Antihistamine for runny nose are essential for alleviating the discomfort caused by allergies and colds. In 2025, the market offers a variety of effective options that can help reduce nasal congestion and sneezing. Some of the top choices include both first-generation antihistamines, known for their sedative effects, and newer, non-drowsy formulations that provide relief without causing fatigue. Whether you prefer a liquid, tablet, or nasal spray, there are numerous products available to suit your needs and preferences.
SALE
−$6.35
Benadryl Ultratabs Antihistamine Allergy Relief Medicine, Diphenhydramine HCl Tablets For Relief of Cold & Allergy Symptoms Such as Sneezing, Runny Nose, & Itchy Eyes & Throat, 100 ct
- ALLERGY MEDICATION: Benadryl Allergy Tablets for allergy relief helps to alleviate symptoms associated with allergies such as sneezing, runny nose, itchy throat or nose, and itchy/watery eyes; Powerful allergy and cold relief in just 1 pill
- ANTIHISTAMINE: Allergy medication that temporarily provides allergy & cold relief for hay fever and other upper respiratory symptoms such as sneezing and runny nose; Relief from common allergens such as tree pollen, dust, mold and pet dander.
- COLD SYMPTOM RELIEF: Allergy antihistamine with diphenhydramine is formulated to help relieve multi-symptom allergy relief and cold symptom relief; Effective and powerful formula that works when you need it most
- DIPHENHYDRAMINE FORMULA: Benadryl allergy medicine contains 25 mg of diphenhydramine HCl, an antihistamine that works to help provide allergy and upper respiratory relief.
- INCLUDES: Pack of 1, 100 ct allergy and cold relief medicine; Suitable for adults and children ages 6+; Safe and effective doctor-recommended allergy medicine
$13.39
SALE
−$2.03
Benadryl Liqui-Gels Allergy Medicine, Dye-Free Liquid Gel Capsules with 25 mg of Diphenhydramine HCl Antihistamine for Relief of Allergy & Cold Symptoms Like Runny Nose & Sneezing, 24 ct
- ALLERGY RELIEF MEDICATION: 24-count package of Benadryl Dye-Free Allergy Relief Liquid Gels to help alleviate symptoms associated with allergies such as sneezing, runny nose, itchy throat or nose, and itchy, watery eyes
- POWERFUL ANTIHISTAMINE: This allergy medicine temporarily provides relief of hay fever and other upper respiratory symptoms such as sneezing and runny nose. It also provides relief from common allergens such as tree pollen, dust, mold and pet dander
- COLD SYMPTOM RELIEF: The antihistamine tablets with diphenhydramine hydrochloride feature an effective and powerful formula that works when you need it most. The tablets for multi-symptom relief help tackle both cold and allergy symptoms
- DYE-FREE DIPHENHYDRAMINE HCl FORMULA: Made with a dye free formula, Benadryl allergy medicine contains 25 mg diphenhydramine hydrochloride, an antihistamine that works to help provide allergy and upper respiratory relief
- POWERFUL ALLERGY & COLD SYMPTOM RELIEF IN JUST 1 PILL: Adults & children 12+, take one to two allergy liquid gels every four to six hours. Children ages 6-12, take one allergy medicine tablet every four to six hours. Do not give more than 6 doses in 24 hours
$6.99
SALE
−$4.00
HealthA2Z® Allergy Relief | Loratadine 10mg | Antihistamine | Non-Drowsy | Relief from Itchy Throat, Sneezing, Runny Noses | 24-Hours Allergy Medicine (300 Tablets)
- HealthA2Z Allergy Relief Loratadine 10mg Compare to Claritin Tablets Active Ingredient
- Multi-symptom relief: HealthA2Z Allergy Relief provides allergy relief from sneezing, runny nose, itchy, watery eyes, and itchy nose or throat caused by allergens like pollen, dust mites, pet dander, and mold.
- Non-drowsy: HealthA2Z Allergy Relief, Loratadine 10mg is a non-drowsy antihistamine. Avoid daytime sleepiness.
- 24-hour allergy relief: HealthA2Z Allergy Relief, Loratadine 10mg allows you to get 24-hour allergy relief.
- Adults: Take 1 tablet daily, no more than 1 tablet in 24 hours.
