Best cream for psoriasis over the counter options are essential for managing the discomfort and visibility of this chronic skin condition. In 2025, several effective creams have emerged that provide relief from itching, redness, and scaling. These products often contain active ingredients like salicylic acid, coal tar, or hydrocortisone, which help to soothe the skin and reduce inflammation. When selecting a cream, it's important to consider your skin type and the severity of your symptoms to find the most suitable treatment.
Psoriasin Deep Moisturizing Ointment - 2% Coal Tar - Stops Psoriasis Itching, Scaling, Redness - 4.2 oz
- Relieve psoriasis symptoms: Psoriasin Deep Moisturizing Ointment stops psoriasis itching, scaling, & redness and helps prevent recurrence
- Soothe & protect: The rich Psoriasin Ointment formula soothes, penetrates, & locks in moisture to provide prompt flare-up control and is a reliable cortisone alternative
- Psoriasis support: The coal tar in Psoriasin products is the only FDA compliant, non-prescription drug ingredient that slows excessive skin cell production – the root cause of psoriasis symptoms
- Leading producer: Alva-Amco is a leading U.S. Producer of specialty non-prescription pharmaceuticals, dietary supplements, and skin care products. Alva-Amco has a history of product innovation, quality & consumer Satisfaction in over the counter products
$13.09
SALE
−$2.17
MG217 Multi Symptom Relief 2% Coal Tar Medicated Psoriasis Ointment oz Jar, 4 Oz
- One 4 oz jar of MG217 Psoriasis Multi Symptom Relief 2% Coal Tar Medicated Ointment
- MG217 Coal Tar psoriasis treatment is made to help slow cell overgrowth, and like a Vitamin D ointment it helps prevent symptom recurrence and offers relief
- Relieve itching, redness, and flaky skin. MG217 Coal tar ointment also includes Vitamin A, a key ingredient found in Vitamin A & D ointment
- Restore skin's healthy appearance and fight seborrheic dermatitis with this coal tar ointment
- Seborrheic dermatitis ointment designed to retain skin's natural moisture
$12.82
Keralyt 5 Psoriasis Cream - Full Body 5% Salicylic Acid Exfoliating Skin Lotion - Promotes Relief from Itchy, Redness, Dryness, Roughness, and Flakey Skin
- KERALYT 5: Our maximum strength 5 percent beta hydroxyacid (salicylic acid) cream delivers fast exfoliating relief and helps improve conditions that cause rough and problematic skin over time. Start fighting back with the best!
- THE RELIEF YOU NEED: This moisturizing exfoliating cream helps eliminate problem flaky itchy skin by providing healing relief and helping to exfoliate away redness, roughness, thick scales, plaque, and hyperkeratotic skin.
- HEALING ACTION: With regular use, Keralyt 5 not only helps relieve the symptoms of, but will help address the causes of, conditions like psoriasis, dermatitis, and eczema. Renew your skin for faster, more effective relief.
- EASY TO USE: Keralyt 5 is a topical cream made to be applied externally on the skin all over the body. It's an especially effective moisturizer after bathing as it helps to seal in the moisture. Use it on any problem areas where you're experiencing discomfort.
- SUMMERS LABORATORIES: We take time and care to create solutions that are more than just effective in the short term, we create lotions, creams, ointments, and gels that give long-term support and help you live a better more comfortable life.
