Enzyme cleaner for dog urine is essential for pet owners looking to effectively eliminate stubborn stains and odors. These specialized cleaners break down the proteins in urine, ensuring that both the smell and the potential for repeat marking are addressed. In 2025, several top-rated enzyme cleaners stand out for their effectiveness, safety, and ease of use, making them a must-have for any dog owner. From natural formulations to powerful enzymatic solutions, these products cater to various needs and preferences, ensuring a clean and fresh home environment.
Rocco & Roxie Stain & Odor Eliminator for Strong Odor, 32oz Enzyme Pet Odor Eliminator for Home, Carpet Stain Remover for Cats & Dog Pee, Enzymatic Cat Urine Destroyer, Carpet Cleaner Spray
- Certified Gentle And Safe: Chlorine free and color safe; Safe to use around pets and children; No hazardous propellants, no residue left behind. So gentle it’s been Certified Safe for all carpets, earning the Seal of Approval by the trusted Carpet and Rug Institute (cri)
- Eliminates Stains, Odors and Residue: If it’s gross, it’s gone; Not just the stain, but the stink; From stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all
- Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen
- Enzyme Activated: The key is getting to the problem deep-down; This spray contains natural enzymes that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated
- Buy With Confidence: You want the best for your best friend; We do, too; If you are not satisfied with the performance of this product, contact us; We are determined to make it right
$23.92
SALE
−$2.29
Nature's Miracle Urine Destroyer Plu for Dogs, Enzymatic Formula for Severe Dog Urine Stains, 32 fl oz
- FOR DOG URINE MESSES: Begins to break down and remove stains immediately on contact.
- POWERFUL FORMULA: Just soak the affected area, allow to work for 15 minutes, then blot up stain with a clean cloth.
- ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
- MADE WITH RECYCLED MATERIAL: Our bottles are made with 25% Post-Consumer Recycled Material.
- SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets and in your home
$12.70
SALE
−$2.24
Nature’s Miracle Stain and Odor Remover Dog, 32 Ounces, Odor Control Formula
- SPOT STAIN & ODOR REMOVER: Begins to break down and remove stains immediately on contact.
- LIGHT CITRUS SCENT: Dog odor control formula gets your home smelling clean again.
- ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
- TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works!
- SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets.
$10.75
AmazonCommercial Multi-Purpose Enzyme Cleaner, 1-Gallon, 1-Pack
- 1 gallon bottle of multi-purpose enzyme cleaning solution for a wide variety of surfaces and environments
- Breaks up complex organic proteins, pet smells and stains, hair, grease, oils, and more for effective results
- Ideal for commercial properties, retail, and hospitality
- Use as needed on stains and problem areas for spot cleaning carpet, surfaces, drains, toilets, grease traps, and more
$33.29
Bioda Multi-Purpose Probiotic Enzyme Cleaner and Deodorizer | Professional Strength | Trash Can Deodorizer, Pet Stains and Odors, Drains, Floors, Bathrooms, Toilets | Made in USA | 1 Gallon
- THE POWER OF ONE: This versatile product is the only probiotic cleaner you need, providing powerful cleaning performance in a wide variety of applications. Multipurpose use: Maintain clean drain lines and septic tanks to prevent clogs and potential buildup. Clean and deodorize trash bins, stains and odors on floors, carpets, bathroom surfaces, kitchen surfaces, and more.
- ACTIVE UP TO 21 DAYS: Our specialized probiotics continue to clean soils in cracks, grout and tough to reach places. Simply spray & let the probiotics do the dirty work!
- NATURALLY, SUPERIOR RESULTS: A special blend of enzyme-producing probiotics break down complex proteins, fats, oils, greases, and other organic waste. The enzymes digest the soils until they have been eliminated, providing a long-lasting, continuous clean without leaving a residue or harmful by-products behind.
- ELIMINATE ODOR: Provide total odor control by eliminating the actual source of even the most pungent organic malodors naturally, including rotting food, urine, feces, vomit, and trash. Plus, the fresh lemon and sage fragrance leaves behind a light, pleasant scent that rejuvenates the air of any environment.
