Acne serum is an essential part of any skincare routine for those struggling with breakouts and blemishes. In 2025, the market is flooded with innovative formulations designed to target acne at its source, providing effective solutions for all skin types. From serums infused with salicylic acid to those enriched with natural ingredients like tea tree oil and niacinamide, the best options not only help clear existing acne but also prevent future outbreaks. With a focus on hydration and skin barrier support, these serums are a must-try for anyone looking to achieve a clearer complexion.
The Ordinary Salicylic Acid 2% Solution, Acne-Fighting Serum for Blemish-Prone Skin, 1 Fl Oz
- TARGETS ACNE & CONGESTION: Salicylic Acid 2% Solution treats acne by exfoliating the skin surface and penetrating pores to control blemishes.
- HELPS SKIN HEAL: Formulated to reduce the severity of acne and allow the skin to heal for a smoother, clearer complexion.
- SUITABLE FOR TEENAGERS: Effective for mild to moderate acne in teenagers, offering a gentle yet powerful solution for acne-prone skin.
- OIL-SOLUBLE FORMULA: Lipophilic formula that penetrates oily areas to treat clogged pores and reduce acne-related skin issues.
- APPLICATION INSTRUCTIONS: Clean skin thoroughly and apply a thin layer 1-3 times daily. Patch test before use. Reduce application if dryness or irritation occurs.
$6.70
SALE
−$3.31
CeraVe Resurfacing Retinol Serum For Post Acne Marks, Formulated With Licorice Root Extract & Niacinamide, Brightening Serum & Pore Minimizer For Face, Post Acne Skin Barrier Repair, Non-Comedogenic
- [ POST ACNE RETINOL SERUM FOR FACE ] With encapsulated retinol, this facial serum helps skin look smoother and more even-toned. Pore minimizer helps refine skin’s texture & helps visibly reduce the appearance of post-acne marks and blemishes.
- [ SKIN BARRIER REPAIR ] This retinol face serum smooths skin texture, reduces acne marks, and brightens skin. Reducing the look of post inflammatory hyperpigmentation while repairing the skin's barrier.
- [ BRIGHTENING SERUM ] Formulated with licorice root extract helps to brighten the appearance of skin and niacinamide helps to calm skin. Fragrance free, paraben-free, and non-comedogenic. Pore reducer for face.
- [ 3 ESSENTIAL CERAMIDES ] Ceramides are found naturally in the skin and make up 50% of the lipids in the skin barrier. All CeraVe products, formulated with three essential ceramides (1, 3, 6-II)to help maintain the skin’s natural barrier.
- [ DEVELOPED WITH DERMATOLOGISTS ] CeraVe Skincare is developed with dermatologists and has products suitable for dry skin, sensitive skin, oily skin, acne-prone, and more.
$18.68
Good Molecules Niacinamide Serum - 10% Niacinamide Balancing B3 Facial Serum for Acne, Tone, Texture - Brightening and Hydrating Skincare for Face
- BRIGHT AND HEALTHY COMPLEXION: Refine tone and improve texture while nourishing your skin! Embrace newfound confidence with the Good Molecules Niacinamide Serum!
- SOOTHING AND NON-DRYING: Beneficial for acne prone skin and clogged pores. This serum is non-drying and designed to help to reduce signs of moisture loss caused by a weak skin barrier function.
- PROMOTE SMOOTH AND EVEN SKIN: This balancing formula is rich in Niacinamide (10%), also known as B3, and can be very helpful for those suffering from breakouts, uneven skin tone, enlarged pores, and dull texture.
- PERFECT ADDITION TO YOUR BEAUTY REGIMEN: Apply a few drops to your skin in the morning and at night before oils, moisturizers, and creams. Our serum is powerful enough to bring results and gentle enough for daily use.
- GENTLE ENOUGH FOR ALL SKIN TYPES: This serum is suitable for all skin types, but can be particularly beneficial for those with combination/oily skin. Our serum has a pH of 7.1, is fragrance-free, and was never tested on animals. Since everyone's skin is unique, we recommend performing a patch test before using this product to ensure compatibility and avoid any potential reactions.