$29.49
Kenkoderm Psoriasis Moisturizing Cream - 10 oz | 1 Jar | Dermatologist Developed | Fragrance + Color Free (1 Jar)
- REDUCES FLAKING, ITCHING, SCALING: Kenkoderm 2% Salicylic Acid Moisturizing Cream relieves the symptoms of psoriasis and helps prevent recurrence
- SOOTHES AND MOISTURIZES: A hydrating blend of shea butter and meadowfoam seed oil helps soften and soothe rough patches while repairing the natural epidermal barrier
- FRAGRANCE + COLOR FREE: This cream is made without harsh fragrances or colorants that can irritate sensitive skin
- DERMATOLOGIST DEVELOPED: Kenkoderm was developed and formulated by a dermatologist whose husband developed serious psoriasis flares
- FOR BEST RESULTS: Apply Kenkoderm Cream to affected areas one to four times daily, specifically after showering. Works best when paired with Kenkoderm Dead Sea Mud and Mineral Salt soaps
$24.99
Wild Naturals Eczema & Psoriasis Cream for Dry, Itchy Skin – Eczema Relief Cream for Adults & Kids – Moisturizing Psoriasis Cream with Manuka Honey
- Soothe, Hydrate, & Nourish: Wild Naturals eczema relief & psoriasis cream penetrates deeply to deliver a powerful boost of hydration and nourishment, leaving skin balanced and healthy. This psoriasis lotion & eczema honey cream is specially formulated with soothing & hydrating aloe vera as its base ingredient, not water like most skincare products.
- Protects & Moisturizes Dry, Damaged Skin: Our seborrheic dermatitis itch relief cream & eczema body lotion are enriched with powerful manuka honey from New Zealand. Packed with a unique blend of vitamins, minerals, & amino acids from UMF 12+ manuka honey, this itchy skin relief lotion for eczema & dermatitis cream naturally seals in moisture to protect & restore dry, damaged skin.
- Safe, Gentle, & pH-Balanced Formula: This eczema face cream & anti-itch lotion is perfectly pH-balanced at 5.5 to mimic your skin’s natural pH level, which means it will be easily absorbed without irritating your skin. Our baby eczema lotion & seborrheic dermatitis cream is gentle for all skin types, even for those with very sensitive skin. No harsh & filler ingredients. 100% steroid-free!
- Lightweight & Non-Greasy: Our eczema relief cream provides fast-acting relief for your face, body, hands, feet, or scalp. Our eczema cream soaks right in, leaving your skin feeling nourished & rejuvenated. No petroleum ingredients. Free of parabens, gluten, dyes, & artificial colors. Cruelty-free & 100% made in the USA!
- Our products are carefully formulated using the finest ingredients. We understand that your skin deserves nothing but the best, & we strive to deliver just that.
$23.95
TriDerma Psoriasis Control Face & Body Cream - Maximum Strength 3% Salicylic Acid, AP4 Aloe Vera Gel, Urea Cream - Extra Moisturizing Treatment, No Cortisone or Coal Tar - FSA Eligible - 4.2 oz, 4Pack
- Quality You Can Feel, Results You Can See - Obtain rapid relief with TriDerma Psoriasis Cream for the Face and Body. Recognized by the National Psoriasis Foundation, this powerful, fast-acting anti itch cream is an otc (over-the-counter) first aid cream, safe for sensitive skin health care products.
- Comprehensive Head to Toe Care - Moisturizing cream relieves rapidly. Try itchy hair care salicylic acid shampoo, dry scalp treatment conditioner, body moisturizers & body wash for optimal results.
- Maximum Strength Medicated Cream Hydration - Features potent blend of 3% Salicylic Acid, AP4 Aloe Vera Complex, Urea, Colloidal Oatmeal, & Vitamins B & E, our psoriasis body cream helps skin healing.
- Dermatologist-Tested for Gentle Care - Enjoy the benefits of a paraben, cortizone and coal tar-free non-greasy formula for psoriasis and seborrheic dermatitis made of fresh botanical ingredients.
- Thoughtfully Crafted - Proprietary formula of aloe, harnesses its healing elements. Boasting 200+ beneficial compounds, it's stronger than typical psoriasis lotion extra strength or cortisone cream.
