Antiperspirant is an essential product for those seeking to stay fresh and dry throughout the day. In 2025, the market offers a variety of top-rated options that cater to different skin types and preferences. From clinical-strength formulas to natural alternatives, the best antiperspirants provide long-lasting protection against sweat and odor while ensuring comfort and skin health. Whether you prefer a stick, roll-on, or spray, there’s an ideal choice for everyone. Discover the leading products that have garnered rave reviews and are trusted by consumers worldwide.
Certain Dri Prescription Strength Clinical Antiperspirant Roll-On Deodorant, Hyperhidrosis Treatment for Men & Women, Long-Lasting 72hr Protection, Effective Sweat Control, Fragrance Free, 1.2 Fl oz
- #1 Doctor Recommended: The leading clinical antiperspirant brand recommended by doctors for effectively managing excessive sweating and hyperhidrosis.
- Prescription Strength Formula: Contains a potent antiperspirant ingredient that provides prescription-strength sweat protection without needing a prescription.
- Fragrance-Free Roll-On: Unscented deodorant in a convenient roll-on format, powered by 15% Aluminum Chloride for up to 72 hours of reliable odor and perspiration control.
- Application Instructions: Apply at night to completely dry underarms for optimal results. Reapply in the morning for enhanced freshness and continued protection throughout the day.
- Important Usage Notes: This antiperspirant is highly concentrated and should be applied sparingly to dry skin at night. Avoid using on wet or irritated skin, and refrain from applying immediately after showering or shaving to prevent potential irritation.
$6.99
SALE
−$1.11
Degree Men UltraClear Antiperspirant Deodorant Black+White 2 Count 72-Hour Sweat & Odor Protection Antiperspirant For Men With MotionSense Technology 2.7 oz
- WHITE SHIRT, BLACK SHIRT, NO PROBLEM: Degree UltraClear Black+White Antiperspirant Deodorant delivers 72-hour sweat and odor protection with anti-white marks and anti-yellow stains technology
- YOU MOVE, IT WORKS: Our breakthrough MotionSense technology works in sync with your body all day long. This deodorant for men releases a subtle burst of fragrance every time you move
- DRESS WITH CONFIDENCE: This antiperspirant for men is made with anti-mark and anti-stain technology that protects your clothes from deodorant stains
- INVIGORATING SCENT: Degree Men UltraClear Black+White Antiperspirant Deodorant keeps you feeling fresh all day with a warm, woody scent
- RECYCLE WITH DEGREE: As well as increasing our use of reusable materials, we’re making it easier for you to recycle our antiperspirant and dry spray packaging
$7.98
SALE
−$13.03
Degree Men Original Antiperspirant Deodorant Cool Rush Twin Pack 48-Hour Sweat & Odor Protection Antiperspirant For Men 2.7 oz
- 48-HOUR PROTECTION: Active lives need Degree Men Cool Rush Antiperspirant Deodorant. This antiperspirant for men delivers confidence with 48-hour sweat and odor protection.
- FEEL SHOWER-FRESH ALL DAY: This antiperspirant deodorant keeps you feeling dry with a crisp, arctic scent. You'll feel as fresh as when you started your day.
- READY FOR WHAT’S NEXT: Take on the day with Degree Men Cool Rush Antiperspirant Deodorant stick. Simply twist, glide, and move.
- CRISP SCENT: Stay fresh longer with this antiperspirant for men. Degree Men Cool Rush Antiperspirant Deodorant features a clean, refreshing scent to keep you feeling energized.
- RECYCLE WITH DEGREE: As well as increasing our use of reusable materials, we’re making it easier for you to recycle our antiperspirant and dry spray packaging.
$6.96
SALE
−$4.21
Dove Men + Care Antiperspirant Deodorant, 72hr Sweat & Odor Protection, Vitamin E, Triple Moisturizer, 4 Pack
- 72H UNCOMPROMISING PROTECTION: Dove Men+Care Extra Fresh Antiperspirant deodorant’s revolutionary formula gives you powerful 72-hour sweat and odor protection while moisturizing your skin.
- NON-IRRITANT FORMULA: Designed with ¼ moisturizer, our antiperspirant deodorant helps retain skin moisture and protect against irritation for more comfortable underarms.
- LONG LASTING FRAGRANCE: Dove Men+Care Extra Fresh Antiperspirant Deodorant features a reinvigorating, long-lasting citrus scent to keep you feeling fresh all day.
- 1/4 MOISTURIZING CREAM: Dove Men+Care antiperspirant uses our exclusive care for comfortable underarms all day.
- HOW TO USE: Apply this antiperspirant deodorant stick evenly on your underarms for comfortable underarms and all-day confidence.
$15.48
SALE
−$0.30
Degree Advanced Protection Antiperspirant Deodorant White Flowers & Lychee for 72-Hour Sweat & Odor Control for Women, with Body Heat Activated Technology, 2.6 oz
- NONSTOP FRESHNESS: Degree White Flowers & Lychee Advanced Protection Antiperspirant Deodorant keeps you feeling fresh and clean with 72-hour sweat and odor protection.
- YOU MOVE, IT WORKS: Our breakthrough Body Heat Activated technology works in sync with your body all day. This antiperspirant deodorant releases a burst of fragrance every time you move.
- REFRESHING SCENT: This antiperspirant for women features the fruity, floral scent of lychee and white flowers.