$6.00
The Ordinary Niacinamide 10% + Zinc 1%, Smoothing Serum for Blemish-Prone Skin, 1 Fl Oz
- BOOSTS BRIGHTNESS & SMOOTHNESS: Niacinamide 10% + Zinc 1% visibly improves skin radiance and smooths texture in one week.
- HYDRATING FORMULA: Lightweight water-based serum that reinforces the skin barrier and provides hydration in as little as 7 days.
- CONTAINS NIACINAMIDE & ZINC PCA: High 10% concentration of Niacinamide (Vitamin B3) and 1% Zinc PCA to help control oil in 3 days.
- REDUCES PORE VISIBILITY: Clinical testing shows appearance of pores is minimized in 4 weeks, improving signs of congesting.
- APPLICATION INSTRUCTIONS: Apply a few drops to the face in the morning and evening. Patch test before use and avoid broken skin.
$6.00
La Roche-Posay Effaclar Salicylic Acid Treatment to Minimize Pores, Clear Acne Blemishes and Post Acne Marks
- This anti-aging pore minimizer face serum helps reduce the look of pores, smooth skin texture and boost skin radiance.
- Formulated with glycolic acid, hyaluronic acid and micro-exfoliating lipo-hydroxy acid, this face serum for oily skin targets fine lines, reduces enlarged pores and visibly tightens skin.
- Face serum for oily skin visibly reduces the look of pores, Targets fine lines, reduces enlarged pores & visibly tightens skin
- Lipo-Hydroxy Acid: Also known as LHA, it's a derivative of salicylic acid, and has exfoliating and skin surface renewing properties.
- Glycolic Acid: An Alpha-Hydroxy Acid (AHA) often considered the gold standard in dermatology for skin exfoliation. Within our formulas, it is recognized for its ability to increase skin surface cell turnover and help visibly improve skin tone and texture.
$42.99
Cocokind Postbiotic Acne Serum, Salicylic Acid Serum and BHA Liquid Exfoliant - Exfoliating, Brightening and Hydrating Serum
- Cocokind Postbiotic Acne Serum is a face serum to help with acne, blackheads, and clogged pores.
- Postbiotic Acne Serum uses 1.5% Salicylic Acid and Postbiotics to exfoliate the skin, decongest pores, and reduce excess oil and the look of inflammation and redness.
- Postbiotic Acne Serum is also a hydrating serum using Beta Glucan (derived from oats) to lock in hydration and support the skin barrier.
- If you are new to BHA, use Postbiotic Acne Serum 3-4 times a week before building up to daily usage. Use with Texture Smoothing Cream and Silk or Daily SPF to finish your skincare routine.
- COCOKIND: Skin care products that are earth-friendly without compromising on formulation. Our products are meant to gently deliver the function they promise as well as hydration and skin barrier support, which we believe leads to glowy, happy skin
$19.97
SALE
−$3.02
CeraVe Acne Control Gel, 2% Salicylic Acid Treatment With Glycolic Acid + Lactic Acids + Niacniamide, Acne Gel Helps Clear Blemishes Without Over Drying, Alcohol Free & Oil Free, 1.35 Fl Oz
- [ACNE TREATMENT WITH BHA/AHA EXFOLIANT] Formulated with 2% salicylic acid and a blend of glycolic acid and lactic acid, this acne spot treatment for face helps clear acne and prevent new breakouts, acting as an effective face exfoliator.
- [PORE MINIMIZER FOR FACE] This acne skincare product minimizes the appearance of pores and reduces blackheads with its potent mix of niacinamide and hyaluronic acid, enhancing skin moisture and soothing properties.
- [ALCOHOL FREE & HYDRATING GEL] Free from fragrance, parabens, and oil, this non-comedogenic acne spot treatment is designed without harsh alcohols, preventing excessive dryness while treating stubborn acne effectively.
- [ 3 ESSENTIAL CERAMIDES ] Ceramides are found naturally in the skin and make up 50% of the lipids in the skin barrier. All CeraVe products, formulated with three essential ceramides (1, 3, 6-II)to help maintain the skin’s natural barrier.