$39.97
SALE
−$5.00
Dermeleve Steroid Free Anti-Itch Cream | Extra Strength for Psoriasis, Seborrheic Dermatitis, Viral Rash, Bug Bites, Allergy, Chronic Hives, Neuropathy (Nerve) | Full Body Itch Relief | 120g (1 Pack)
- STEROID-FREE ANTI-ITCH CREAM: Dermeleve is a next-generation OTC itchy skin relief cream formulated specifically to deliver safe, maximum strength results—even for sensitive body parts, intimate areas, and thinning skin. Suitable for all unbroken skin, it provides effective, fast itch relief.
- STOPS 3 TYPES OF ITCH in minutes (1) Hard to treat chronic and senior itch that has lasted 6 weeks or more (2) Itch without a rash (3) Allergic itch, such as Hives, Insect Bites & Stings, and Contact Dermatitis.
- SOOTHES DRY, IRRITATED SKIN with SrX-38, Ceramides, Hyaluronic Acid, and Vitamins C & E. Our non-steroid itchy skin lotion moisturizes and nourishes painful skin, promoting skin barrier repair and enhancing the skin's natural resilience against further irritation.
- NON-GREASY, REAPPLY AS NEEDED: This gentle, yet highly effective, anti-itch lotion absorbs quickly and won't make your skin greasy. Free of fragrances, corticosteroids, formaldehyde, parabens, and skin-clogging ingredients. Hypoallergenic, non-toxic and safe for non-broken skin of all types.
- DEVELOPED & TRUSTED BY DERMATOLOGISTS across the United States. Dermeleve anti-itch cream is manufactured by Advanced Derm Solutions, a science and solutions focused company based in Tampa, Florida.
$34.99
MG217 Medicated Moisturizing Psoriasis Cream With 3% Salicylic Acid, Multi-symptom, Fragrance Free, 3.5 Fl Oz, (5604)
- Medicated skin cream controls flaking and helps prevent psoriasis and seborrheic dermatitis symptom recurrence in a soothing moisturizing cream for dry skin
- Moisturizing skin cream is a salicylic acid psoriasis treatment that has Provitamin B5, Avocado oil, Shea butter, Bisabolol, Aloe, Vitamin E, Allantoin and Panthenol
- Number of items: 1.0
- Safety warning: For external use only
$13.42
Psoriasin Multi-Symptom Psoriasis Relief Ointment, 4 Ounce
- Multi-symptom psoriasis relief
- Helps relieve itching, flaking, redness, scaling, and discomfort
- Calms even the most intense symptoms
- Helps prevent future flare-ups
- Contains coal tar which slows down exessive skin cell production that is the root cause of psoriasis symptoms
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Max Strength Bee Venom Cream, Natural Organic Soothing Treatment for Psoriasis, Rash, Jock Itch, Stubborn Ringworm, Itchy, Dry Skin - All Body Skin for Children & Adults
- Soothing care for all ages: Experience fast comfort for dry, sensitive or itchy skin with our Bee Venom Cream. Ideal for eczema and psoriasis, it's made with gentle, natural ingredients to maintain moisture and is free from parabens, sulphates and artificial fragrances.
- Hydrating and nourishing formula: Enriched with beeswax and organic honey, our cream is suitable for all ages and can be applied to different parts of the body. It deeply moisturises and promotes skin with the ultra-soothing properties of Manuka Honey, helping to manage symptoms of eczema, psoriasis, rosacea and acne.
- Holistic skincare solution: Embrace holistic skincare with our premium cream. Formulated with Colloidal Oatmeal and Arnica Montana Flower Extract, it absorbs quickly to leave skin smooth and nourished and is suitable for the whole family including babies, children, teenagers, men and women.
- Conscientious and vegan: Carefully crafted, our cream is vegan, cruelty free and made with sustainably sourced ingredients. A 5-minute daily routine hydrates, moisturises and nourishes skin with no strings attached to keep it healthy and vibrant.
- Quality you can trust: Made from New Zealand's family-grown Manuka Honey and proudly made in the UK, our ointment is lightweight, fast-absorbing and gentle on sensitive skin.
$15.99
Last update on 2025-05-03 / Affiliate links / Images from Amazon Product Advertising API