Cold sore cream is essential for anyone looking to alleviate the discomfort and speed up the healing process of cold sores. In 2025, the market offers a variety of effective options that cater to different needs, from over-the-counter treatments to prescription-strength formulas. These creams not only help reduce pain and itching but also promote faster recovery. Whether you prefer natural ingredients or advanced antiviral compounds, there’s a cold sore cream that can suit your preferences and lifestyle.
SALE
−$9.23
Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Tube x 2
- Number 1 Cold Sore Brand: Two 0.07 oz tubes of Abreva 10 Percent Docosanol Cold Sore Treatment
- Can Heal in 2.5 Days: Fever blister cream contains 10 percent docosanol to shorten the duration of cold sore symptoms (1)
- Nothing Heals Fever Blisters Faster: 10 percent docosanol cream penetrates deep into skin to tackle cold sores at their source (1, 2, 3)
- Lip Cream Clinically Proven to Shorten Duration of Symptoms: Cold sore product shortens duration of tingling, pain, burning and itching associated with cold sores (1)
- Portable Cold Sore Cream: Packaged in a convenient tube for on the go cold sore treatment
$25.00
SALE
−$4.75
Campho Phenique Cold Sore and Fever Blister Treatment for Lips, Maximum Strength Provides Instant Relief, Helps Prevent Infection To Promote Healing, Original Gel Formula, 0.23 Oz
- Trusted: A favorite for cold sore and fever blister treatment for lips for over 130 years.
- Instant Relief: Formulated with camphor and phenol to temporarily inactivate the pain signals at the nerve endings in the skin to provide a local anesthetic (numbing effect) that stops the pain and itch of cold sores and fever blisters on contact.
- Helps Prevent Infection: Antiseptic properties help prevent infection to promote cold sore healing.
- Aloe Soothes and Moisturizes: Prevents dryness and cracking as cold sores and fever blisters dry out.
- Store at room temperature
$4.24
Abreva Cold Sore Treatment Rapid Pain Relief Cream - 1 Tube, 3 Grams
- One tube of Abreva Cold Sore Rapid Pain Relief, 3 grams.
- Shortens duration of tingling, pain, burning and itching
- Easy applicable tube form for on-the-go use
- When you feel pain and burning from the cold sore or blister, Abreva has you covered with Abreva Rapid Pain Relief gel
- It delivers quick, targeted relief from the first application
$12.47
TARO Cold Sore/Fever Blister Treatment - Docosanol 10% Cream (0.07 oz - 2 Tube)
- Docosanol Cream 10% – Treats cold sores/fever blisters
- Treats Cold Sores / Fever Blisters on the Face or Lips
- Shortens Healing Time and duration of Symptoms
$14.99
SALE
−$2.51
Quantum Health Lip Clear Lysine+ Cold Sore Treatment Soothe & Moisturize Mouth Sores - L-Lysine Menthol Calendula & Propolis Ointment - Transparent Fever Blister Healing Balm - 0.25 Oz
- HALVE YOUR HEALING TIME - Cut cold sore healing time by 50% with the power of L-Lysine, a scientifically researched amino acid that inhibits arginine activity, nourishes skin and accelerates recovery.
- FAST-ACTING PAIN & ITCH RELIEF - Experience rapid relief from cold sore pain, burning, and itching discomfort with the cooling effect of Menthol plus 14 herbal ingredients to soothe and nourish your skin.
- HERBAL LIP TREATMENT - Harness the power of our nutrient-rich formula with Calendula, Vitamin E, and Propolis, providing deep moisturization and skin-nourishing properties for overall lip health.
- DISCREET COMFORT - Invisible balm can be worn under lipstick or gloss without worry, doesn't burn upon application, and offers relief from tingling, itching, burning, and other discomforts associated with cold sores.
- ROUND OUT YOUR LIP CARE ROUTINE - For optimal results use Lysine+ Ointment with our Super Lysine Immune Support Tablets and Lip Clear Invisible Cold Sore Patch to calm cold sores and promote faster healing.
$7.48
Wellness Basics Docosanol Cream 10% | Cold Sore Treatment | Shortens Healing Time | 0.07oz - 1 Tube
- DOCOSANOL CREAM 10% – Treats cold sores/fever blisters on face or lips. Shorten healing time and duration of cold sore symptoms.
- APPLY AT FIRST SIGNS - Tackle cold sores head on. Use at first signs of symptoms such as tingling, burning, or itching for a faster recovery. Early treatment ensures best results.
- SHORTEN HEALING TIME – This non-prescription cold sore medicine can be used five times a day until the cold sore is healed.
- HELP ON THE GO – Convenient sized packaging means you can treat cold sores on the go. Single Pack comes with 1 Tube.
- Compare to the Active Ingredient in leading national brand
$8.97
TARO Cold Sore/Fever Blister Treatment - Docosanol 10% Cream (0.07 oz - 1 Tube)
- Docosanol Cream 10% – Treats cold sores/fever blisters
- Treats Cold Sores / Fever Blisters on the Face or Lips
- Shortens Healing Time and duration of Symptoms
$8.99
Last update on 2025-05-03 / Affiliate links / Images from Amazon Product Advertising API