- MADE IN THE USA - 1 Gallon Bottle
$25.95
SALE
−$2.44
Nature’s Miracle Advanced Stain and Odor Eliminator Dog Spray, Fresh Scent, Severe Mess Enzymatic Formula For Tough Pet Messes, 32 Ounces
- FOR SEVERE DOG MESSES: Powerful enzymatic formula works to eliminate tough stains and odors from dog urine, diarrhea, vomit and other bio-based accidents.
- LIGHT FRESH SCENT: Dog odor control formula gets your home smelling clean again.
- ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
- DISCOURAGES RESOILING: Removes the odor from even the toughest dog messes.
- TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works!
$13.55
Simple Solution Extreme Pet Stain and Odor Eliminator Spray, Enzymatic Cleaner With 3X Pro-Bacteria Cleaning Power for Dogs & Cats, Strong Urine, Pee and Poop Smell Remover for Carpets & Floors, 32 oz
- PET STAIN AND ODOR REMOVER: Things can get a little messy when your pet is involved - that’s where we come in; This extra-strength cleaning solution is specially formulated to tackle the toughest smells & dirtiest spots left behind by your beloved pets.
- EXTREME ENZYMATIC CLEANER: This professional strength spray consists of a powerful enzyme formula three times stronger than our regular formula, specialized for breaking down, eliminating, and permanently neutralizing both new and old stains and odors.
- FOR DOGS AND CATS: Say goodbye to bad messes - This dog and cat-specific cleaning spray is the best thing for cleaning up after urine, feces, vomit, and all the stains and smells that accompany them; It is a pet-safe and family-friendly cleaning option
- MULTIFUNCTION SPRAY: This cleaner can be used for carpets, upholstery, bedding, fabric toys, clothing, & other water-safe surfaces in your home; It uses a patented 3-in-1 nozzle with mist, foam, and stream features so you can pick the best way to clean up
- SIMPLE SOLUTION: it’s just that…a simple solution to all of your pets’ messes – wherever they may be; We offer easy-to-use, no-hassle products that will effectively help you keep your home clean and sparkling; In short - pet parenting made easy.
$7.26
Resolve Urine Destroyer Spray – Pet Stain and Odor Remover, Carpet Cleaner Solution for Cat and Dog Urine, 32 Fl Oz
- DESTOYS URINE ODORS THE FIRST TIME: Urine elimination technology neutralizes and removes odors on contact for immediate freshness
- REMOVES PET STAINS AND MORE: Effectively tackles pet stains, food stains, and other tough messes
- HELPS PREVENT REMARKING: Discourages pets from returning to make a mess in the same spot
- SUITABLE FOR USE AROUND PETS: Suitable for use around pets when used as directed
- MULTIPURPOSE USE: Effective on most carpets, fabrics and hard surfaces for versatile cleaning
$9.98
SALE
−$5.04
Nature's Miracle Stain and Odor Remover Dog, Odor Control Formula, Accushot Spray 1.33 Gal
- SPOT STAIN & ODOR REMOVER: Begins to break down and remove stains immediately on contact
- LIGHT CITRUS SCENT: Dog odor control formula gets your home smelling clean again
- ACCUSHOT SPRAYER REFILL: Use alone or with the AccuShot continuous power sprayer (sold separately)
- ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present
- SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets
$27.45
Angry Orange Stain Remover - 32oz Enzyme Pet Cleaner - Dog & Cat Urine Destroyer and Stain Remover - Citrus Spray Cleaning Solution - Puppy Supplies
- POWERFUL 2 IN 1 ENZYME STAIN + ODOR FIGHTING - Angry Orange enzyme-active cleaner breaks down and eliminates stains from pet urine, feces and vomit.
- MULTIPURPOSE - Can be used to eliminate stains from carpet, tile, hardwoord, couch upholstery, car interiors, turf, and more.
- DIRECTIONS FOR USE - For best results, remove pets from area, clean excess mess, shake well & spray, let enzymes eat away at the stains.
- CITRUS SCENT - Angry Orange Enzyme Cleaner will break down, not mask, your stains and leave a fresh citrus smell.
- CUSTOMER SERVICE - If you're not satified reach out to our responsive customer service team.
$19.95
Last update on 2025-05-04 / Affiliate links / Images from Amazon Product Advertising API