$9.95
Amazon Basic Care 24 Hour Allergy Relief, Levocetirizine Dihydrochloride Tablets, 5 mg, Antihistamine, Relieves Sneezing, Runny Nose, Itchy Nose or Throat and Itchy, Watery Eyes, 80 Count
- ACTIVE INGREDIENT: This Amazon Basic Care product contains levocetirizine dihydrochloride, an antihistamine which compares to the active ingredient in XYZAL Allergy 24HR
- ALL DAY ALLERGY RELIEF: This allergy medication provides 24 hour symptom relief from indoor and outdoor allergens
- WORKS FAST: Clinically proven relief in 60 minutes
- INDOOR AND OUTDOOR ALLERGENS: Provides all day allergy relief by temporarily relieving symptoms due to hay fever or other upper respiratory allergies: sneezing, runny nose, itchy nose or throat and itchy, watery eyes
- GLUTEN FREE: Amazon Basic Care Levocetirizine Dihydrochloride Tablets, 5 mg, are gluten free
$22.95
SALE
−$3.59
Benadryl Ultratabs Antihistamine Allergy Relief Medicine, 25 mg Diphenhydramine HCl Tablets for Relief of Cold & Allergy Symptoms Such as Sneezing, Runny Nose, & Itchy Eyes & Throat, 48 ct
- 48-count pack of Benadryl Ultratabs Antihistamine Allergy Relief Tablets with 25 mg diphenhydramine HCl for powerful allergy & cold relief in 1 pill* *temporarily relieves runny nose & sneezing due to upper respiratory allergies or the common cold
- The small, oval shaped coated tablets with the antihistamine diphenhydramine HCl provides relief for hay fever or other upper respiratory allergy symptoms & cold symptoms like sneezing & runny nose
- Effective & powerful multi-symptom allergy relief for unexpected allergies from an allergist recommended brand. Works when you need it most.
- A trusted allergy brand, Benadryl Ultratabs provide powerful relief for unexpected allergies & relieves symptoms like sneezing, runny nose & itchy, watery eyes & cold symptoms like sneezing & runny nose
- Allergy medicine from a doctor recommended brand for safe & effective*** allergy relief in a small, easy-to-swallow tablet form to be used by adults & children ages six & up for relief of both indoor & outdoor allergies ***when used as directed
$8.88
GenCare - Cetirizine HCL 10 mg (200 Caplets) - 24 Hour Allergy Relief Pills - Non Drowsy Generic OTC Allergy Medication - Antihistamine Medicine for Sneezing, Runny Nose & Itchy Eyes - Generic Zyrtec
- FULL 24 HOUR RELIEF - Enjoy non drowsy allergy relief that lasts for a full day. Cetirizine HCL over the counter medication helps alleviate symptoms of indoor and outdoor allergies like hay fever, pollen, dust, pet dander and seasonal allergies.
- BULK SAVINGS - Each bottle contains 200 individual ready to swallow caplets so that you and your family can always have allergy support on hand. Our pills have a convenient indentation slot if you want to break the pill up into two 5 mg tabs for less severe symptoms or quick relief. Compare to generic Zyrtec active ingredients.
- FAST ITCH RELIEF - Cetirizine HCL is a powerful antihistamine that helps relieve and prevent itchy watery eyes, runny nose, congestion and an irritated itchy throat. If you suffer from hives, cetirizine HCL 10mg may help reduce the itching and appearance of hives on your skin and face.
- NON DROWSY FORMULA - Unlike most allergy medications, Cetirizine HCL tablets are non drowsy and can be taken at any time of day. Directions: Adults and children 6 years and older; one 10 mg tablet once daily; do not take more than 10 mg tablet in 24 hours.
- 100% SATISFACTION GUARANTEE - You don't have to suffer through indoor or outdoor allergies anymore! Get full non drowsy 24 hour allergy relief now and enjoy our 100% Customer Satisfaction Guarantee. Join thousands of satisfied customers...Click Add-to-Cart, Buy Now or Subscribe & Save Today!
