Drain cleaner for main line is essential for maintaining a healthy plumbing system and preventing costly clogs. In 2025, the market offers a variety of effective solutions designed to tackle tough blockages in your main sewer line. From powerful enzymatic cleaners to heavy-duty chemical formulations, these products are formulated to break down grease, hair, and other debris that can lead to backups. Choosing the right drain cleaner can save you time and money while ensuring your plumbing remains in top condition. Explore the top options available to find the best fit for your needs.
SALE
−$2.87
Roebic K-97 Main Line Cleaner: Exclusive Bacteria Digests Paper, Fats, and Grease in Sewer and Septic Systems - 32 Ounces, Liquid
- 32oz concentrated bacterial waste degrading product clears fats, grease, sludge, & paper in any sewer line. Ideal for septic systems or sewer
- Safe for all pipes and the environment. Effectively clears fats, grease, sludge, and paper for optimal sewer and septic system maintenance
- Naturally breaks down waste, restores proper flow. Safe for all pipes, environment. Ideal for sewer, septic systems
- Keeps lines problem-free, ideal for low-flow toilets
- Re-treat your sewage system once a year for optimal performance and maintenance
$7.97
SALE
−$5.01
Green Gobbler Ultimate Main Drain Opener | Drain cleaner Hair Clog Remover | Works On Main Lines, Sinks, Tubs, Toilets, Showers, Kitchen Sinks | 64 fl. oz.
- HIGH-DENSITY MAIN LINE DRAIN OPENER. Ultimate Main Line Opener’s thick, high-density formula sinks through water and clings to pipes to liquify tough drain obstructions, clearing the main line to and from your home.
- DISSOLVES ORGANIC MATERIAL AND PAPER. Ultimate Main Line Opener dissolves grease, hair, oils, soap scum, baby wipes, and paper products easily.The revolutionary formula is great for both addressing clogs and preventive maintenance.
- NON-DAMAGING TO PIPES. Green Gobbler’s industrial-strength drain clog remover is tough where it counts. While it takes care of the toughest clogs, it remains gentle on pipes and septic systems.
- ENVIRONMENTALLY FRIENDLY AND SAFER TO USE. Ultimate Main Line Opener is safer to use than chemical-based cleaners. It’s odorless, non-flammable
- GREEN GOBBLER GUARANTEE: Green Gobbler cares about its customers. We take pride in developing innovative & effective products for your home or business. We offer a money-back guarantee within 30 days of purchase.
$24.98
PEQUA INDUSTRIES Main Line Cleaner - Heavy-Duty Main Drain Opener for Drain Pipes, Sewer Lines and Septic Tanks, Dissolves Hairs and Organic Matter, Safe for All Septic Systems (1 Gallon (Pack of 1))
- FROM GRIME TO SHINE IN NO TIME: Bring Pequa's Main Line Cleaner at your place to flushout all the blockage. With its generous one-gallon size, this cleaner offers an ample supply, suitable for extensive mainline severge cleanups.
- EFFICIENTLY DISSOLVES THE CLOG: Our heavy-duty pipe liquid cleaner dissolves hair, toilet paper, soap scum, and other organic materials that may block pipes. Ideal for both residential and commercial use, this drain opener ensures speedy, reliable results.
- SAFE AND EFFECTIVE: This non-acid Main Line Drain Cleaner is safe for both septic tank systems and larger pipelines. It contain potassium hydroxide which being a strong alkaline compound effectively clears the grease and control corroison.
- HASSLE-FREE USAGE: Pequa's Main Drain Cleaner requires minimal effort to address drain pipeline issues. Use one gallon of Mainline Cleaner for every 20 feet of mainline, use no water post usage for at least three hours preferably overnight , then proceeds with thorough flushing using lukewarm water.
- QUALITY ASSURANCE: The Main Line Opener is formulated to meet expert quality standards, ensuring smooth and effective drain unclogging experience. In addition to this, our mainline cleaner is odor-free and ensures a user-friendly environment. Strictly advised to avoid contact with skin, eyes and clothing etc.
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SALE
−$3.50
Green Gobbler Enzyme Drain Cleaner | Controls Foul Odors & Breaks Down Grease, Paper, Fat & Oil in Sewer Lines, Septic Tanks & Grease Traps | 1 Gallon
- ENZYME ENHANCED FORMULA: Green Gobbler Enzymatic Drain & Grease Trap Cleaner uses an enzyme enhanced formula to clear buildup and remove odors in grease traps, septic tanks and similar plumbing systems. It helps digests oils, fats, grease, sludge and other food waste within hours of application. This bottle uses anti-glug technology to help reduce splashing and provides up to eight treatments.
- SAFE FOR PIPES: Green Gobbler helps maintain drain lines, septic tanks, grease traps and grease interceptors. Our enzyme enhanced formula is an excellent alternative to sodium hydroxide and other caustic chemicals.
- IMPROVE GREASE TRAP EFFICIENCY: Green Gobbler increases the efficacy of grease traps by allowing enzymes & bacteria to work more efficiently to promote the separation of water and grease, helping your trap run more smoothly.
- KEEP SEPTIC TANKS HEALTHY: Green Gobbler helps prompt the biological breakdown of foul odors and organic material inside demanding environments such as drains, pipes and septic tanks.
- GREEN GOBBLER GUARANTEE: Green Gobbler cares about its customers. We take pride in developing innovative & effective products for your home or business. If for any reason you are unsatisfied, please contact us. We offer a money-back guarantee within 30 days of purchase.
