Dandruff shampoos are essential for those struggling with flaky scalp issues, and the market in 2025 offers some of the best options to combat this common problem. From medicated formulas containing zinc pyrithione to natural alternatives infused with tea tree oil, these shampoos cater to various hair types and sensitivities. Whether you're looking for a gentle daily cleanser or a powerful treatment for severe dandruff, the right shampoo can make a significant difference in maintaining a healthy scalp and beautiful hair. Explore the top choices that promise to keep your scalp flake-free and refreshed.
Nizoral Anti-Dandruff Shampoo with 1% Ketoconazole, Fresh Scent, 7 Fl Oz
- Clinically Proven: Clinically proven to control flaking, scaling and itching from dandruff. Nizoral is so powerful it can even control severe dandruff.
- Controls Scalp Fungus: Nizoral is different because it doesn’t just address the symptoms, it gets right to the root of dandruff as it kills the fungus that causes it.
- Ketoconazole 1%: The only over the counter dandruff shampoo with Ketoconazole 1%, a clinically proven, powerful dandruff fighting ingredient.
- 10X More Effective: The active ingredient in Nizoral is 10X more effective at killing scalp fungus, the primary cause of dandruff, than the active ingredient in the leading dandruff shampoo based on lab testing (not a product to product comparison)
- Gentle On Hair: Gentle enough to use on color treated, chemically processed, or gray hair. Clean fresh scent and you only have to use it 2x per week.
$15.88
SALE
−$2.02
CeraVe Hydrating Anti Dandruff Shampoo, 1% Pyrithione Zinc Dandruff Treatment With Ceramides, Niacinamide & Hyaluronic Acid, Helps Eliminate Flakes & Provides Itchy Scalp Relief, Sulfate Free, 12 Oz
- [ HELPS ELIMINATE DANDRUFF SYMPTOMS ] Experience up to 100% flake removal* with 1% Pyrithione Zinc shampoo for dandruff, effectively reducing itchy scalp and irritation for a comfortable, healthy-looking scalp. *when regularly used as a system
- [ CARES FOR THE SCALP BARRIER ] Medicated shampoo formulated with three essential ceramides, niacinamide, and hyaluronic acid, this shampoo helps with symptoms of dandruff like itchiness without disrupting your scalp's barrier, helps remove buildup.
- [ SOFT & NOURISHING ] Pair this anti-dandruff shampoo with CeraVe Anti-Dandruff Conditioner for hair that feels soft and nourished, enhancing both scalp health and hair texture with regular use. Shampoo helps relieve itchy scalp.
- [ DEVELOPED WITH DERMATOLOGISTS ] This dandruff shampoo is pH-balanced & allergy-tested, suitable for color treated hair, sensitive scalps, and is free from sulfates, MIT, dyes, parabens, and fragrances.
- [ SUITABLE FOR ALL HAIR TYPES ] This sulfate free dandruff shampoo is suitable and effective for all hair types and curl patterns, including color-treated hair. Anti dandruff shampoo for men and women.
$9.97
Nizoral Anti-Dandruff Shampoo with 1% Ketoconazole, Fresh Scent, 14 Fl Oz
- Clinically Proven: Clinically proven to control flaking, scaling and itching from dandruff. Nizoral is so powerful it can even control severe dandruff.
- Controls Scalp Fungus: Nizoral is different because it doesn’t just address the symptoms, it gets right to the root of dandruff as it kills the fungus that causes it.
- Ketoconazole 1%: The only over the counter dandruff shampoo with Ketoconazole 1%, a clinically proven, powerful dandruff fighting ingredient.
- 10X More Effective: The active ingredient in Nizoral is 10X more effective at killing scalp fungus, the primary cause of dandruff, than the active ingredient in the leading dandruff shampoo based on lab testing (not a product to product comparison)
- Gentle On Hair: Gentle enough to use on color treated, chemically processed, or gray hair. Clean fresh scent and you only have to use it 2x per week.
$27.99
SALE
−$1.17
Selsun Blue Medicated Antidandruff Shampoo, Maximum Strength Scalp Treatment With Selenium Sulfide, 11 fl. oz.
- Contains one (1) 11-fluid-ounce bottle of Selsun Blue Medicated Antidandruff Shampoo
- New cleaner formula designed to leave hair soft and silky
- Maximum strength antidandruff shampoo without a prescription, made with 1% selenium sulfide
- Helps prevent and eliminate itching, irritation, flaking, redness, and scaling of the scalp
- The quick-lather formula deeply cleans your hair; the cooling menthol intensively moisturizes to provide soothing relief for your scalp
$7.92
Neutrogena T/Sal Therapeutic Shampoo for Scalp Build-Up Control with Salicylic Acid, Scalp Treatment for Dandruff, Scalp Psoriasis & Seborrheic Dermatitis Relief, 4.5 fl. oz
- This effective dandruff shampoo contains 3% salicylic acid, a clinically proven active ingredient and treats symptoms caused by scalp psoriasis, seborrheic dermatitis & dandruff
- This therapeutic shampoo continues to work for hours even after shampoo is rinsed off with a conditioning formula free of added color, preservatives & fragrance
- Dermatologist-recommended dandruff shampoo provides maximum relief for dry, itchy, flaky scalps
- After just one use, this effective salicylic acid shampoo starts clearing crusty scalp build-up while relieving itching and flaking associated with severe scalp conditions
- Treat scalp build-up with Neutrogena T/Sal Therapeutic Shampoo Scalp Build-Up Control.
