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10 Best cold medicine for stuffy nose (2025) - Joe's Italian Restaurant & Pizza

10 Best cold medicine for stuffy nose (2025)

Cold medicine for stuffy nose can provide much-needed relief during the winter months when congestion strikes. The best options on the market combine decongestants, antihistamines, and soothing ingredients to help clear nasal passages and ease discomfort. Popular choices include formulations with phenylephrine and pseudoephedrine, which effectively reduce swelling in the nasal passages. Additionally, some products offer added benefits like cough suppression and pain relief, making them versatile for cold symptoms. When selecting the right cold medicine, consider your specific symptoms and any underlying health conditions to ensure the best results.

SALE −$2.52

Vicks Sinex SEVERE Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Stuffy Nose due to Cold or Allergy, & Nasal Congestion, Sinus Pressure Relief, 265 Sprays x 2

  • Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses
  • Breathe better all day or all night long with Vicks Sinex Severe. For instant, 12-hour, nasal congestion and sinus pressure relief
  • This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell, Not intended for daily use
  • Unlike nasal decongestant tablets, Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes
  • Vicks Sinex Severe Nasal Spray is HSA and FSA eligible, Check with your provider for more details

$14.97

Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays

  • Targets nasal congestion and sinus pressure at the source by reducing swelling in the sinuses
  • Breathe better all day or all night long with Vicks Sinex Severe. For instant, 12-hour, nasal congestion and sinus pressure relief
  • This powerful decongestant medicine be used to treat severe sinus congestion and pressure caused by a cold or seasonal allergy spell, Not intended for daily use
  • Unlike nasal decongestant tablets, Vicks Sinex Severe Nasal Sprays works by delivering powerful decongestant medicine directly to your nasal membranes
  • Vicks Sinex Severe Nasal Spray is HSA and FSA eligible, Check with your provider for more details
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$10.46
SALE −$3.02

Mucinex Sinus Max Severe Congestion & Pain Relief, Maximum Strength Nasal & Sinus Relief, Decongestant for Adults, Acetaminophen Pain Reliever, Guaifenesin Expectorant and Mucus Removal, 20 Caplets

  • MAXIMUM STRENGTH RELIEF: Maximum Strength Mucinex Sinus-Max Severe Congestion & Pain helps relieve pain, headache, nasal congestion, sinus congestion and chest congestion.
  • #1 TRUSTED COLD AND COUGH BRAND: #1 Cold and Cough brand doctors trust*
  • PAIN RELIEVER: Contains Acetaminophen which relieves minor aches and pains
  • EXPECTORANT: Contains Guaifenesin that thins and loosens mucus; relieves chest congestion
  • NASAL DECONGESTANT: Contains Phenylephrine HCl that provides relief for nasal congestion, sinus congestion and pressure

$10.97
SALE −$3.02

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

  • RELIEF YOU TRUST, DAY & NIGHT. Use non-drowsy DayQuil SEVERE for daytime relief and at night try NyQuil SEVERE for fast relief so you can rest.
  • POWERFUL COLD & FLU RELIEF. DayQuil and NyQuil SEVERE temporarily relieve common cold & flu symptoms
  • NOTHING WORKS FASTER. Just one dose starts working fast to provide effective cold & flu relief
  • PROVEN RELIEF FOR YOUR WORST COLD & FLU SYMPTOMS. Life doesn’t stop when you have a cold. NyQuil and DayQuil SEVERE tackle your most bothersome cold & flu symptom
  • WORLD'S #1 SELLING OTC COUGH AND COLD BRAND. Vicks has been trusted for over 125 years to relieve your worst cold & flu symptoms.

$16.97
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Vicks Sinex SEVERE LiquiCaps, All-In-One Sinus Relief, Non-Drowsy, Nasal Decongestant, Maximum Strength Relief of Sinus Headache, Pain, Pressure, & Congestion, 24 LiquiCaps

  • Experience fast, powerful relief from nasal congestion, sinus pressure, sinus headache, and sinus pain!
  • Best suited to treat sinus symptoms caused by the common cold, hay fever, or other upper respiratory allergies because it reduces pressure in the sinuses and relieves sinus pain!
  • The powerful, non-drowsy nasal decongestant medicine and pain reliever help to provide all in one relief for your sinus symptoms!
  • HSA and FSA eligible, Check with your provider for more details
  • This product is not formulated with an antihistimine allergy medicine and is not intended to treat runny nose, itchy & watery eyes, or sneezing

$9.25
SALE −$7.01

Vicks Sinus Inhaler - Non-Medicated Steam Relief for Allergies, Congestion, Cough & Colds, Facial Steamer, Soothes Nasal & Throat Passages, Use with VapoPads (1 Included), FSA & HSA Eligible

  • Perfect for seasonal allergies, colds and congestion. Warm steam provides temporary symptomatic relief from dryness and irritation caused by colds, seasonal allergies and sinusitis.
  • Easy, targeted, non-medicated steam relief in a quick 5-15 minute treatment. Vicks Personal Sinus Steam Inhaler with variable steam control can be used with tap water and requires no filter.
  • Only Vicks Vaporizers provide extra comfort to soothe nasal passages when used with Vicks VapoPads. Experience the Vicks Difference with non-medicated steam relief.
  • The soft face mask allows for targeted, non-medicated steam relief, while variable steam control allows you to adjust the steam intensity on this personal humidifier.
  • Vicks humidifiers, vaporizers and steam inhalers help you breathe better and sleep more comfortably.

$42.98
SALE −$1.00

Zicam Cold Remedy No-Drip Nasal Spray with Cooling Menthol & Eucalyptus, Homeopathic, Zinc-Free, Pre-Cold Medicine, Shortens Cold Duration, 0.5 Ounce

Hyland's Kids Stuffy Nose and Sinus Tablets, Cold Medicine for Children Ages 2 and up, Headache Relief and Nasal Decongestant, Quick Dissolving Tablets, 50 Count

  • Temporarily relieves symptoms of stuffy nose and sinus in children including: nasal congestion, sinus pressure, and headache
  • Hyland's Kids medicines are made with natural active ingredients, and created especially for kids ages 2 to 12
  • EASY TO TAKE: Quick-dissolving tablets that melt in your mouth almost instantly
  • KEEPING FAMILIES HEALTHY: Hyland’s is a leading consumer health brand with more than a century of history making high quality products to help people live healthier and happier lives.
  • Made in the USA

$10.67

Vicks Sinex Severe Nasal Spray, Moisturizing Ultra Fine Mist with Aloe, Decongestant Medicine, Relief from Stuffy Nose Due to Cold or Allergy, Nasal Congestion & Sinus Pressure Relief, 265 Sprays x 2

  • INSTANT SINUS RELIEF: Vicks Sinex Severe Nasal Spray clears your stuffy nose in seconds and works 6x faster vs. nasal decongestant tablets.
  • LAST 12 HOURS: Breathe freely with powerful sinus and congestion relief day or night
  • WORKS AT THE SOURCE: Targets nasal congestion at the source to help you breathe easier
  • POWERFUL VICKS VAPORS: Vicks vapors provide soothing and comforting relief of your congestion
  • MOISTURIZING: Contains hints of aloe

$17.49

Last update on 2025-05-03 / Affiliate links / Images from Amazon Product Advertising API