Anti itch medicine is essential for alleviating discomfort caused by various skin irritations, allergies, and insect bites. In 2025, the market offers a range of effective solutions, from topical creams and ointments to oral antihistamines, ensuring relief for everyone. Popular options include hydrocortisone cream, calamine lotion, and natural remedies like aloe vera. These products not only soothe itching but also promote healing, making them must-haves in any first aid kit. Whether you're dealing with seasonal allergies or a pesky bug bite, the right anti itch medicine can make all the difference in your comfort and well-being.
SALE
−$2.19
Benadryl Anti Itch Gel, Relief of Outdoor Itches Associated with Poison Ivy, Topical Analgesic, Cooling Relief, Diphenhydramine, 3.5 oz
- ANTI ITCH GEL: Benadryl anti itch gel temporarily provides pain and itch relief associated with insect bites, minor burns, sunburn, minor skin irritation, minor cuts and scrapes, and rashes due to poison ivy and poison sumac.
- TOPICAL ANALGESIC: Topical cooling gel contains 2% of the topical analgesic pain reliver diphenhydramine hydrochloride that helps to relieve itches and minor pains on the skin; Provides relief from most outside itches.
- SOOTHING & COOLING GEL: Carry this topical anti itch analgesic gel to relieve uncomfortable skin irritation at home or on the go; Works when you need it most and provides cooling relief from minor pain to intolerable itchy skin.
- POISON IVY REIEF: Topical Analgesic to provide itch relief for most outdoor itches associated with poison ivy, insect bites; Dries the oozing and weeping of poison ivy, poison oak and poison sumac.
- INCLUDES: Pack of 1, 3.5 fl. oz. anti itch gel; Suitable for adults and children ages 2+; Provides itch relief for kids and adults alike and great to keep on hand during outdoor activities such as camping, hiking, or walking with the family.
$6.27
SALE
−$0.69
Cortizone 10 Maximum Strength Anti-Itch Cream with Soothing Aloe, 1% Hydrocortisone Creme, 2 oz.
- Contains: One (1) 2-oz. tube of Cortizone 10 Maximum Strength Soothing Aloe Anti-Itch Cream
- Fast relief of itch and inflammation associated with eczema, psoriasis, and poison oak, ivy, and sumac
- Features 1 percent hydrocortisone, the maximum-strength itch relief without a prescription
- Relieves itch in under 10 minutes and lasts for hours
- Cortizone 10 anti-itch cream with aloe is fragrance free and dye free
$7.30
Allegra Hives Antihistamine 24-Hour Tablets, Non-Drowsy Hive Reduction and Hive Itch Relief, 180 mg Fexofenadine HCI, 30-Count
- INCLUDES: One (1) 30-count pack of Allegra Hives Antihistamine 24-Hour Tablets, Non-Drowsy Itch Relief
- 24-HOUR RELIEF: One antihistamine pill is all you need for 24-hour relief
- NON-DROWSY: Formulated with active ingredient fexofenadine HCI, a non-drowsy OTC medication
- ITCH RELIEF: Allegra Hives itch relief medicine works from the inside to reduce hives and relieve itching due to hives
- REDUCES SYMPTOMS: Use Allegra tablets for hives related symptoms
$19.96
Cortizone 10 Maximum Strength Fast Itch Relief with Massaging Rollerball, 1% Hydrocortisone Anti-Itch Liquid, 1.5 oz.
- Contains: One (1) 1.5 oz. tube of Cortizone 10 Maximum Strength Fast Itch Relief With Massaging Rollerball
- Fast relief of itch and inflammation associated with rashes, insect bites, and ivy and sumac
- Formulated with seven moisturizers and enriched with aloe to comfort skin
- Features 1% hydrocortisone, the maximum strength itch relief without a prescription
- Massaging rollerball applicator allows for no mess, no touch relief
$9.99
Amazon Basic Care Maximum Strength Anti-Itch Cream, Hydrocortisone 1 Percent Intensive Healing Formula, Itch Relief For Bug Bites, Eczema, Psoriasis, Poison Ivy, Oak and Sumac, 1 ounce (Pack of 1)
- ACTIVE INGREDIENT: The active ingredient in this anti-itch cream is hydrocortisone 1 percent; compare to the active ingredient in Cortizone 10 Intensive Healing Formula
- MAXIMUM STRENGTH RELIEF: Hydrocortisone is the number one doctor recommended anti-Itch active Ingredient (of U.S. physicians surveyed by an independent market research firm)
- POWERFUL MEDICINE, FAST RELIEF: Great for relieving itching associated with skin irritation, rashes, inflammation, redness, insect bites, eczema, psoriasis and poison ivy, oak and sumac
- LASTS UP TO 10 HOURS when used as directed; ultra creamy, maximum strength hydrocortisone formula helps heal problem skin; safe for sensitive skin; for adults and children age 2 years of age and older
- INTENSIVE HEALING FORMULA calms, nourishes and hydrates; clinically proven to moisturize for up to 24 hours; features antioxidants, chamomile and Vitamins A, C and E
$5.87
SALE
−$6.35
Benadryl Ultratabs Antihistamine Allergy Relief Medicine, Diphenhydramine HCl Tablets For Relief of Cold & Allergy Symptoms Such as Sneezing, Runny Nose, & Itchy Eyes & Throat, 100 ct
- ALLERGY MEDICATION: Benadryl Allergy Tablets for allergy relief helps to alleviate symptoms associated with allergies such as sneezing, runny nose, itchy throat or nose, and itchy/watery eyes; Powerful allergy and cold relief in just 1 pill
- ANTIHISTAMINE: Allergy medication that temporarily provides allergy & cold relief for hay fever and other upper respiratory symptoms such as sneezing and runny nose; Relief from common allergens such as tree pollen, dust, mold and pet dander.
