Bed bug spray is an essential tool for anyone dealing with these persistent pests. In 2025, the market offers a variety of effective options that cater to different needs, from natural formulations to powerful chemical solutions. The best bed bug sprays not only kill existing bugs but also provide long-lasting protection against future infestations. With user-friendly applications and proven results, these products are a must-have for maintaining a pest-free environment. Whether you're a homeowner or a renter, investing in the right bed bug spray can save you time, money, and stress in the long run.
SALE
−$3.02
Ortho Home Defense Max Bed Bug, Flea and Tick Killer with Comfort Wand, Bed Bug Spray, Kills Bed Bug Eggs, Fleas and Ticks, 1 gal.
- Kill bed bugs, bed bug eggs, fleas and ticks with Ortho Home Defense Max Bed Bug, Flea & Tick Killer
- This bed bug spray kills even the toughest bed bugs (pyrethroid-resistant bed bugs)
- Use this indoor bug killer as a spot treatment around bed frames, baseboards and mattress seams, tufts and folds
- Apply insect spray using the included Comfort Wand to target tight and hard-to-reach places where bed bugs hide
- Ortho Home Defense Max Bed Bug, Flea & Tick Killer is a Step 2 product in the Ortho Bed Bug Solution System; use with Step 1: Detect and Trap and Step 3: Cracks and Crevices products for best results
$19.97
Hot Shot Ready-to-Use Bed Bug Killer Spray, Kills Bed Bugs and Bed Bug Eggs, Kills Fleas and Dust Mites, 32 Ounce
- Bed bug treatment: Hot Shot bed bug Killer with egg kill kills bed bugs and bed bug eggs, adult and pre-adult (larvae) fleas and Dust mites
- Use indoors: spot treat mattress tufts, folds, vent holes, buttons, creases, indentations and seams – do not use on pets
- Water-based formula: this non-staining formula leaves no odor
- Application: spray intended use areas until damp, but do not saturate – inspect the area and apply every two weeks while bed bugs are present
- Treat bed bugs as part of a cycle: for Best results, use this product as part of a comprehensive bed bug treatment plan — treating bed bugs as part of a cycle is key to gaining control
$17.99
Bed Bug Killer 16 oz EcoVenger by EcoRaider, 100% Kill Efficacy, Bedbugs & Mites, Kills Eggs & The Resistant, Lasting Protection, USDA BIO-Certified, Plant Extract Based & Non-Toxic, Child & Pet Safe
- PROVEN THROUGH USDA IR4 PHP PROGRAM — field tested by research entomologists for eradicating bed bug infestations in public housing buildings and recommended for sensitive environment
- KILL ALL STAGES INCLUSIVE & EVEN RESISTANT BED BUGS — Kills bed bug adults and nymphs fast on contact with 100% efficacy, kills bed bugs that are resistant to traditional pesticides. Proven highest performance in eliminating bed bug eggs
- EXTENDED DRY RESIDUAL PROTECTION — University study shows EcoRaider residual provides extended protection for two weeks on bed bugs even after dried
- NON-TOXIC, SAFE AND ECO-FRIENDLY — certified USDA BioBased insecticide, dermatologically safe; child and pet friendly; safe to use directly on mattress and box springs.
- INGREDIENTS: Geraniol, Cedarwood oil, Sodium Lauryl Sulfate, Glyceryl dicaprylate, Silica hydrate, Glyceryl monooleate and water.
$19.45
All Natural Bed Bug Spray - Non-Toxic Bed Bug Killer - 2 Bottle Value Bed Bug Spray Travel Size - Fast-Acting Bed Bug Killer | Kills Fleas and Mites
- Fast-acting bed bug elimination: Our Natural Bed Bug Spray 2-Pack delivers swift and effective treatment against bed bugs, eliminating both adult bugs and their eggs to halt infestations in their tracks.
- Convenient travel size: Each 3 oz bottle is perfectly sized for travel, ensuring you can effectively combat bed bugs wherever you go, whether it's a hotel room, vacation rental, or friend's house.
- Versatile formula: In addition to targeting bed bugs, our spray also tackles other pests like fleas and dust mites, providing comprehensive protection for your bedding and surrounding areas.
- Trusted bed bug treatment: Harnessing the power of natural ingredients, our bed bug spray offers a safe and eco-friendly solution for getting rid of bed bugs permanently, without the need for harsh chemicals or pesticides.
- Compatible with other treatments: Whether used alone or in conjunction with products like Crossfire bed bug concentrate or Cimexa bed bug killer, our spray enhances the effectiveness of your bed bug treatment regimen, ensuring thorough eradication of these pesky pests.
