48
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API