- COLD SYMPTOM RELIEF: Allergy antihistamine with diphenhydramine is formulated to help relieve multi-symptom allergy relief and cold symptom relief; Effective and powerful formula that works when you need it most
- DIPHENHYDRAMINE FORMULA: Benadryl allergy medicine contains 25 mg of diphenhydramine HCl, an antihistamine that works to help provide allergy and upper respiratory relief.
- INCLUDES: Pack of 1, 100 ct allergy and cold relief medicine; Suitable for adults and children ages 6+; Safe and effective doctor-recommended allergy medicine
$13.39
HealthA2Z® Allergy Relief | Cetirizine 10mg | All Day Allergy Relief | Indoor & Outdoor | Relief from Itchy Throat, Sneezing, Runny Noses (300 Count (Pack of 1))
- HealthA2Z Allergy Relief | Cetirizine 10mg | All Day Allergy Relief | Indoor & Outdoor | Relief from Itchy Throat, Sneezing, Runny Noses |
$9.95
SALE
−$1.78
Benadryl Extra Strength Anti-Itch Topical Cream with 2% Diphenhydramine HCI for Itch Relief of Outdoor Itches Associated with Poison Ivy, Insect Bites & More, 1 fl oz
- 1-ounce tube of Benadryl Extra-Strength Anti-Itch Cream temporarily relieves pain and itching associated with insect bites, minor burns, sunburn, minor skin irritations, minor cuts, scrapes and rashes due to poison ivy, poison oak and poison sumac
- Topical analgesic cream works when you need it most and provides cooling, anti-itch relief from most minor pains and outdoor itches associated with insect bites, sunburn, scrapes, minor skin irritations, burns and minor cuts
- The cooling cream provides the relief of pain and itching associated with sunburn, relieves outdoor itches associated with poison ivy, insect bites and more and dries the oozing and weeping of poison ivy, poison oak and poison sumac
- Cooling cream that provides relief from most outdoor itches contains 2% of the topical analgesic pain reliever diphenhydramine hydrochloride that relieves itches and minor pains on the skin and works when you need it most
- Intended for use by those ages 2 and up, soothing cream offers itch relief for kids and adults alike and is great to keep on hand for relief during outdoor activities such as camping, hiking or taking a walk with the family
$4.88
CeraVe Anti Itch Moisturizing Lotion with Pramoxine Hydrochloride, Relieves Itch with Minor Skin Irritations, Sunburn Relief, Bug Bites, 8 Ounce
- [ CERAVE ANTI ITCH LOTION ] Temporarily relieves itching associated with insect bites, sunburn, poison ivy while moisturizing dry skin. Lightweight texture that is absorbed quickly for softened skin with non-greasy feel.
- [ CLINICALLY TESTED ] Provides relief within two minutes and lasts up to 8 hours. 100 percent of people experienced relief for even their most severe itch; clinical study done on 34 subjects. Individual results may vary.
- [ SOOTHING INGREDIENTS ] Formulated with 1% Pramoxine Hydrochloride for fast-acting, long-lasting temporary itch-relief, Niacinamide to help calm skin, and Hyaluronic Acid to help retain skin’s natural moisture.
- [ 3 ESSENTIAL CERAMIDES ] Ceramides are found naturally in the skin and make up 50% of the lipids in the skin barrier. All CeraVe products are formulated with three essential ceramides (1, 3, 6-II) to help restore and maintain the skin’s natural barrier
- [ DEVELOPED WITH DERMATOLOGISTS ] Suitable for use on face; body; and hands to temporarily relieve itching. Holds National Eczema Association (NEA) Seal of Acceptance. Fragrance free; steroid-free; and non-comedogenic. FSA Eligible & HSA Eligible
$17.99
Aquaphor Itch Relief Ointment, Maximum Strength 1% Hydrocortisone, Relieves Itch from Skin Irritation, Insect Bites, Psoriasis, Skin Rashes, Eczema, & Poison Ivy, 2 oz
- Long Lasting Itch Relief: Aquaphor Itch Relief ointment soothes and relieves itch and irritation for up to 12 hours
- Outdoor Irritation Relief: Clinically proven to help provide instant itch relief for outdoor irritations like insect bites, poison ivy, poison oak, and sumac
- Indoor Itch Relief: This skin ointment can also help to soothe and relieve itchiness from indoor causes like dry skin, skin rash, and psoriasis
- Helps Heal the Itch: Formula features 1% hydrocortisone anti itch ointment, and is fragrance free, paraben free, and hypoallergenic
- Includes one (1) 2 ounce tube of Aquaphor Itch Relief Ointment
$13.49
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API