$24.48
SALE
−$1.00
Amazing Products Liquid Fire Drain Line Opener, 32 Oz
- Liquid Fire provides professional results cleaning drain pipes in sinks, tubs, shower stalls, plus septic tanks and laterals
- As you Pour Liquid Fire into clogged or slow running drain, it reacts instantly creating heat
- Provides free running drain in freezing weather by chemically creating heat instantly
- It works faster and more effectively than most other popular cleaners and is more economical
$17.90
SALE
−$5.22
Green Gobbler Industrial Strength Grease and Hair Drain Clog Remover | Drain Cleaner Gel | Safe for Pipes, Toilets, Sinks, Tubs, Drains & Septic Systems | 1 Gallon
- ELIMINATE THE TOUGHEST CLOGS: Liquefy hair, grease, toilet paper, soap scum, organic material, flushable wipes and more. This bottle uses anti-glug technology to help reduce splashing and provides up to eight clog remover treatments.
- EASY TO USE: Forget the plumber. Pour Green Gobbler in standing water and it will do the rest. The Industrial Strength gel is our thickest formula to cling to clogs better and keep your pipes flowing properly.
- WORKS ON: Toilets, sinks, showers, tubs, and drains. It's safe for all pipes and septic tanks.
- BLEACH FREE FORMULA: Odorless and free of fumes, Green Gobbler Industrial Strength is an excellent alternative to traditional bleach-based drain openers.
- GREEN GOBBLER GUARANTEE: Green Gobbler cares about its customers. We take pride in developing innovative & effective products for your home or business. If for any reason you are unsatisfied, please contact us. We offer a money-back guarantee within 30 days of purchase.
$24.77
Ultimate Main Drain Opener | Drain Cleaner | Sewer Cleaner + Hair Clog Remover - Safe For Pipes and Septic | 4 Gallon Case
- MAIN LINE OPENER: Break down buildup in pipes and get rid of stubborn clogs. This high-density bleach free formula sinks to problem areas and liquefies hair, sludge, flushable wipes and other organic material in your main drain line.
- SAFE FOR ALL PIPES & SEPTIC SYSTEMS: Use it in sinks, tubs, and toilets. It's not harmful to copper or PVC pipes and can even be used in garbage disposals! This bottle also uses anti-glug technology to help reduce splashing.
- POWERFUL REACH: The Main Line Opener will reach clogs up to 50 feet away from the drain. For main line clogs, simply pour it into the first floor toilet, flush, and refrain from use for 10-12 hours.
- BLEACH FREE FORMULA: Green Gobbler uses a powerful bleach free formula and is non-corrosive to plumbing.
- GREEN GOBBLER GUARANTEE: Green Gobbler cares about its customers. We take pride in developing innovative & effective products for your home or business. If for any reason you are unsatisfied, please contact us. We offer a money-back guarantee within 30 days of purchase.
$94.99
Best Eco Friendly Drain Line Cleaner | Main Drain Lines | Sink and Floor Pipes | Sewers | Urinals | Toilets | for use in Residential or Commercial Drains
- WORKS FOR: Bathroom Sinks, Bath Tubs, Showers, Toilets, Kitchen Sinks, Floor Drains, Slop Sinks, Urinals, RV Drains and More
- EFFECTIVE AGAINST: Grease, Hair, Toilet Paper, Soap Scum, Organic Materials, Body Oils, Calcium and Lime Buildup, Rust, Flushable Baby Wipes, Toothpaste, Shampoo Residue, Iron Buildup and More
- SAFER: alternative for picpes compared to toxic and dangerous liquid drain chemicals
- GUARANTEE : We value our customers and we stand behind ALL of our products 100 percent with no questions asked. If you are not pleased simply call or email us with your order number and we will reimburse you in FULL
$78.98
Roebic K-97 Main Line Cleaner, Exclusive Bacteria Digests Paper, Fats, and Grease in Sewer and Septic Systems, 64 Ounces
- PREVENTS CLOGS AND BACKUPS: Roebic K-97-H-3 Main Line Cleaner naturally breaks down waste such as paper, sludge, fats & grease to quickly restore proper flow to your sewer lines or septic system
- SAFE FOR ALL PLUMBING: K-97-H-3 treatment is safe on all pipes for any household and the environment to help keep your lines free of backups
- IDEAL FOR LOW FLOW TOILETS: K-97-H-3 is indispensable in resolving the problems of sludge buildup due to the inefficiencies of "low flow" toilets by keeping the sewer pipe clear
- EASY TO USE: Simply shake well, pour 8 ounces into toilet, and flush (repeat for 4 consecutive days); Repeat four times a year, or as needed
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Drain Cleaning Bladder Unclogs Main Drain&Sewer Line,Water-Powered Clog Cleaner Fits 4 to 6 Inch Pipes Includes Bathroom,Swimming Pool,Basement,Bathtub,Kitchen
- Spec: Drain cleaning bladder fits 4 to 6 inch drain pipes and inflation pressure between 40 and 80 psi
- Unclog blocked drains: The main line sewer drain cleaner is able to cleanup and rise all soil,mud,silt or other blockages along the flow of the drain to keep the drain clear/unclogged and restore the house water supply system.
- Save time&money: No need to call plumber or use traditional clog remover tools, just need the drain cleaning water bladder and a garden hose. Greatly saves a lot of work time and sewer repair costs.
- Working principle: Clear clogged drain bladder is designed to expand inside a pipe, seal the pipe, and provide just enough flow to pressurize the pipe behind the clog. Great for cleaning bathroom / bathtub / kitchen / basement / swimming pool / outside main and sewer drains.
- Easy to use: Just hook the drain bladder to a garden hose and feed it at least 6 inches into the drain. Slowly turn on the cold water until the drain bladder unclogger expands to fit closely the pipe wall and then begins to clean.
$16.59
Last update on 2025-05-01 / Affiliate links / Images from Amazon Product Advertising API