$9.99
SALE
−$8.94
Allegra Adult 24-Hour Allergy Relief Tablets, Non-Drowsy Indoor and Outdoor Allergy Medicine, 180 mg Fexofenadine HCI Antihistamine Pill, 100-Count
- INCLUDES: One (1) 100-count pack of Allegra Adult 24-Hour Allergy Relief Tablets, Non-Drowsy Allergy Medicine
- 24-HOUR RELIEF: Take Allegra antihistamine pill day or night for round-the-clock relief from your worst allergy symptoms
- NON-DROWSY: Formulated with active ingredient fexofenadine, a non-drowsy OTC medication with 0% brain interference
- FAST-ACTING: Allegra 24-hour allergy medicine starts working in one hour for fast* relief from sneezing, runny nose, itchy and watery eyes, and itchy nose or throat
- INDOOR & OUTDOOR ALLERGIES: Use Allegra tablets for outdoor and indoor allergens like pollen, ragweed, grass, trees, dust, mold, and pet dander
$35.45
HealthA2Z® Allergy Relief | Levocetirizine Dihydrochloride 5mg | 24 Hours | Antihistamine | Relief from Sneezing, Runny Nose, Itchy Nose and Eyes (60 Counts)
- Lecovetirizine Dihydrochloride 5mg.
- 24 Hours Allergy Relief.
- Uses temporarily relieves these symptoms due to hay fever or other upper respiratory allergies: Sneezing, Runny Nose, Itchy Nose or Throat and Itchy Watery Eyes.
$6.99
SALE
−$1.73
Benadryl Allergy Plus Congestion Ultratabs with Diphenhydramine HCl Antihistamine & Phenylephrine HCl Nasal Decongestant, Allergy & Sinus Congestion Relief Tablets, 24 ct
- 24-count pack of Benadryl Allergy Plus Congestion Ultratabs nasal decongestant & antihistamine allergy relief tablets containing both diphenhydramine HCl and phenylephrine HCl for allergy relief you can trust + fast congestion relief
- Formulated to alleviate allergy symptoms caused by hay fever & other upper respiratory allergies, Benadryl Allergy + Congestion dries runny, stuffy noses so you can breathe better & temporarily relieves common cold symptoms like sneezing & congestion
- This allergy medicine contains 25 mg of the antihistamine diphenhydramine HCl & 10 mg of the nasal decongestant phenylephrine HCl in every allergy relief tablet that work to help alleviate sinus congestion & allergy symptoms
- Get temporary relief of cold symptoms like runny nose, sneezing, nasal congestion & sinus pressure with a formula that offers a nasal decongestant & antihistamine in one tablet.
- From a doctor-recommended brand, this allergy medicine is suitable for ages 12 and up and provides safe & effective relief (when used as directed) from symptoms due to indoor & outdoor allergies as well as congestion due to the common cold
$7.29
Rite Aid Sinus & Allergy Relief PE Tablets, Maximum Strength- 24 Count | Antihistamine and Nasal Decongestant | 4 Hour Medication | Nasal Allergy and Congestion Relief Tablets
- 4 HOUR RELIEF: Rite Aid’s Sinus & Allergy Relief PE tablets offer temporary relief for up to 4 hours from sinus pressure & congestion, sneezing, itchy, watery eyes, and runny nose. This allergy medicine calms hay fever or other respiratory allergies.
- MULTI-SYMPTOM RELIEF: Get the same active ingredients as the national brand, Rite Aid Maximum Strength Sinus & Allergy Relief PE contains Chlorpheniramine Maleate 4mg & Phenylephrine HCI 10mg compared to top brands
- ANTIHISTAMINE + NASAL DECONGESTANT: With Rite Aid allergy and congestion relief tablets, temporarily calm symptoms from allergies, the common cold, and hay fever for adults and children 12 years of age and older.
- CONTROL INDOOR & OUTDOOR ALLERGIES: Allergies don’t stand a chance against Rite Aid’s allergy and cold medicine for adults. Whether it’s pet dander or dust indoors or blooming grass and trees outside, Rite Aid will keep your allergies under control.
- TRUSTED BRAND SINCE 1962: We hope you continue to choose us first for your everyday health and wellness needs. Our mission is to improve the health and wellness of our communities and provide our customers with the best products, services, and advice.
$12.99
Last update on 2025-05-03 / Affiliate links / Images from Amazon Product Advertising API