- HOWEVER, YOU MOVE: Keep moving with this antiperspirant deodorant. Just twist, swipe, and move with confidence.
- RECYCLE WITH DEGREE: As well as increasing our use of reusable materials, we’re making it easier for you to recycle our antiperspirant and dry spray packaging.
$4.99
Old Spice Aluminum Free Antiperspirant Deodorant For Men, High Endurance, 24/7 Sweat Defense & Odor Protection, 24/7 Freshness & Lasting Scent, Pure Sport Scent, 3.0 oz (Pack of 2)
- ADVANCED SWEAT & ODOR PROTECTION
- Helps ELIMINATE Odors Instead of Just Masking
- FEEL FRESHER LONGER
- A good offense without smelling offensive.
- Old Spice High Endurance for men has the sweat and odor protection you need and the scent you deserve
$7.26
Certain Dri Everyday Strength Clinical Solid Antiperspirant, Hyperhidrosis Treatment for Men & Women, Long-Lasting 72hr Protection, Effective Sweat Control, Travel Friendly, Fresh Scent, 2.6oz
- #1 Doctor Recommended: Trusted by doctors as the leading clinical antiperspirant brand for treating excessive sweating and hyperhidrosis.
- Clinical Strength Formula: Features a powerful antiperspirant ingredient that provides clinical strength sweat protection without requiring a prescription.
- All-Day Solid Protection: Effective solid deodorant for all-day sweat protection, formulated with 20% Aluminum Zirconium Complex, the same active ingredient used in the majority of clinical antiperspirants.
- Application Instructions: Apply at night to completely dry underarms for optimal effectiveness. Can be reapplied in the morning for an additional layer of freshness and protection throughout the day.
- Important Usage Notes: This antiperspirant contains a potent active ingredient designed to halt excessive sweating. To minimize the risk of irritation, apply sparingly at night to dry skin. Avoid using immediately after showering, shaving, or on irritated skin.
$10.75
Vanicream Anti-Perspirant Deodorant for Sensitive Skin - 2.25 oz - Clinical-Strength Deodorant with 24-Hour Protection - Unscented
- Clinical-strength deodorant: 24-hour, extra-protective deodorant and anti-perspirant for men and women
- Mild formula: Ideal for sensitive skin; our formula is ethanol-free, gluten-free, and does not contain botanical extracts
- Free of common chemical irritants: Our products are free of dyes, fragrance, masking fragrance, lanolin, parabens and formaldehyde releasers
- Dermatologist tested: Vanicream products are formulated with ingredients dermatologists consider desirable and not irritating or sensitizing to the skin
- Directions: For best results, evenly spread a small amount to clean underarms daily
$11.25
SweatBlock Clinical Antiperspirant for Men & Women | Hyperhidrosis Treatment Wipes for Excessive Sweating | Block Sweat for up to 7 days | 10 Wipes
- TIRED OF EMBARRASSING AND UNWANTED SWEAT? - Wear the clothes you love and stay confident with sweat blocking underarm antiperspirant wipes. These wipes contain verified pure aluminum chloride, the most effective aluminum for stopping excessive sweat. Also effective as a clinical strength deodorant. Strong anti sweat & odor prevention for men, women, and teens.
- PRESCRIPTION STRENGTH FOR HYPERHIDROSIS TREATMENT & EXCESSIVE SWEAT - Our time-tested clinical strength antiperspirant wipes are strong enough for hyperhidrosis, nervous sweating, hormonal sweating, and perspiration due to prescription drug side-effects. Deodorant wipes proven to stop unwanted sweat.
- TAKE BACK YOUR CONFIDENCE - Enjoy life without worrying about sweat. Hug, high-five, and raise your arms without worry. Get quick, overnight sweat stopping results with SweatBlock Antiperspirant. Our wipes also work great as a clinical strength deodorant to stop underarm sweat & underarm odor.
- DOCTOR CREATED. DOCTOR RECOMMENDED - Our Founder, Dr. Steffensen experienced a first-hand battle with excessive sweating. After store-bought deodorants & antiperspirants failed him, he created the trade-secret SweatBlock formula to stop unwanted sweat. Today, our wipes are clinically tested with verified pure ingredients & trusted worldwide. SweatBlock is safe, strong, and proven. Featured on The Rachael Ray Show & The Today Show.
- No animal testing. Free from Parabens, Phthalates, Formaldehydes, & Sulfates. Formulated, filled, & sealed in the USA!
$19.99
Medline MedSpa Roll-On Antiperspirant Deodorant, 1.5 oz, Long-Lasting Freshness, 1 Count
- Long Lasting Protection: Medline MedSpa Roll-On Antiperspirant Deodorant offers enduring protection against sweat and body odor, ensuring you remain fresh and confident throughout the day, irrespective of your daily activities
- Alcohol-free formula: Medline MedSpa Roll-On Antiperspirant Deodorant is alcohol-free for lower chance of skin irritation and drying
- Non-staining: This product is designed not to stain clothing, allowing users to apply it confidently without worrying about unsightly marks on their garments
- Fresh scent: The antiperspirant deodorant features a lightly scented formula, providing a pleasant and fresh fragrance for the user
- Pack Size: The Medline MedSpa Roll-On Antiperspirant Deodorant is available in a compact 1.5 oz size, ideal for on-the-go use, fitting easily into a purse, gym bag, or carry-on luggage
$5.98
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API