Fever blister medicine is essential for anyone looking to alleviate the discomfort and speed up the healing process of cold sores. In 2025, the market offers a variety of effective treatments, ranging from topical creams to oral medications, each designed to target the herpes simplex virus responsible for these painful blisters. Some of the top-rated options include antiviral ointments, natural remedies, and over-the-counter solutions that provide quick relief and promote healing. Choosing the right fever blister medicine can make a significant difference in managing outbreaks and minimizing symptoms.
SALE
−$9.23
Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Tube x 2
- Number 1 Cold Sore Brand: Two 0.07 oz tubes of Abreva 10 Percent Docosanol Cold Sore Treatment
- Can Heal in 2.5 Days: Fever blister cream contains 10 percent docosanol to shorten the duration of cold sore symptoms (1)
- Nothing Heals Fever Blisters Faster: 10 percent docosanol cream penetrates deep into skin to tackle cold sores at their source (1, 2, 3)
- Lip Cream Clinically Proven to Shorten Duration of Symptoms: Cold sore product shortens duration of tingling, pain, burning and itching associated with cold sores (1)
- Portable Cold Sore Cream: Packaged in a convenient tube for on the go cold sore treatment
$25.00
SALE
−$4.75
Campho Phenique Cold Sore and Fever Blister Treatment for Lips, Maximum Strength Provides Instant Relief, Helps Prevent Infection To Promote Healing, Original Gel Formula, 0.23 Oz
- Trusted: A favorite for cold sore and fever blister treatment for lips for over 130 years.
- Instant Relief: Formulated with camphor and phenol to temporarily inactivate the pain signals at the nerve endings in the skin to provide a local anesthetic (numbing effect) that stops the pain and itch of cold sores and fever blisters on contact.
- Helps Prevent Infection: Antiseptic properties help prevent infection to promote cold sore healing.
- Aloe Soothes and Moisturizes: Prevents dryness and cracking as cold sores and fever blisters dry out.
- Store at room temperature
$4.24
SALE
−$4.00
Mederma Fever Blister Discreet Healing Patch - A Patch That Protects and Conceals Cold Sores - 15 Count
- INSTANTLY HIDES COLD SORES: Avoid the social embarrassment of a cold sore; the discreet protective barrier instantly hides unsightly fever blisters on the lips or mouth
- FASTER HEALING: The patch hydrocolloid gel technology creates an optimal healing environment so your skin heals fast
- 12 HOUR PROTECTION: Each patch provides up to 12 hours of non-stop protection from contamination to the cold sore; apply as early as day 1 to relieve pain
- EASY TO USE: The discreet patches have a no touch applicator; they're easy to apply and they stay in place to help conceal your cold sore
$9.99
SALE
−$2.51
Quantum Health Lip Clear Lysine+ Cold Sore Treatment Soothe & Moisturize Mouth Sores - L-Lysine Menthol Calendula & Propolis Ointment - Transparent Fever Blister Healing Balm - 0.25 Oz
- HALVE YOUR HEALING TIME - Cut cold sore healing time by 50% with the power of L-Lysine, a scientifically researched amino acid that inhibits arginine activity, nourishes skin and accelerates recovery.
- FAST-ACTING PAIN & ITCH RELIEF - Experience rapid relief from cold sore pain, burning, and itching discomfort with the cooling effect of Menthol plus 14 herbal ingredients to soothe and nourish your skin.
- HERBAL LIP TREATMENT - Harness the power of our nutrient-rich formula with Calendula, Vitamin E, and Propolis, providing deep moisturization and skin-nourishing properties for overall lip health.
- DISCREET COMFORT - Invisible balm can be worn under lipstick or gloss without worry, doesn't burn upon application, and offers relief from tingling, itching, burning, and other discomforts associated with cold sores.
- ROUND OUT YOUR LIP CARE ROUTINE - For optimal results use Lysine+ Ointment with our Super Lysine Immune Support Tablets and Lip Clear Invisible Cold Sore Patch to calm cold sores and promote faster healing.
$7.48
TARO Cold Sore/Fever Blister Treatment - Docosanol 10% Cream (0.07 oz - 2 Tube)
- Docosanol Cream 10% – Treats cold sores/fever blisters
- Treats Cold Sores / Fever Blisters on the Face or Lips
- Shortens Healing Time and duration of Symptoms
$14.99
Abreva Cold Sore Treatment Rapid Pain Relief Cream - 1 Tube, 3 Grams
- One tube of Abreva Cold Sore Rapid Pain Relief, 3 grams.
- Shortens duration of tingling, pain, burning and itching
- Easy applicable tube form for on-the-go use
- When you feel pain and burning from the cold sore or blister, Abreva has you covered with Abreva Rapid Pain Relief gel
- It delivers quick, targeted relief from the first application
$12.47
SALE
−$0.70
Herpecin-L Pain Relief Treatment for Cold Sores and Fever Blisters, with Lidocaine, numbs Pain and Itch, Protects Against Infection, 0.15 oz
- RAPID RELIEF + INFECTION PROTECTION. Instantly shorten tingling, pain and itching with lidocaine AND helps protects against infection.
- SHORTEN the duration of tingling, pain, buring, and itching AND protect against infection which will lengthen the cold sore.
- PREVENT PAINFUL CRACKING: hydrating formula with allantoin, aloe, and glycerin soothes and softens to prevent painful cracking and reopening of cold sore.
- PROTECT AGAINST INFECTION: Maximum strength antiseptic helps keep the cold sore from getting infected and promote healing.
- NO BURNING. No menthol, no camphor, no irritation, goes on clear
$9.29
Zilactin Early Relief Cold Sore Treatment - Fast Relief of Cold Sores and Fever Blisters, Made in USA, 0.25oz Gel, Pack of 1
- Unique Formula: Zilactin's uniquely blended formula includes a 10% concentration of Benzyl Alcohol for targeted treatment and fast relief of cold sores and fever blisters
- Bioadhesive Technology: Zilactin's cold sore treatment creates a discreet, invisible protective barrier over your sore for long-lasting protection and relief
- Fast, Long-Lasting Relief: Up to 6 hours of protection and pain relief with a single application
- Feel It. Heal It: Initial sting, followed by long lasting relief and recovery
- Made in USA: Assures quality and reliability in every application
$9.98
SALE
−$8.37
Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Pump
- Number 1 Cold Sore Brand: One 0.07 oz pump bottle of Abreva 10% Docosanol Cold Sore Treatment
- Can Heal in 2.5 Days: Fever blister smooth, white cream contains 10% docosanol to shorten the duration of cold sore symptoms (1) by blocking the virus from infecting healthy cells
- Nothing Heals Fever Blisters Faster: FDA approved medicine to shorten cold sore healing time
- Lip Cream Clinically Proven to Shorten Duration of Symptoms: Cold sore product shortens duration of tingling, pain, burning and itching associated with cold sores (1)
- Portable Cold Sore Cream: Packaged in a convenient pump bottle for on the go cold sore treatment
$14.84
Last update on 2025-05-03 / Affiliate links / Images from Amazon Product Advertising API