$9.99
SALE
−$0.73
Raid Bed Bug Foaming Spray, Kills Bed Bugs and Their Eggs, for Indoor Use, Non-Staining, Keeps Killing for Weeks, 16.5 oz (Pack of 1)
- Kills bed bugs and their eggs on contact
- Kills bed bugs on surfaces for up to 4 weeks
- Foam expands into hard to reach indoor places, and is easy to see where you sprayed
- Scientifically formulated to kill Pyrethroid-resistant Bed Bug strains
- Money Back Guarantee
$10.25
SALE
−$5.00
Eco Defense Bed Bug Killer - Bed Bug Spray & Dust Mite Spray - Natural Treatment - 16 oz
- KILLS ON CONTACT - Natural ingredients eliminate bed bugs on contact in all stages of life, Eggs, Nymphs, and Adults.
- NON STAINING - Won't stain your bedding like some products on the market. Apply directly to sheets, mattress and cover to kill bed bugs on site.
- SLEEP SECURE - Made of natural as well as plant-based ingredients. No worries of fumes or dangerous pesticides and chemicals coming in contact with you and your family
- FASTEST TREATMENT - Eco Defense Bed Bug Killer Spray works extremely fast and is easy to use. Many customers have found it easier to use and more effective than other Bed Bug products including, Bed Bug Powders, Bed Bug Traps, and Bed Bug Foggers. Rest assured, Eco Defense is your #1 solution.
$19.95
SALE
−$13.04
MGK Crossfire® Bed Bug Concentrate | Kills Pyrethroid-Resistant Bed Bug Strains | 13 oz | Non-Staining
- PATENTED FORMULA: CrossFire bed bug spray kills pyrethroid-resistant bed bug strains at all life stages, including eggs. With its two active ingredients and a synergist, get effective bed bug control.
- QUICK KNOCKDOWN AND KILL: Begins working within minutes of exposure. This professional product is backed by multiple active ingredients.
- NON-STAINING: For indoor use in residential, institutional and commercial facilities, this bed bugs killer treatment is approved for direct application onto mattresses.
- EASY TO MIX AND USE: One 13-ounce bottle of bed bug concentrate makes one gallon of finished product.
- A LEGACY YOU CAN TRUST: Driven by expertise and industry commitment, MGK has been developing pest control products based primarily on botanical and innovative technologies since 1902.
$36.96
HARRIS White Label Bed Bug Killer, Liquid Spray with Odorless and Non-Staining Extended Residual Kill Formula (32oz)
- Kills Resistant Bed Bugs and Their Eggs - Kills even the toughest "pyrethroid resistant" bed bugs and eggs that have built up a resistant to traditional pesticides
- Kills Quickly - Knocks down bed bugs fast when sprayed directly
- EPA Registered - Approved for use in homes with people and pets by the Environmental Protection Agency (1021-2597-3). Always follow label directions
- Long Residual - Continues to kill bed bugs for up to 16 weeks after initial application
- Odorless Formula - Odorless and non-staining formula will not cause damage to fabrics when used according to label directions
$19.99
SALE
−$4.29
BASF PT Alpine Flea & Bed Bug Killer, Fast Acting Insecticide, Extended Long Lasting Pest Control Formula, Quick Dry, Non-staining, Ready to Use Spray Can 14 oz
- Quick Results: Fast knockdown of bed bugs and fleas, providing fast relief and long-lasting protection; Treat room perimeter at the wall-floor junction; behind, under and inside furniture; on headboards and box springs; mattress edges, tufts, folds, sides and seams; over open carpeted areas and wall coverings; Even treat luggage by directly spraying into pockets, seams, folds and around wheels
- Long-lasting Control: Lasting effectiveness on multiple surfaces for up to 3 weeks; Aids in preventing bed bug hatch; Dual active ingredients target hatching eggs for up to seven months and provides fast knockdown of flea populations
- Reduced Risk Active Ingredient: Dinotefuran, approved for public health use and food handling establishments; Won’t soak carpets or mattresses, dries rapidly and non-staining; Tested and proven to be safe for use in multiple environments
- Easy to Use: The premixed, ready-to-use aerosol spray can be directly used on mattresses and in suspected areas of infestation, making it easy to apply in Apartments, Commercial Structures, Homes, Hotels, Kennels, Motels, and Veterinary Clinics; safe for use around people and pets as instructed; Refer to product label for complete list; Treats up to 2,625 sqft
- Always read, understand and follow label safety and application instructions; For use as intended; State restrictions may applyDO NOT apply to entire mattress; apply only to edges, tufts, folds, sides and seams
$22.71
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API