- [ DEVELOPED WITH DERMATOLOGISTS ] CeraVe Skincare is developed with dermatologists and has products suitable for dry skin; sensitive skin; oily skin; acne-prone; and more. FSA Eligible & HSA Eligible Acne Skin Care
$17.97
BYOMA Clarifying Serum - Barrier Repair Serum - Clarifying Facial Serum for Acne Prone Skin - Calming Face Serum with Ceramides, Blue Tansy, PHA & Zinc - Balanced & Healthy Skin - 1.01 fl. oz
- BARRIER BOOSTING: This clarifying serum for acne prone skin features our barrier boosting Tri-Ceramide Complex (ceramides, cholesterol, fatty acids) plus a potent combo of blue tansy (rich in antioxidants) to calm, clear and soothe skin
- BALANCE & CLARIFY: PHA and zinc gently exfoliate, targeting imperfections and helping unclog pores without drying out or disrupting the delicate skin barrier. Skin looks balanced, brighter and healthier with regular use
- REDUCES OILINESS & CLEARS PORES: This gentle-yet-effective clarifying facial serum balances spot-prone skin, calms inflammation, reduces oiliness and decongests pores
- ALCOHOL & FRAGRANCE FREE SKINCARE: Dermatologist tested and approved skin care, soap-free, non-comedogenic, alcohol and fragrance-free, vegan and cruelty free. For all skin types
- DRIVEN BY SCIENCE: When we stop stripping our skin and start boosting our barrier, we find the key to balanced, brighter skin. Driven by science, powered by actives - Byoma is the ultimate skin-compatible solution
$15.84
Cetaphil Gentle Clear Triple-Action Acne Treatment Serum with Salicylic Acid, Treats and Prevents Acne, Great for Post-Acne Marks, for All Skin Types, 1oz
- CETAPHIL GENTLE CLEAR TRIPLE-ACTION ACNE SERUM: Improves the appearance of breakouts in just 3 days and fight the appearance of blemishes with continued use
- A GENTLE WAY TO GET BLEMISH FREE SKIN: Formulated with salicylic acid, succinic acid and PHA to exfoliate the skin and even skin tone
- SOOTHES AND PROVIDES 24 HOUR HYDRATION: Contains soothing niacinamide, zinc, and prebiotics to help preserve the skin's moisture barrier
- GEL SERUM WITH A COMFORTING MILKY TEXTURE: Fragrance free, hypoallergenic and non-comedogenic, designed to be gentle on sensitive skin
- DEFENDS AGAINST 5 SIGNS OF SKIN SENSITIVITY: Dryness, irritation, roughness, tightness and a weakened skin barrier
$15.45
SALE
−$6.99
Thayers Double Action Acne Serum with Salicylic Acid, Acne Treatment Face Serum with 2% Salicylic Acid and Niacinamide, Soothing and Non-Stripping Skin Care, 1 Fl Oz
- Acne Treatment Serum: An acne clearing serum that goes hard on acne without drying your skin? We made that! Thayers Double Action Acne Serum is the ultimate powerhouse for clearing acne, fading post acne marks and healing skin
- Clinically Tested To Clear Acne In 1 Week: Our salicylic acid serum features maximum strength 2% salicylic acid to penetrate pores. Clinically tested to clear acne and smooth skin texture in 1 week, help fade post acne marks & improve hydration in 15 minutes
- Clearing and Healing Actives: Our acne treatment for face features powerful clearing actives including 4% Niacinamide + 3% Lactic Acid fused with healing actives including Azelaic Acid + Hyaluronic Acid + Witch Hazel + Lemon Grass + Aloe
- Non-Stripping Formula: This silky, lightning-fast absorbing face serum maintains your skin's moisture barrier and provides a soothing and calming sensation without stripping skin. Fragrance, alcohol and paraben free and non-comedogenic serum for face
- Dermatologist-Tested Skin Care: For generations, Thayers has been the go-to choice in medicine cabinets. Thayers facial skin care products are dermatologist tested for safety and backed by science to level up your skin—for real results
$13.00
Last update on 2025-05-02 / Affiliate links / Images from Amazon Product Advertising API