$7.32
SALE
−$1.97
Amazon Basics Dandruff Shampoo for Normal to Oily Hair, 28.2 Fluid Ounces, 1 Pack
- DANDRUFF CONTROL: This anti dandruff shampoo for men and women helps control itching and flaking associated with dandruff
- GENTLE AND PH BALANCED: Designed for everyday use, this anti dandruff shampoo is gentle and pH balanced, making it suitable for normal to oily hair types
- FREE FROM PARABENS AND PHTHALATES: This anti dandruff shampoo for women and men is formulated without parabens and phthalates
- CLEAN SCENT: Enjoy the clean scent that accompanies every wash with our dry scalp shampoo.
- NOT TESTED ON ANIMALS: This itchy scalp shampoo is not tested on animals and is proudly made in the U.S.A with U.S. and foreign components
$8.77
Selsun Blue Moisturizing Antidandruff Shampoo, Maximum Strength Scalp Treatment With Selenium Sulfide, 11 fl. oz.
- Contains one (1) 11-fluid-ounce bottle of Selsun Blue Moisturizing Antidandruff Shampoo
- New cleaner formula* designed to leave hair soft and silky
- Maximum strength antidandruff shampoo without a prescription, made with 1% selenium sulfide
- Helps prevent and eliminate itching, irritation, flaking, redness, and scaling of the scalp**
- The quick-lather formula deeply cleans your hair; the nourishing aloe intensively moisturizes to provide soothing relief for your scalp
$14.74
SALE
−$2.02
CeraVe 2 In 1 Hydrating Anti Dandruff Shampoo And Conditioner, 1% Pyrithione Zinc Dandruff Treatment, Color Safe & Sulfate Free Shampoo And Conditioner, Helps Eliminate Dandruff & Relieve Itchy Scalp
- [ HELPS ELIMINATE DANDRUFF ] 2 in 1 shampoo and conditioner contains 1% Pyrithione Zinc, effectively removing up to 100% of visible flakes and provides itchy scalp relief while reducing irritation, with regular use.
- [ MEDICATED SHAMPOO AND CONDITIONER 2 in 1 ] This dandruff scalp treatment removes buildup without stripping away moisture. It contains 3 skin identical ceramides, niacinamide, and hyaluronic acid to support the scalp & hair.
- [ CARES FOR THE SCALP BARRIER ] After use, hair feels noticeably healthy and soft, enhancing overall hair texture and appearance. This hair treatment is gentle on dry scalp & hair. Color safe shampoo and conditioner.
- [ DEVELOPED WITH DERMATOLOGISTS ] pH balanced and allergy tested, this product is suitable for sensitive scalps. Sulfate free 2in1 shampoo and conditioner, while also being free of MIT, dyes, parabens, and fragrance.
- [ SUITABLE FOR ALL HAIR TYPES ] This itchy scalp shampoo & conditioner is versatile, accommodating all hair types, curl patterns, and those with color-treated hair. Anti dandruff shampoo for men and women.
$9.97
Dove Damage Therapy Derma Shampoo Dryness + Itch for Flaky Scalp with Pyrithione Zinc and Coconut Oil 12 Fl Oz
- MOISTURIZED FLAKE-FREE HAIR: Dove Dryness & Itch Shampoo and Conditioner system nourishes your hair from root to tip for smooth, soft hair and cares for your irritated scalp
- SHAMPOO FOR FLAKY SCALP: Try this Dove hair shampoo with coconut oil for 100% flake-free hair* *no visible flakes with regular use
- ACTIVE PYRITHIONE ZINC FORMULA: Pyrithione Zinc tackles dandruff, maintaining hair's moisture balance without stripping away essential nutrients in this anti dandruff shampoo
- HOW TO USE: Apply Dove Dryness & Itch shampoo to wet hair, lather and rinse before using Dove Derma Dryness & Itch conditioner
- BACKED BY SCIENCE: This hair repair shampoo uses Dove technology that’s backed by 10 years of research. Protecting, repairing, and restoring hair to reduce signs of damage
$4.84
Head & Shoulders Clinical Strength Dandruff Shampoo, Selenium Sulfide Dandruff Defense, Intensive Itch Relief, Seborrheic Dermatitis Relief, Cooling Menthol, 13.5 Fl Oz Each, 2 Pack
- INTENSIVE ITCH RELIEF: 35% more dandruff fighting power* *fights Malassezia after 1 wash vs ordinary anti-dandruff shampoos
- PRESCRIPTION STRENGH*: Made with 1% Selenium Sulfide for prescription strength* dandruff relief and flaking protection *flake protection vs prescription dandruff shampoo 2% ketoconazole
- CLINICALLY PROVEN: Up to 100% dandruff protection* *visible flakes; with regular use
- EXTRA STRENGTH: Provides relief from severe dandruff and seborrheic dermatitis
- MULTI-SYMPTOM RELIEF: Offers proven protection from flakes and itch* *Flakes and itch associated with dandruff
$23.94
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API